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ZNF146/OZF and ZNF507 target LINE-1 sequences.
Creamer KM, Larsen EC, Lawrence JB. Creamer KM, et al. G3 (Bethesda). 2022 Mar 4;12(3):jkac002. doi: 10.1093/g3journal/jkac002. G3 (Bethesda). 2022. PMID: 35100360 Free PMC article.
We show 2 of the proteins identified, C2H2 zinc finger-containing proteins ZNF146 (also known as OZF) and ZNF507, are targeted to distinct sites within LINE-1 ORF2 at thousands of locations in the genome. ZNF146 binding sites are found at old and young LINE-1 elemen …
We show 2 of the proteins identified, C2H2 zinc finger-containing proteins ZNF146 (also known as OZF) and ZNF507, are targeted to dis …
Long Noncoding RNA ZBED5-AS1 Facilitates Tumor Progression and Metastasis in Lung Adenocarcinoma via ZNF146/ATR/Chk1 Axis.
Jiang F, Huang X, Ling L, Tang S, Zhou H, Cai X, Wang Y. Jiang F, et al. Int J Mol Sci. 2023 Sep 10;24(18):13925. doi: 10.3390/ijms241813925. Int J Mol Sci. 2023. PMID: 37762228 Free PMC article.
ZBED5-AS1 promoted LUAD cell proliferation, migration, and invasion in vitro and promoted LUAD cell growth in vivo. ZBED5-AS1 promoted ZNF146 expression, activating the ATR/Chk1 pathway and leading to LUAD progression. ...Our results indicate that ZBED5-AS1 functions as an …
ZBED5-AS1 promoted LUAD cell proliferation, migration, and invasion in vitro and promoted LUAD cell growth in vivo. ZBED5-AS1 promoted ZN …
CircPIP5K1A facilitates gastric cancer progression via miR-376c-3p/ZNF146 axis.
Ma Y, Cong X, Zhang Y, Yin X, Zhu Z, Xue Y. Ma Y, et al. Cancer Cell Int. 2020 Mar 14;20:81. doi: 10.1186/s12935-020-1122-5. eCollection 2020. Cancer Cell Int. 2020. PMID: 32190005 Free PMC article.
Follow-up mechanism tests unveiled that circPIP5K1A bound with miR-376c-3p and inhibition of miR-376c-3p reversed circPIP5K1A downregulation-mediated effect on GC progression. Additionally, ZNF146 was verified to be the downstream molecule of circPIP5K1A/miR-376c-3p axis i …
Follow-up mechanism tests unveiled that circPIP5K1A bound with miR-376c-3p and inhibition of miR-376c-3p reversed circPIP5K1A downregulation …
ZNF146 regulates cell cycle progression via TFDP1 and DEPDC1B in ovarian cancer cells.
Zhao R, Song N, Ning X, Chen X, Ma R. Zhao R, et al. Reproduction. 2024 Apr 1:REP-23-0484. doi: 10.1530/REP-23-0484. Online ahead of print. Reproduction. 2024. PMID: 38614125
Silencing of TFDP1 inhibited the biological activity of OC cells and hindered cell cycle entry. Zinc finger protein 146 (ZNF146) knockdown induced cell cycle arrest at the G0/G1 phase and tumor growth by blocking TFDP1 transcription, which was overturned by ectopic express …
Silencing of TFDP1 inhibited the biological activity of OC cells and hindered cell cycle entry. Zinc finger protein 146 (ZNF146) knoc …
Hsa_circ_NOTCH3 regulates ZNF146 through sponge adsorption of miR-875-5p to promote tumorigenesis of hepatocellular carcinoma.
Bao L, Wang M, Fan Q. Bao L, et al. J Gastrointest Oncol. 2021 Oct;12(5):2388-2402. doi: 10.21037/jgo-21-567. J Gastrointest Oncol. 2021. PMID: 34790400 Free PMC article.
In terms of mechanism, circ_NOTCH3 directly binds to miR-875-5p, regulating its activity by targeting the 3'-UTR of ZNF146. Overexpression of circ_NOTCH3 evidently overturned the diminishing influence of miR-875-5p mimics on HCC cells. CONCLUSIONS: As an oncogene, circ_NOT …
In terms of mechanism, circ_NOTCH3 directly binds to miR-875-5p, regulating its activity by targeting the 3'-UTR of ZNF146. Overexpre …
LncRNA KCNQ1OT1 acts as miR-216b-5p sponge to promote colorectal cancer progression via up-regulating ZNF146.
Zhu S, Chen CY, Hao Y. Zhu S, et al. J Mol Histol. 2021 Jun;52(3):479-490. doi: 10.1007/s10735-020-09942-0. Epub 2021 Jan 4. J Mol Histol. 2021. PMID: 33394291
KCNQ1OT1 up-regulated the abundance of ZNF146 through sequestering miR-216b-5p in CRC cells. KCNQ1OT1 accelerated the proliferation and motility of CRC cells through elevating ZNF146 expression via sponging miR-216b-5p. KCNQ1OT1/miR-216b-5p/ZNF146 axis might …
KCNQ1OT1 up-regulated the abundance of ZNF146 through sequestering miR-216b-5p in CRC cells. KCNQ1OT1 accelerated the proliferation a …
Localization of ZNF164, ZNF146, GGTA1, SOX2, PRLR and EEF2 on homoeologous cattle, sheep and goat chromosomes by fluorescent in situ hybridization and comparison with the human gene map.
Hayes H, Le Chalony C, Goubin G, Mercier D, Payen E, Bignon C, Kohno K. Hayes H, et al. Cytogenet Cell Genet. 1996;72(4):342-6. doi: 10.1159/000134218. Cytogenet Cell Genet. 1996. PMID: 8641144
The six following genes: zinc finger proteins 164 (ZNF164) and 146 (ZNF146), alpha-galactosyltransferase 1 (GGTA1), SRY-related HMG-box 2 (SOX2), prolactin receptor (PRLR) and elongatin factor 2 (EEF2) have been localized by fluorescent in situ hybridization respectively o …
The six following genes: zinc finger proteins 164 (ZNF164) and 146 (ZNF146), alpha-galactosyltransferase 1 (GGTA1), SRY-related HMG-b …
Cloning, characterization, and chromosome assignment of Zfp146 the mouse ortholog of human ZNF146, a gene amplified and overexpressed in pancreatic cancer, and Zfp260 a closely related gene.
Blottière L, Apiou F, Ferbus D, Guenzi C, Dutrillaux B, Prospéri MT, Goubin G. Blottière L, et al. Cytogenet Cell Genet. 1999;85(3-4):297-300. doi: 10.1159/000015316. Cytogenet Cell Genet. 1999. PMID: 10449921
The human OZF gene (ZNF146), located in chromosome band 19q13.1, is amplified and overexpressed in pancreatic carcinomas. ...
The human OZF gene (ZNF146), located in chromosome band 19q13.1, is amplified and overexpressed in pancreatic carcinomas. ...
Genomic organization and promoter identification of ZNF146, a gene encoding a protein consisting solely of zinc finger domains.
Pibouin L, Villaudy J, Prospéri MT, Goubin G. Pibouin L, et al. Cytogenet Cell Genet. 2001;92(1-2):80-4. doi: 10.1159/000056873. Cytogenet Cell Genet. 2001. PMID: 11306801
The ZNF146 gene (alias OZF) encodes a protein consisting solely of ten zinc finger motifs. ...ZNF146 encompasses 25 kb of sequence and consists of four non-coding exons located upstream of a single coding exon. ...
The ZNF146 gene (alias OZF) encodes a protein consisting solely of ten zinc finger motifs. ...ZNF146 encompasses 25 kb of sequ …
25 results