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RNA-sequencing reveals that STRN, ZNF484 and WNK1 add to the value of mitochondrial MT-COI and COX10 as markers of unstable coronary artery disease.
Holvoet P, Klocke B, Vanhaverbeke M, Menten R, Sinnaeve P, Raitoharju E, Lehtimäki T, Oksala N, Zinser C, Janssens S, Sipido K, Lyytikainen LP, Cagnin S. Holvoet P, et al. PLoS One. 2019 Dec 10;14(12):e0225621. doi: 10.1371/journal.pone.0225621. eCollection 2019. PLoS One. 2019. PMID: 31821324 Free PMC article.
RNA expressions in monocytes of MT-COI, COX10, STRN, WNK1 and ZNF484 were independent of cholesterol lowering and antiplatelet treatment. ...Expression of MT-COI, COX10, STRN and WNK1, but not that of ZNF484, PBMCs paired with that in monocytes. The prospective stud …
RNA expressions in monocytes of MT-COI, COX10, STRN, WNK1 and ZNF484 were independent of cholesterol lowering and antiplatelet treatm …
Study of Single Nucleotide Polymorphisms Associated with Breast Cancer Patients among Arab Ancestries.
Osman Y, Elsharkawy T, Hashim TM, Alratroot JA, Aljindan F, Almulla L, Alsuwat HS, Al Otaibi WM, Hegazi FM, Ibrahim AM, Borgio JF, AbdulAzeez S. Osman Y, et al. Int J Breast Cancer. 2022 Oct 11;2022:2442109. doi: 10.1155/2022/2442109. eCollection 2022. Int J Breast Cancer. 2022. PMID: 36268271 Free PMC article.
Successfully, we identified the most significant (p value 9.14 10(-09)) four associated SNPs [SNRK and SNRK-AS1-rs202018563G; BRCA2-rs2227943C; ZNF484-rs199826847C; and DCPS-rs1695739G] among persons with breast cancer versus the healthy controls even after Bonferroni corr …
Successfully, we identified the most significant (p value 9.14 10(-09)) four associated SNPs [SNRK and SNRK-AS1-rs202018563G; BRCA2-rs222794 …
Integration of protein interaction and gene co-expression information for identification of melanoma candidate genes.
Wu K, Wang W, Ye Y, Huang J, Zhou Y, Zhang Y, Zhang X, Wu W. Wu K, et al. Melanoma Res. 2019 Apr;29(2):126-133. doi: 10.1097/CMR.0000000000000525. Melanoma Res. 2019. PMID: 30451788
According to the network topology property of the putative genes, we selected seven key genes (CREB1, XPO1, SP3, TNFRSF1B, CD40LG, UBR1, and ZNF484) as candidate genes of melanoma. Subsequent analysis showed that six of these genes are melanoma-associated genes and one ( …
According to the network topology property of the putative genes, we selected seven key genes (CREB1, XPO1, SP3, TNFRSF1B, CD40LG, UBR1, and …
Identification of novel genes involved in apoptosis of HIV-infected macrophages using unbiased genome-wide screening.
Dong SXM, Vizeacoumar FS, Bhanumathy KK, Alli N, Gonzalez-Lopez C, Gajanayaka N, Caballero R, Ali H, Freywald A, Cassol E, Angel JB, Vizeacoumar FJ, Kumar A. Dong SXM, et al. BMC Infect Dis. 2021 Jul 7;21(1):655. doi: 10.1186/s12879-021-06346-7. BMC Infect Dis. 2021. PMID: 34233649 Free PMC article.
This culminated in the identification of four target genes, Cox7a2, Znf484, Cstf2t, and Cdk2, whose loss-of-function induced apoptosis preferentially in HIV-infected macrophages. ...
This culminated in the identification of four target genes, Cox7a2, Znf484, Cstf2t, and Cdk2, whose loss-of-function induced apoptosi …
Clustered DNA methylation changes in polycomb target genes in early-stage liver cancer.
Chen YL, Ko CJ, Lin PY, Chuang WL, Hsu CC, Chu PY, Pai MY, Chang CC, Kuo MH, Chu YR, Tung CH, Huang TH, Leu YW, Hsiao SH. Chen YL, et al. Biochem Biophys Res Commun. 2012 Aug 24;425(2):290-6. doi: 10.1016/j.bbrc.2012.07.084. Epub 2012 Jul 25. Biochem Biophys Res Commun. 2012. PMID: 22842566
To assess this, we examined the methylation states of four polycomb target loci -Trip10, Casp8AP2, ENSA, and ZNF484 - in liver cancer. These four targets were selected because their methylation levels are increased during mesenchymal stem cell-to-liver differentiation. ...
To assess this, we examined the methylation states of four polycomb target loci -Trip10, Casp8AP2, ENSA, and ZNF484 - in liver cancer …