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Items: 10


Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells.

Dhar SS, Alam H, Li N, Wagner KW, Chung J, Ahn YW, Lee MG.

J Biol Chem. 2014 Mar 14;289(11):7483-96. doi: 10.1074/jbc.M113.521625. Epub 2014 Jan 30.


KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling.

Wagner KW, Alam H, Dhar SS, Giri U, Li N, Wei Y, Giri D, Cascone T, Kim JH, Ye Y, Multani AS, Chan CH, Erez B, Saigal B, Chung J, Lin HK, Wu X, Hung MC, Heymach JV, Lee MG.

J Clin Invest. 2013 Dec;123(12):5231-46. doi: 10.1172/JCI68642. Epub 2013 Nov 8.


Genetic variations in epigenetic genes are predictors of recurrence in stage I or II non-small cell lung cancer patients.

Wagner KW, Ye Y, Lin J, Vaporciyan AA, Roth JA, Wu X.

Clin Cancer Res. 2012 Jan 15;18(2):585-92. doi: 10.1158/1078-0432.CCR-11-2087.


Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.

Wagner KW, Punnoose EA, Januario T, Lawrence DA, Pitti RM, Lancaster K, Lee D, von Goetz M, Yee SF, Totpal K, Huw L, Katta V, Cavet G, Hymowitz SG, Amler L, Ashkenazi A.

Nat Med. 2007 Sep;13(9):1070-7. Epub 2007 Sep 2.


Diplopia and acute rectus muscle palsy as symptoms of an infected follicular cyst of a maxillary right third molar: a case report.

Metzger MC, Wagner KW, Hohlweg-Majert B, Voss PJ, Schoen R, Schmelzeisen R.

Quintessence Int. 2007 Jul-Aug;38(7):571-4.


Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle.

Ren YG, Wagner KW, Knee DA, Aza-Blanc P, Nasoff M, Deveraux QL.

Mol Biol Cell. 2004 Nov;15(11):5064-74. Epub 2004 Sep 8.


Overexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic origin.

Wagner KW, Sapinoso LM, El-Rifai W, Frierson HF, Butz N, Mestan J, Hofmann F, Deveraux QL, Hampton GM.

Oncogene. 2004 Aug 26;23(39):6621-9.


Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway.

Wagner KW, Engels IH, Deveraux QL.

J Biol Chem. 2004 Aug 13;279(33):35047-52. Epub 2004 Jun 1.


Activation and suppression of the TRAIL death-receptor pathway in chemotherapy sensitive and resistant follicular lymphoma cells.

Wagner KW, King F, Nomoto K, Knee DA, Hampton G, Nasoff M, Deveraux QL.

Cancer Biol Ther. 2003 Sep-Oct;2(5):534-40.


Exposing oncogenic dependencies for cancer drug target discovery and validation using RNAi.

Deveraux QL, Aza-Blanc P, Wagner KW, Bauerschlag D, Cooke MP, Hampton GM.

Semin Cancer Biol. 2003 Aug;13(4):293-300. Review.

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