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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1993 1
1996 1
1997 1
2000 1
2001 3
2002 2
2004 1
2007 3
2008 1
2009 3
2010 6
2011 2
2012 1
2013 1
2019 1
2020 2
2021 3
2022 1
2024 0

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31 results

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Page 1
Discovery and Pharmacological Characterization of JNJ-64619178, a Novel Small-Molecule Inhibitor of PRMT5 with Potent Antitumor Activity.
Brehmer D, Beke L, Wu T, Millar HJ, Moy C, Sun W, Mannens G, Pande V, Boeckx A, van Heerde E, Nys T, Gustin EM, Verbist B, Zhou L, Fan Y, Bhargava V, Safabakhsh P, Vinken P, Verhulst T, Gilbert A, Rai S, Graubert TA, Pastore F, Fiore D, Gu J, Johnson A, Philippar U, Morschhäuser B, Walker D, De Lange D, Keersmaekers V, Viellevoye M, Diels G, Schepens W, Thuring JW, Meerpoel L, Packman K, Lorenzi MV, Laquerre S. Brehmer D, et al. Among authors: thuring jw. Mol Cancer Ther. 2021 Dec;20(12):2317-2328. doi: 10.1158/1535-7163.MCT-21-0367. Epub 2021 Sep 28. Mol Cancer Ther. 2021. PMID: 34583982 Free PMC article.
Synthesis of 3-amino-4-fluoropyrazoles.
Surmont R, Verniest G, De Schrijver M, Thuring JW, ten Holte P, Deroose F, De Kimpe N. Surmont R, et al. Among authors: thuring jw. J Org Chem. 2011 May 20;76(10):4105-11. doi: 10.1021/jo2000989. Epub 2011 Apr 29. J Org Chem. 2011. PMID: 21500813
Synthesis of 4-substituted 3,3-difluoropiperidines.
Surmont R, Verniest G, Thuring JW, Macdonald G, Deroose F, De Kimpe N. Surmont R, et al. Among authors: thuring jw. J Org Chem. 2010 Feb 5;75(3):929-32. doi: 10.1021/jo902164z. J Org Chem. 2010. PMID: 20050617
Synthesis of 1-Boc-3-fluoroazetidine-3-carboxylic acid.
Van Hende E, Verniest G, Deroose F, Thuring JW, Macdonald G, De Kimpe N. Van Hende E, et al. Among authors: thuring jw. J Org Chem. 2009 Mar 6;74(5):2250-3. doi: 10.1021/jo802791r. J Org Chem. 2009. PMID: 19216497
New synthesis of 3-fluoropyrroles.
Surmont R, Verniest G, Colpaert F, Macdonald G, Thuring JW, Deroose F, De Kimpe N. Surmont R, et al. Among authors: thuring jw. J Org Chem. 2009 Feb 6;74(3):1377-80. doi: 10.1021/jo802272n. J Org Chem. 2009. PMID: 19115927
A Chemical Probe for the Methyl Transferase PRMT5 with a Novel Binding Mode.
Pande V, Sun W, Beke L, Berthelot D, Brehmer D, Brown D, Corbera J, Irving S, Meerpoel L, Nys T, Parade M, Robinson C, Sommen C, Viellevoye M, Wu T, Thuring JW. Pande V, et al. Among authors: thuring jw. ACS Med Chem Lett. 2020 Sep 28;11(11):2227-2231. doi: 10.1021/acsmedchemlett.0c00355. eCollection 2020 Nov 12. ACS Med Chem Lett. 2020. PMID: 33214833 Free PMC article.
31 results