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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1947 2
1948 1
1972 1
1974 1
1975 1
1980 1
1981 1
1982 1
1983 1
1985 1
1986 1
1987 1
1989 1
1991 1
1992 2
1993 2
1994 4
1995 2
1996 1
1997 7
1998 7
1999 7
2000 2
2001 2
2002 5
2003 6
2004 4
2005 5
2006 9
2007 11
2008 7
2009 6
2010 9
2011 9
2012 12
2013 19
2014 16
2015 11
2016 20
2017 10
2018 14
2019 17
2020 15
2021 6
2022 11
2023 15
2024 7

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276 results

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Page 1
Loss of epigenetic information as a cause of mammalian aging.
Yang JH, Hayano M, Griffin PT, Amorim JA, Bonkowski MS, Apostolides JK, Salfati EL, Blanchette M, Munding EM, Bhakta M, Chew YC, Guo W, Yang X, Maybury-Lewis S, Tian X, Ross JM, Coppotelli G, Meer MV, Rogers-Hammond R, Vera DL, Lu YR, Pippin JW, Creswell ML, Dou Z, Xu C, Mitchell SJ, Das A, O'Connell BL, Thakur S, Kane AE, Su Q, Mohri Y, Nishimura EK, Schaevitz L, Garg N, Balta AM, Rego MA, Gregory-Ksander M, Jakobs TC, Zhong L, Wakimoto H, El Andari J, Grimm D, Mostoslavsky R, Wagers AJ, Tsubota K, Bonasera SJ, Palmeira CM, Seidman JG, Seidman CE, Wolf NS, Kreiling JA, Sedivy JM, Murphy GF, Green RE, Garcia BA, Berger SL, Oberdoerffer P, Shankland SJ, Gladyshev VN, Ksander BR, Pfenning AR, Rajman LA, Sinclair DA. Yang JH, et al. Among authors: sinclair da. Cell. 2023 Jan 19;186(2):305-326.e27. doi: 10.1016/j.cell.2022.12.027. Epub 2023 Jan 12. Cell. 2023. PMID: 36638792 Free PMC article.
Chemically induced reprogramming to reverse cellular aging.
Yang JH, Petty CA, Dixon-McDougall T, Lopez MV, Tyshkovskiy A, Maybury-Lewis S, Tian X, Ibrahim N, Chen Z, Griffin PT, Arnold M, Li J, Martinez OA, Behn A, Rogers-Hammond R, Angeli S, Gladyshev VN, Sinclair DA. Yang JH, et al. Among authors: sinclair da. Aging (Albany NY). 2023 Jul 12;15(13):5966-5989. doi: 10.18632/aging.204896. Epub 2023 Jul 12. Aging (Albany NY). 2023. PMID: 37437248 Free PMC article.
Mitochondrial and metabolic dysfunction in ageing and age-related diseases.
Amorim JA, Coppotelli G, Rolo AP, Palmeira CM, Ross JM, Sinclair DA. Amorim JA, et al. Among authors: sinclair da. Nat Rev Endocrinol. 2022 Apr;18(4):243-258. doi: 10.1038/s41574-021-00626-7. Epub 2022 Feb 10. Nat Rev Endocrinol. 2022. PMID: 35145250 Free PMC article. Review.
Human trials exploring anti-aging medicines.
Guarente L, Sinclair DA, Kroemer G. Guarente L, et al. Among authors: sinclair da. Cell Metab. 2024 Feb 6;36(2):354-376. doi: 10.1016/j.cmet.2023.12.007. Epub 2024 Jan 4. Cell Metab. 2024. PMID: 38181790 Review.
Reprogramming to recover youthful epigenetic information and restore vision.
Lu Y, Brommer B, Tian X, Krishnan A, Meer M, Wang C, Vera DL, Zeng Q, Yu D, Bonkowski MS, Yang JH, Zhou S, Hoffmann EM, Karg MM, Schultz MB, Kane AE, Davidsohn N, Korobkina E, Chwalek K, Rajman LA, Church GM, Hochedlinger K, Gladyshev VN, Horvath S, Levine ME, Gregory-Ksander MS, Ksander BR, He Z, Sinclair DA. Lu Y, et al. Among authors: sinclair da. Nature. 2020 Dec;588(7836):124-129. doi: 10.1038/s41586-020-2975-4. Epub 2020 Dec 2. Nature. 2020. PMID: 33268865 Free PMC article.
Human age reversal: Fact or fiction?
Johnson AA, English BW, Shokhirev MN, Sinclair DA, Cuellar TL. Johnson AA, et al. Among authors: sinclair da. Aging Cell. 2022 Aug;21(8):e13664. doi: 10.1111/acel.13664. Epub 2022 Jul 2. Aging Cell. 2022. PMID: 35778957 Free PMC article. Review.
The Information Theory of Aging.
Lu YR, Tian X, Sinclair DA. Lu YR, et al. Among authors: sinclair da. Nat Aging. 2023 Dec;3(12):1486-1499. doi: 10.1038/s43587-023-00527-6. Epub 2023 Dec 15. Nat Aging. 2023. PMID: 38102202 Review.
The intersection between aging and cardiovascular disease.
North BJ, Sinclair DA. North BJ, et al. Among authors: sinclair da. Circ Res. 2012 Apr 13;110(8):1097-108. doi: 10.1161/CIRCRESAHA.111.246876. Circ Res. 2012. PMID: 22499900 Free PMC article. Review.
NAD+ in Brain Aging and Neurodegenerative Disorders.
Lautrup S, Sinclair DA, Mattson MP, Fang EF. Lautrup S, et al. Among authors: sinclair da. Cell Metab. 2019 Oct 1;30(4):630-655. doi: 10.1016/j.cmet.2019.09.001. Cell Metab. 2019. PMID: 31577933 Free PMC article. Review.
Epigenetic changes during aging and their reprogramming potential.
Kane AE, Sinclair DA. Kane AE, et al. Among authors: sinclair da. Crit Rev Biochem Mol Biol. 2019 Feb;54(1):61-83. doi: 10.1080/10409238.2019.1570075. Epub 2019 Mar 1. Crit Rev Biochem Mol Biol. 2019. PMID: 30822165 Free PMC article. Review.
276 results