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64 results

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ARS2/SRRT: at the nexus of RNA polymerase II transcription, transcript maturation and quality control.
Lykke-Andersen S, Rouvière JO, Jensen TH. Lykke-Andersen S, et al. Biochem Soc Trans. 2021 Jun 30;49(3):1325-1336. doi: 10.1042/BST20201008. Biochem Soc Trans. 2021. PMID: 34060620 Review.
ARS2/SRRT is an essential eukaryotic protein that has emerged as a critical factor in the sorting of functional from non-functional RNA polymerase II (Pol II) transcripts. ...The central position of the protein within the nuclear gene expression machinery likely explains w …
ARS2/SRRT is an essential eukaryotic protein that has emerged as a critical factor in the sorting of functional from non-functional R …
The landscape of genetic diseases in Saudi Arabia based on the first 1000 diagnostic panels and exomes.
Monies D, Abouelhoda M, AlSayed M, Alhassnan Z, Alotaibi M, Kayyali H, Al-Owain M, Shah A, Rahbeeni Z, Al-Muhaizea MA, Alzaidan HI, Cupler E, Bohlega S, Faqeih E, Faden M, Alyounes B, Jaroudi D, Goljan E, Elbardisy H, Akilan A, Albar R, Aldhalaan H, Gulab S, Chedrawi A, Al Saud BK, Kurdi W, Makhseed N, Alqasim T, El Khashab HY, Al-Mousa H, Alhashem A, Kanaan I, Algoufi T, Alsaleem K, Basha TA, Al-Murshedi F, Khan S, Al-Kindy A, Alnemer M, Al-Hajjar S, Alyamani S, Aldhekri H, Al-Mehaidib A, Arnaout R, Dabbagh O, Shagrani M, Broering D, Tulbah M, Alqassmi A, Almugbel M, AlQuaiz M, Alsaman A, Al-Thihli K, Sulaiman RA, Al-Dekhail W, Alsaegh A, Bashiri FA, Qari A, Alhomadi S, Alkuraya H, Alsebayel M, Hamad MH, Szonyi L, Abaalkhail F, Al-Mayouf SM, Almojalli H, Alqadi KS, Elsiesy H, Shuaib TM, Seidahmed MZ, Abosoudah I, Akleh H, AlGhonaium A, Alkharfy TM, Al Mutairi F, Eyaid W, Alshanbary A, Sheikh FR, Alsohaibani FI, Alsonbul A, Al Tala S, Balkhy S, Bassiouni R, Alenizi AS, Hussein MH, Hassan S, Khalil M, Tabarki B, Alshahwan S, Oshi A, Sabr Y, Alsaadoun S, Salih MA, Mohamed S, Sultana H, Tamim A, El-Haj M, Alshahrani S, Bubshait DK, Alfadhel M, Faquih T, El-Kalioby M, Subhani S, Shah … See abstract for full author list ➔ Monies D, et al. Hum Genet. 2017 Aug;136(8):921-939. doi: 10.1007/s00439-017-1821-8. Epub 2017 Jun 9. Hum Genet. 2017. PMID: 28600779 Free PMC article.
Finally, we have encountered candidate variants in 75 genes (ABHD6, ACY3, ADGRB2, ADGRG7, AGTPBP1, AHNAK2, AKAP6, ASB3, ATXN1L, C17orf62, CABP1, CCDC186, CCP110, CLSTN2, CNTN3, CNTN5, CTNNA2, CWC22, DMAP1, DMKN, DMXL1, DSCAM, DVL2, ECI1, EP400, EPB41L5, FBXL22, GAP43, GEMIN7, GIT …
Finally, we have encountered candidate variants in 75 genes (ABHD6, ACY3, ADGRB2, ADGRG7, AGTPBP1, AHNAK2, AKAP6, ASB3, ATXN1L, C17orf62, CA …
Serrate RNA Effector Molecule (SRRT) Is Associated with Prostate Cancer Progression and Is a Predictor of Poor Prognosis in Lethal Prostate Cancer.
Gamallat Y, Choudhry M, Li Q, Rokne JG, Alhajj R, Abdelsalam R, Ghosh S, Arbet J, Boutros PC, Bismar TA. Gamallat Y, et al. Cancers (Basel). 2023 May 22;15(10):2867. doi: 10.3390/cancers15102867. Cancers (Basel). 2023. PMID: 37345203 Free PMC article.
Arsenite-resistance protein 2, also known as serrate RNA effector molecule (ARS2/SRRT), is known to be involved in cellular proliferation and tumorigenicity. ...We also explored the association of SRRT with common genetic aberrations in lethal PCa using immunohistoc …
Arsenite-resistance protein 2, also known as serrate RNA effector molecule (ARS2/SRRT), is known to be involved in cellular prolifera …
Efficacy and safety of rivaroxaban in extreme elderly patients with atrial fibrillation: Analysis of the Shikoku Rivaroxaban Registry Trial (SRRT).
Bando S, Nishikado A, Hiura N, Ikeda S, Kakutani A, Yamamoto K, Kaname N, Fukatani M, Takagi Y, Yukiiri K, Fukuda Y, Nakaya Y. Bando S, et al. J Cardiol. 2018 Feb;71(2):197-201. doi: 10.1016/j.jjcc.2017.08.005. Epub 2017 Sep 29. J Cardiol. 2018. PMID: 28969968 Free article.
BACKGROUND: The Shikoku Rivaroxaban Registry Trial (SRRT) is a retrospective survey of the use of rivaroxaban for stroke prevention in elderly patients in Shikoku, Japan. METHODS: The SRRT enrolled 1339 patients from 8 hospitals. Patients were divided into two group …
BACKGROUND: The Shikoku Rivaroxaban Registry Trial (SRRT) is a retrospective survey of the use of rivaroxaban for stroke prevention i …
A transcriptome-wide antitermination mechanism sustaining identity of embryonic stem cells.
Kainov YA, Makeyev EV. Kainov YA, et al. Nat Commun. 2020 Jan 17;11(1):361. doi: 10.1038/s41467-019-14204-z. Nat Commun. 2020. PMID: 31953406 Free PMC article.
Srrt interacts with the nuclear cap-binding complex and facilitates recruitment of the spliceosome component U1 snRNP to cognate intronic positions. ...Our work identifies Srrt as a molecular guardian of the pluripotent cell state....
Srrt interacts with the nuclear cap-binding complex and facilitates recruitment of the spliceosome component U1 snRNP to cognate intr …
Interactome-transcriptome analysis discovers signatures complementary to GWAS Loci of Type 2 Diabetes.
Li JW, Lee HM, Wang Y, Tong AH, Yip KY, Tsui SK, Lok S, Ozaki R, Luk AO, Kong AP, So WY, Ma RC, Chan JC, Chan TF. Li JW, et al. Sci Rep. 2016 Oct 18;6:35228. doi: 10.1038/srep35228. Sci Rep. 2016. PMID: 27752041 Free PMC article.
The T2Di revealed a novel locus near a well-established GWAS loci AChE, in which SRRT interacts with JAZF1, a T2D-GWAS gene implicated in pancreatic function. ...These T2Di signatures were validated by an independent computational method, and by expression data of pancreat …
The T2Di revealed a novel locus near a well-established GWAS loci AChE, in which SRRT interacts with JAZF1, a T2D-GWAS gene implicate …
PSMC2, ORC5 and KRTDAP are specific biomarkers for HPV-negative head and neck squamous cell carcinoma.
Su Y, Zeng Z, Rong D, Yang Y, Wu B, Cao Y. Su Y, et al. Oncol Lett. 2021 Apr;21(4):289. doi: 10.3892/ol.2021.12550. Epub 2021 Feb 12. Oncol Lett. 2021. PMID: 33732365 Free PMC article.
The diagnostic value of the hub genes associated with HPV-negative and HPV-positive HNSCC was analyzed using differential expression gene (DEG) analysis, immunohistochemical (IHC) staining and a receiver operating characteristic (ROC) curve analysis. Seven genes [Serrate RNA effe …
The diagnostic value of the hub genes associated with HPV-negative and HPV-positive HNSCC was analyzed using differential expression gene (D …
Development of the Electronic Surveillance Monitoring System on Web Applications.
Soontornpipit P, Viwatwongkasem C, Taratep C, Teerawat W, Vanitchatchavan P. Soontornpipit P, et al. Procedia Comput Sci. 2016;86:244-247. doi: 10.1016/j.procs.2016.05.110. Epub 2016 May 24. Procedia Comput Sci. 2016. PMID: 32288901 Free PMC article.
The system is created for three purposes, the alert function for the surveillance and rapid response team (SRRT), the monitoring for inspection and evaluation, and the back-office report. ...The program is designed to submit reports automatically to the Ministry of Public …
The system is created for three purposes, the alert function for the surveillance and rapid response team (SRRT), the monitoring for …
Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators.
Scheibe M, Arnoult N, Kappei D, Buchholz F, Decottignies A, Butter F, Mann M. Scheibe M, et al. Genome Res. 2013 Dec;23(12):2149-57. doi: 10.1101/gr.151878.112. Epub 2013 Aug 6. Genome Res. 2013. PMID: 23921659 Free PMC article.
Knockdown of 10 genes encoding candidate proteins significantly affected total cellular levels of TERRA, and RNAi of five candidates perturbed TERRA recruitment to telomeres. Notably, depletion of SRRT/ARS2, involved in miRNA processing, up-regulated both total and telomer …
Knockdown of 10 genes encoding candidate proteins significantly affected total cellular levels of TERRA, and RNAi of five candidates perturb …
64 results