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Year Number of Results
2012 2
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2014 5
2015 8
2016 5
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Page 1
C-terminal agrin fragment as a biomarker of muscle wasting and weakness: a narrative review.
Monti E, Sarto F, Sartori R, Zanchettin G, Löfler S, Kern H, Narici MV, Zampieri S. Monti E, et al. J Cachexia Sarcopenia Muscle. 2023 Apr;14(2):730-744. doi: 10.1002/jcsm.13189. Epub 2023 Feb 11. J Cachexia Sarcopenia Muscle. 2023. PMID: 36772862 Free PMC article. Review.
To this aim, the reliability of easily accessible and non-invasive blood-derived biomarkers is being evaluated. C-terminal agrin fragment (CAF) has been widely investigated as a neuromuscular junction (NMJ)-related biomarker of muscle dysfunction. ...As agrin …
To this aim, the reliability of easily accessible and non-invasive blood-derived biomarkers is being evaluated. C-terminal agrin frag …
Effects of a 2-year exercise training on neuromuscular system health in older individuals with low muscle function.
Monti E, Tagliaferri S, Zampieri S, Sarto F, Sirago G, Franchi MV, Ticinesi A, Longobucco Y, Adorni E, Lauretani F, Von Haehling S, Marzetti E, Calvani R, Bernabei R, Cesari M, Maggio M, Narici MV. Monti E, et al. J Cachexia Sarcopenia Muscle. 2023 Apr;14(2):794-804. doi: 10.1002/jcsm.13173. Epub 2023 Jan 28. J Cachexia Sarcopenia Muscle. 2023. PMID: 36708273 Free PMC article. Clinical Trial.
As biomarkers of neuronal health and NMJ stability status, neurofilament light chain (NfL) and C-terminal agrin fragment (CAF) concentrations were measured in serum. Differences in ultrasound parameters, NfL and CAF concentration and physical performance betw …
As biomarkers of neuronal health and NMJ stability status, neurofilament light chain (NfL) and C-terminal agrin fragment (CAF) …
The C-Terminal Fragment of Agrin (CAF), a Novel Marker of Renal Function, Is Filtered by the Kidney and Reabsorbed by the Proximal Tubule.
Daryadel A, Haubitz M, Figueiredo M, Steubl D, Roos M, Mäder A, Hettwer S, Wagner CA. Daryadel A, et al. PLoS One. 2016 Jul 5;11(7):e0157905. doi: 10.1371/journal.pone.0157905. eCollection 2016. PLoS One. 2016. PMID: 27380275 Free PMC article.
Proteolytical activity of neurotrypsin produces a C-terminal fragment of agrin, termed CAF, of approximately 22 kDA molecular size which also circulates in blood. ...Thus, impaired kidney function could impair glomerular clearance of CAF and thereby increase …
Proteolytical activity of neurotrypsin produces a C-terminal fragment of agrin, termed CAF, of approximately 22 kDA molecular …
C-terminal fragment of agrin (CAF) levels predict acute kidney injury after acute myocardial infarction.
Arampatzis S, Chalikias G, Devetzis V, Konstantinides S, Huynh-Do U, Tziakas D. Arampatzis S, et al. BMC Nephrol. 2017 Jun 24;18(1):202. doi: 10.1186/s12882-017-0611-9. BMC Nephrol. 2017. PMID: 28646861 Free PMC article.
Novel biomarkers that can predict acute kidney injury in AMI may allow timely interventions. C-terminal fragment of agrin (CAF), a proteoglycan of the glomerular and tubular basement membrane, have been recently associated with rapid renal function deterioration and …
Novel biomarkers that can predict acute kidney injury in AMI may allow timely interventions. C-terminal fragment of agrin (CAF …
C-Terminal Fragment of Agrin (CAF): A Novel Marker for Progression of Kidney Disease in Type 2 Diabetics.
Devetzis V, Daryadel A, Roumeliotis S, Theodoridis M, Wagner CA, Hettwer S, Huynh-Do U, Ploumis P, Arampatzis S. Devetzis V, et al. PLoS One. 2015 Dec 2;10(12):e0143524. doi: 10.1371/journal.pone.0143524. eCollection 2015. PLoS One. 2015. PMID: 26630274 Free PMC article.
BACKGROUND: Diabetes is the leading cause of CKD in the developed world. C-terminal fragment of agrin (CAF) is a novel kidney function and injury biomarker. We investigated whether serum CAF predicts progression of kidney disease in type 2 diabetics. ...Corre …
BACKGROUND: Diabetes is the leading cause of CKD in the developed world. C-terminal fragment of agrin (CAF) is a novel kidney …
C-terminal agrin fragment (CAF) reflects renal function in patients suffering from severe sepsis or septic shock.
Drey M, Behnes M, Kob R, Lepiorz D, Hettwer S, Bollheimer C, Sieber CC, Bertsch T, Hoffmann U. Drey M, et al. Clin Lab. 2015;61(1-2):69-76. doi: 10.7754/clin.lab.2014.140724. Clin Lab. 2015. PMID: 25807640 Clinical Trial.
The identification of new biomarkers indicating the early development and future course of AKI are of utmost medical interest. The C-terminal agrin fragment (CAF) is measurable in blood serum and might reflect kidney function. ...Multiple linear regression analyses …
The identification of new biomarkers indicating the early development and future course of AKI are of utmost medical interest. The C-termina …
C-terminal agrin fragment (CAF) as a serum biomarker for residual renal function in peritoneal dialysis patients.
Steubl D, Hettwer S, Dahinden P, Luppa P, Rondak IC, Regenbogen C, Stock KF, Renders L, Heemann U, Roos M. Steubl D, et al. Int Urol Nephrol. 2015 Feb;47(2):391-6. doi: 10.1007/s11255-014-0852-5. Epub 2014 Oct 29. Int Urol Nephrol. 2015. PMID: 25352149
BACKGROUND: C-terminal agrin fragment (CAF, size 22 kDa) is a promising new biomarker for kidney function. ...RRF was inversely correlated with serum concentrations of CAF, cystatin c and creatinine being highest for CAF (r = -0.734, p = 0.007) followe …
BACKGROUND: C-terminal agrin fragment (CAF, size 22 kDa) is a promising new biomarker for kidney function. ...RRF was inversel …
Sarcopenia--The search for emerging biomarkers.
Kalinkovich A, Livshits G. Kalinkovich A, et al. Ageing Res Rev. 2015 Jul;22:58-71. doi: 10.1016/j.arr.2015.05.001. Epub 2015 May 8. Ageing Res Rev. 2015. PMID: 25962896 Review.
We hypothesize that the shift in this balance to muscle growth inhibitors, along with increased expression of the C- terminal agrin fragment (CAF) associated with age-dependent neuromuscular junction (NMJ) dysfunction, as well as skeletal muscle-specific troponin T …
We hypothesize that the shift in this balance to muscle growth inhibitors, along with increased expression of the C- terminal agrin f …
Circulating C-Terminal Agrin Fragment: A Potential Marker for Sarcopenia Among Type 2 Diabetes.
Racha P, Selvam S, Bose B, Bantwal G, Sambashivaiah S. Racha P, et al. Indian J Endocrinol Metab. 2022 Jul-Aug;26(4):334-340. doi: 10.4103/ijem.ijem_507_21. Epub 2022 Sep 20. Indian J Endocrinol Metab. 2022. PMID: 36185967 Free PMC article.
The feasibility of diagnosing sarcopenia in a clinical setup might be a difficult task. Circulating markers including C-terminal agrin fragment (CAF) are emerging as an alternative. Hence, the objectives of the study were to compare circulating CAF levels bet …
The feasibility of diagnosing sarcopenia in a clinical setup might be a difficult task. Circulating markers including C-terminal agrin …
Serum levels of C-terminal agrin fragment (CAF) are associated with sarcopenia in older hip fractured patients.
Marzetti E, Calvani R, Lorenzi M, Marini F, D'Angelo E, Martone AM, Celi M, Tosato M, Bernabei R, Landi F. Marzetti E, et al. Exp Gerontol. 2014 Dec;60:79-82. doi: 10.1016/j.exger.2014.10.003. Epub 2014 Oct 7. Exp Gerontol. 2014. PMID: 25304331
BACKGROUND: Serum concentrations of the C-terminal fragment of agrin (CAF), a component of the neuromuscular junction (NMJ), are elevated in older community-dwellers with sarcopenia. Whether CAF may be used as a marker for muscle wasting in the presence of NM …
BACKGROUND: Serum concentrations of the C-terminal fragment of agrin (CAF), a component of the neuromuscular junction (NMJ), a …
42 results