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Deciphering Key Genes and miRNAs Associated With Hepatocellular Carcinoma via Network-Based Approach.
Bhatt S, Singh P, Sharma A, Rai A, Dohare R, Sankhwar S, Sharma A, Syed MA. Bhatt S, et al. IEEE/ACM Trans Comput Biol Bioinform. 2022 Mar-Apr;19(2):843-853. doi: 10.1109/TCBB.2020.3016781. Epub 2022 Apr 1. IEEE/ACM Trans Comput Biol Bioinform. 2022. PMID: 32795971
Thereafter, we identified the highly significant module of significant co-expressed genes and formed a PPI network for these genes. There were only six genes (namely, MSH3, DMC1, ALPP, IL10, ZNF223, and HSD17B7)obtained after analysis of the PPI network. Out of six only MS …
Thereafter, we identified the highly significant module of significant co-expressed genes and formed a PPI network for these genes. There we …
Sentinel Lymph Node Gene Expression Signature Predicts Recurrence-Free Survival in Cutaneous Melanoma.
Karapetyan L, Gooding W, Li A, Yang X, Knight A, Abushukair HM, Vargas De Stefano D, Sander C, Karunamurthy A, Panelli M, Storkus WJ, Tarhini AA, Kirkwood JM. Karapetyan L, et al. Cancers (Basel). 2022 Oct 11;14(20):4973. doi: 10.3390/cancers14204973. Cancers (Basel). 2022. PMID: 36291758 Free PMC article.
For the top 25 differentially expressed genes (DEG), 12 non-zero penalized coefficients were estimated (CLGN, C1QTNF3, ADORA3, ARHGAP8, DCTN1, ASPSCR1, CHRFAM7A, ZNF223, PDE6G, CXCL3, HEXIM1, HLA-DRB). This 12-gene signature score was significantly associated with RFS (p & …
For the top 25 differentially expressed genes (DEG), 12 non-zero penalized coefficients were estimated (CLGN, C1QTNF3, ADORA3, ARHGAP8, DCTN …
Chromosome 19 rearrangements in ovarian carcinomas: zinc finger genes are particularly targeted.
Smebye ML, Sveen A, Haugom L, Davidson B, Tropé CG, Lothe RA, Heim S, Skotheim RI, Micci F. Smebye ML, et al. Genes Chromosomes Cancer. 2014 Jul;53(7):558-67. doi: 10.1002/gcc.22166. Epub 2014 Mar 14. Genes Chromosomes Cancer. 2014. PMID: 24634323
The majority of these 39 genes of interest (n = 24, 62%) encode zinc finger proteins, which otherwise make up only 15% of the approximately 1,400 genes on chromosome 19. The strongest association was found for ZNF223 which was upregulated in samples with genomic gain compa …
The majority of these 39 genes of interest (n = 24, 62%) encode zinc finger proteins, which otherwise make up only 15% of the approximately …