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Transcriptome-wide modulation of splicing by the exon junction complex.
Wang Z, Murigneux V, Le Hir H. Wang Z, et al. Genome Biol. 2014;15(12):551. doi: 10.1186/s13059-014-0551-7. Genome Biol. 2014. PMID: 25476502 Free PMC article.
BACKGROUND: The exon junction complex (EJC) is a dynamic multi-protein complex deposited onto nuclear spliced mRNAs upstream of exon-exon junctions. ...Finally, we find that the splicing changes are linked with RNA …
BACKGROUND: The exon junction complex (EJC) is a dynamic multi-protein complex deposited onto nuclear spliced …
Dynamic nanopore long-read sequencing analysis of HIV-1 splicing events during the early steps of infection.
Nguyen Quang N, Goudey S, Ségéral E, Mohammad A, Lemoine S, Blugeon C, Versapuech M, Paillart JC, Berlioz-Torrent C, Emiliani S, Gallois-Montbrun S. Nguyen Quang N, et al. Retrovirology. 2020 Aug 17;17(1):25. doi: 10.1186/s12977-020-00533-1. Retrovirology. 2020. PMID: 32807178 Free PMC article.
Understanding the mechanisms involved in the regulation of viral RNA is therefore of potential therapeutic interest. However, monitoring the regulation of alternative splicing events at a transcriptome-wide level during cell infection is challenging. . …
Understanding the mechanisms involved in the regulation of viral RNA is therefore of potential therapeutic interest. However, monitor …