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The Dietary Food Components Capric Acid and Caprylic Acid Inhibit Virulence Factors in Candida albicans Through Multitargeting.
Jadhav A, Mortale S, Halbandge S, Jangid P, Patil R, Gade W, Kharat K, Karuppayil SM. Jadhav A, et al. J Med Food. 2017 Nov;20(11):1083-1090. doi: 10.1089/jmf.2017.3971. Epub 2017 Sep 18. J Med Food. 2017. PMID: 28922057
Our study demonstrated that yeast-to-hyphal signal transduction pathways were affected by capric acid and caprylic acid. ...This research suggests that both capric and caprylic acid may be effective interventions for treating C. albicans yeas …
Our study demonstrated that yeast-to-hyphal signal transduction pathways were affected by capric acid and caprylic acid …
Fatty acid modification of antimicrobial peptide CGA-N9 and the combats against Candida albicans infection.
Li R, Wang X, Yin K, Xu Q, Ren S, Wang X, Wang Z, Yi Y. Li R, et al. Biochem Pharmacol. 2023 May;211:115535. doi: 10.1016/j.bcp.2023.115535. Epub 2023 Apr 3. Biochem Pharmacol. 2023. PMID: 37019190
The biological activities of CGA-N9 analogues were determined. The results showed that the n-octanoic acid conjugation of CGA-N9 (CGA-N9-C8) was the optimal CGA-N9 analogue with the highest anti-Candida activity and biosafety; exhibited the strongest biofilm inhibit …
The biological activities of CGA-N9 analogues were determined. The results showed that the n-octanoic acid conjugation of CGA- …
Medium-chain fatty acid esters are effective even in azole-resistant Malassezia pachydermatis.
Koch C, Nordzieke S, Grieger J, Mayser P. Koch C, et al. Mycoses. 2022 Dec;65(12):1188-1193. doi: 10.1111/myc.13512. Epub 2022 Aug 16. Mycoses. 2022. PMID: 35923130
As shown by GC analysis with the reference strains CBS 1879 and CBS 1892 and 3-hydroxypropyl caprylate, hydrolysis and caprylic acid formation starts immediately and was dependent on yeast density. ...
As shown by GC analysis with the reference strains CBS 1879 and CBS 1892 and 3-hydroxypropyl caprylate, hydrolysis and caprylic ac …
Enhanced Biofilm Eradication and Reduced Cytotoxicity of a Novel Polygalacturonic and Caprylic Acid Wound Ointment Compared with Common Antiseptic Ointments.
Gerges BZ, Rosenblatt J, Truong YL, Reitzel RA, Hachem R, Raad II. Gerges BZ, et al. Biomed Res Int. 2021 Feb 25;2021:2710484. doi: 10.1155/2021/2710484. eCollection 2021. Biomed Res Int. 2021. PMID: 33708989 Free PMC article.
Antiseptic wound ointments are widely used to treat dermal wounds that are microbially contaminated. Polygalacturonic acid (PG)+caprylic acid (CAP) is a novel combination that has been shown to eradicate biofilms. ...
Antiseptic wound ointments are widely used to treat dermal wounds that are microbially contaminated. Polygalacturonic acid (PG)+caprylic …
[Dietetic-therapeutic intervention in Candidiasis intestinal].
de la Casa Moreno I, Soriano del Castillo JM, Micó Pascual L. de la Casa Moreno I, et al. Nutr Hosp. 2014 Sep 1;30(3):686-9. doi: 10.3305/nh.2014.30.3.7620. Nutr Hosp. 2014. PMID: 25238848 Free article. Spanish.
BACKGROUND: Candidiasis are opportunistic yeast infections, the most common etiologic agent involved C.albicans creating problems at various levels. ...After evaluation proceeds to complement treatment with diet consisted in removal of simple sugars, yeast an …
BACKGROUND: Candidiasis are opportunistic yeast infections, the most common etiologic agent involved C.albicans creating probl …
Short- and medium-chain fatty acids exhibit antimicrobial activity for oral microorganisms.
Huang CB, Alimova Y, Myers TM, Ebersole JL. Huang CB, et al. Arch Oral Biol. 2011 Jul;56(7):650-4. doi: 10.1016/j.archoralbio.2011.01.011. Epub 2011 Feb 17. Arch Oral Biol. 2011. PMID: 21333271 Free PMC article.
METHODS: The short-chain fatty acids [formic acid (C1), acetic acid (C2), propionic acid (C3), butyric acid (C4), isobutyric acid (C4), isovaleric acid (C5), hexanoic acid (C6)], medium-chain fatty acids [octanoic acid (C8), capric acid (C10), lauric acid (12)], and …
METHODS: The short-chain fatty acids [formic acid (C1), acetic acid (C2), propionic acid (C3), butyric acid (C4), isobutyric acid (C4), isov …
Pilot Ex Vivo and In Vitro Evaluation of a Novel Foley Catheter with Antimicrobial Periurethral Irrigation for Prevention of Extraluminal Biofilm Colonization Leading to Catheter-Associated Urinary Tract Infections (CAUTIs).
Vargas-Cruz N, Rosenblatt J, Reitzel RA, Chaftari AM, Hachem R, Raad I. Vargas-Cruz N, et al. Biomed Res Int. 2019 Dec 23;2019:2869039. doi: 10.1155/2019/2869039. eCollection 2019. Biomed Res Int. 2019. PMID: 31976318 Free PMC article.
An in vitro biofilm colonization model was adapted to study the ability of periurethral irrigation with a newly developed antimicrobial combination consisting of polygalacturonic acid + caprylic acid (PG + CAP) to prevent axial colonization of the extraluminal ureth …
An in vitro biofilm colonization model was adapted to study the ability of periurethral irrigation with a newly developed antimicrobial comb …
[Inhibition of Candida mycelia growth by a medium chain fatty acids, capric acid in vitro and its therapeutic efficacy in murine oral candidiasis].
Takahashi M, Inoue S, Hayama K, Ninomiya K, Abe S. Takahashi M, et al. Med Mycol J. 2012;53(4):255-61. doi: 10.3314/mmj.53.255. Med Mycol J. 2012. PMID: 23257726 Free article. Japanese.
We assessed anti-C. albicans activities of the 4 fatty acids : caproic acid, caprylic acid, capric acid and lauric acid in vitro. All four inhibited not only the mycelial but also the yeast-form growth of Candida albicans. In particular, capric acid and ca …
We assessed anti-C. albicans activities of the 4 fatty acids : caproic acid, caprylic acid, capric acid and lauric acid in vit …
A Comparative Study of the Antimicrobial and Structural Properties of Short Peptides and Lipopeptides Containing a Repetitive Motif KLFK.
Húmpola MV, Rey MC, Spontón PG, Simonetta AC, Tonarelli GG. Húmpola MV, et al. Protein Pept Lett. 2019;26(3):192-203. doi: 10.2174/0929866526666181208144629. Protein Pept Lett. 2019. PMID: 30526450
METHODS: Minimal inhibitory concentration against Gram (+) and (-) bacteria and yeast of synthetic compounds were determined by broth microtiter dilution method, and the toxicity was evaluated by hemolysis assay. ...The (KLFK)3 peptide showed the highest therapeutic index …
METHODS: Minimal inhibitory concentration against Gram (+) and (-) bacteria and yeast of synthetic compounds were determined by broth …
Caprylate-thallous agar medium for selectively isolating Serratia and its utility in the clinical laboratory.
Starr MP, Grimont PA, Grimont F, Starr PB. Starr MP, et al. J Clin Microbiol. 1976 Sep;4(3):270-6. doi: 10.1128/jcm.4.3.270-276.1976. J Clin Microbiol. 1976. PMID: 972193 Free PMC article.
A defined agar medium (hereinafter designated caprylate-thallous [CT5 agar) containing 0.01% yeast extract, 0.1% caprylic (n-octanoic) acid, and 0.025% thallous sulfate is highly selective for all Serratia species and effectively discriminates against most no …
A defined agar medium (hereinafter designated caprylate-thallous [CT5 agar) containing 0.01% yeast extract, 0.1% caprylic (n-octan …
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