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See also: TP53 tumor protein p53 in the Gene database

tp53 in Homo sapiensRattus norvegicusBos taurusAll 74 Gene records

Results: 1 to 20 of 204

1.

[Expression and significance of phosphated signal transducer and activator of transcription 3 and p53 protein in laryngeal squamous cell carcinoma].

Dai L, Liu T, Zhou X, Wei Q, Li Y, Cui C, Li M.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Sep;27(18):991-4. Chinese.

PMID:
24459924
[PubMed - indexed for MEDLINE]
2.

Landscape of genomic alterations in cervical carcinomas.

Ojesina AI, Lichtenstein L, Freeman SS, Pedamallu CS, Imaz-Rosshandler I, Pugh TJ, Cherniack AD, Ambrogio L, Cibulskis K, Bertelsen B, Romero-Cordoba S, Treviño V, Vazquez-Santillan K, Guadarrama AS, Wright AA, Rosenberg MW, Duke F, Kaplan B, Wang R, Nickerson E, Walline HM, Lawrence MS, Stewart C, Carter SL, McKenna A, Rodriguez-Sanchez IP, Espinosa-Castilla M, Woie K, Bjorge L, Wik E, Halle MK, Hoivik EA, Krakstad C, Gabiño NB, Gómez-Macías GS, Valdez-Chapa LD, Garza-Rodríguez ML, Maytorena G, Vazquez J, Rodea C, Cravioto A, Cortes ML, Greulich H, Crum CP, Neuberg DS, Hidalgo-Miranda A, Escareno CR, Akslen LA, Carey TE, Vintermyr OK, Gabriel SB, Barrera-Saldaña HA, Melendez-Zajgla J, Getz G, Salvesen HB, Meyerson M.

Nature. 2014 Feb 20;506(7488):371-5. doi: 10.1038/nature12881. Epub 2013 Dec 25.

PMID:
24390348
[PubMed - indexed for MEDLINE]
3.

Primary Combined Neuroendocrine and Squamous Cell Carcinoma of the Maxillary Sinus: Report of a Case with Immunohistochemical and Molecular Characterization.

Franchi A, Rocchetta D, Palomba A, Innocenti DR, Castiglione F, Spinelli G.

Head Neck Pathol. 2013 Dec 11. [Epub ahead of print]

PMID:
24327102
[PubMed - as supplied by publisher]
4.

Establishment and characterization of a novel HPV-negative laryngeal squamous cell carcinoma cell line, FD-LSC-1, with missense and nonsense mutations of TP53 in the DNA-binding domain.

Wu CP, Zhou L, Gong HL, Du HD, Tian J, Sun S, Li JY.

Cancer Lett. 2014 Jan 1;342(1):92-103. doi: 10.1016/j.canlet.2013.08.041. Epub 2013 Aug 31.

PMID:
24001612
[PubMed - indexed for MEDLINE]
5.

Chk1/2 inhibition overcomes the cisplatin resistance of head and neck cancer cells secondary to the loss of functional p53.

Gadhikar MA, Sciuto MR, Alves MV, Pickering CR, Osman AA, Neskey DM, Zhao M, Fitzgerald AL, Myers JN, Frederick MJ.

Mol Cancer Ther. 2013 Sep;12(9):1860-73. doi: 10.1158/1535-7163.MCT-13-0157. Epub 2013 Jul 9.

PMID:
23839309
[PubMed - indexed for MEDLINE]
6.

Papillary squamous cell carcinoma of the head and neck: clinicopathologic and molecular features with special reference to human papillomavirus.

Mehrad M, Carpenter DH, Chernock RD, Wang H, Ma XJ, Luo Y, Luo J, Lewis JS Jr, El-Mofty SK.

Am J Surg Pathol. 2013 Sep;37(9):1349-56. doi: 10.1097/PAS.0b013e318290427d.

PMID:
23797720
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Association between a rare novel TP53 variant (rs78378222) and melanoma, squamous cell carcinoma of head and neck and lung cancer susceptibility in non-Hispanic Whites.

Guan X, Wang LE, Liu Z, Sturgis EM, Wei Q.

J Cell Mol Med. 2013 Jul;17(7):873-8. doi: 10.1111/jcmm.12076. Epub 2013 Jun 7.

PMID:
23742673
[PubMed - indexed for MEDLINE]
8.

Dual PI3K/mTOR inhibitors: does p53 modulate response?

Ekshyyan O, Anandharaj A, Nathan CA.

Clin Cancer Res. 2013 Jul 15;19(14):3719-21. doi: 10.1158/1078-0432.CCR-13-1291. Epub 2013 Jun 5.

PMID:
23741068
[PubMed - indexed for MEDLINE]
9.

Human papillomavirus tumor-infiltrating T-regulatory lymphocytes and P53 codon 72 polymorphisms correlate with clinical staging and prognosis of oropharyngeal cancer.

Rittà M, Landolfo V, Mazibrada J, De Andrea M, Dell'Oste V, Caneparo V, Peretti A, Giordano C, Pecorari G, Garzaro M, Landolfo S.

New Microbiol. 2013 Apr;36(2):133-44. Epub 2013 Mar 31.

PMID:
23686119
[PubMed - indexed for MEDLINE]
Free Article
10.

PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer.

Herzog A, Bian Y, Vander Broek R, Hall B, Coupar J, Cheng H, Sowers AL, Cook JD, Mitchell JB, Chen Z, Kulkarni AB, Van Waes C.

Clin Cancer Res. 2013 Jul 15;19(14):3808-19. doi: 10.1158/1078-0432.CCR-12-2716. Epub 2013 May 2.

PMID:
23640975
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Serine substitution of proline at codon 151 of TP53 confers gain of function activity leading to anoikis resistance and tumor progression of head and neck cancer cells.

Xie TX, Zhou G, Zhao M, Sano D, Jasser SA, Brennan RG, Myers JN.

Laryngoscope. 2013 Jun;123(6):1416-23. doi: 10.1002/lary.23846. Epub 2013 Apr 26.

PMID:
23625637
[PubMed - indexed for MEDLINE]
12.

Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers.

Pickering CR, Zhang J, Yoo SY, Bengtsson L, Moorthy S, Neskey DM, Zhao M, Ortega Alves MV, Chang K, Drummond J, Cortez E, Xie TX, Zhang D, Chung W, Issa JP, Zweidler-McKay PA, Wu X, El-Naggar AK, Weinstein JN, Wang J, Muzny DM, Gibbs RA, Wheeler DA, Myers JN, Frederick MJ.

Cancer Discov. 2013 Jul;3(7):770-81. doi: 10.1158/2159-8290.CD-12-0537. Epub 2013 Apr 25.

PMID:
23619168
[PubMed - indexed for MEDLINE]
13.

DNA-bound platinum is the major determinant of cisplatin sensitivity in head and neck squamous carcinoma cells.

Martens-de Kemp SR, Dalm SU, Wijnolts FM, Brink A, Honeywell RJ, Peters GJ, Braakhuis BJ, Brakenhoff RH.

PLoS One. 2013 Apr 17;8(4):e61555. doi: 10.1371/journal.pone.0061555. Print 2013.

PMID:
23613873
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins.

Keysar SB, Astling DP, Anderson RT, Vogler BW, Bowles DW, Morton JJ, Paylor JJ, Glogowska MJ, Le PN, Eagles-Soukup JR, Kako SL, Takimoto SM, Sehrt DB, Umpierrez A, Pittman MA, Macfadden SM, Helber RM, Peterson S, Hausman DF, Said S, Leem TH, Goddard JA, Arcaroli JJ, Messersmith WA, Robinson WA, Hirsch FR, Varella-Garcia M, Raben D, Wang XJ, Song JI, Tan AC, Jimeno A.

Mol Oncol. 2013 Aug;7(4):776-90. doi: 10.1016/j.molonc.2013.03.004. Epub 2013 Apr 4.

PMID:
23607916
[PubMed - indexed for MEDLINE]
15.

ISL1 expression is not restricted to pancreatic well-differentiated neuroendocrine neoplasms, but is also commonly found in well and poorly differentiated neuroendocrine neoplasms of extrapancreatic origin.

Agaimy A, Erlenbach-Wünsch K, Konukiewitz B, Schmitt AM, Rieker RJ, Vieth M, Kiesewetter F, Hartmann A, Zamboni G, Perren A, Klöppel G.

Mod Pathol. 2013 Jul;26(7):995-1003. doi: 10.1038/modpathol.2013.40. Epub 2013 Mar 15.

PMID:
23503646
[PubMed - indexed for MEDLINE]
16.

SIRT1 expression is associated with good prognosis for head and neck squamous cell carcinoma patients.

Noguchi A, Li X, Kubota A, Kikuchi K, Kameda Y, Zheng H, Miyagi Y, Aoki I, Takano Y.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Mar;115(3):385-92. doi: 10.1016/j.oooo.2012.12.013.

PMID:
23453030
[PubMed - indexed for MEDLINE]
17.

Clinical correlates of promoter hypermethylation of four target genes in head and neck cancer: a cooperative group correlative study.

Roh JL, Wang XV, Manola J, Sidransky D, Forastiere AA, Koch WM.

Clin Cancer Res. 2013 May 1;19(9):2528-40. doi: 10.1158/1078-0432.CCR-12-3047. Epub 2013 Feb 26.

PMID:
23444219
[PubMed - indexed for MEDLINE]
18.

Mutations of the TP53 gene in adenocarcinoma and squamous cell carcinoma of the cervix: a systematic review.

Tornesello ML, Buonaguro L, Buonaguro FM.

Gynecol Oncol. 2013 Mar;128(3):442-8. doi: 10.1016/j.ygyno.2012.11.017. Epub 2012 Nov 17. Review.

PMID:
23168175
[PubMed - indexed for MEDLINE]
19.

MATH, a novel measure of intratumor genetic heterogeneity, is high in poor-outcome classes of head and neck squamous cell carcinoma.

Mroz EA, Rocco JW.

Oral Oncol. 2013 Mar;49(3):211-5. doi: 10.1016/j.oraloncology.2012.09.007. Epub 2012 Oct 15.

PMID:
23079694
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Treatment choice for locally advanced head and neck cancers on the basis of risk factors: biological risk factors.

Braakhuis BJ, Brakenhoff RH, Leemans CR.

Ann Oncol. 2012 Sep;23 Suppl 10:x173-7.

PMID:
22987957
[PubMed - indexed for MEDLINE]

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