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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1928 1
1959 1
1963 2
1964 1
1966 1
1970 1
1972 10
1973 2
1974 3
1975 5
1976 4
1977 7
1978 9
1979 2
1980 6
1981 3
1982 10
1983 4
1984 3
1985 11
1986 8
1987 11
1988 16
1989 15
1990 22
1991 22
1992 25
1993 18
1994 24
1995 14
1996 38
1997 27
1998 34
1999 56
2000 82
2001 88
2002 80
2003 117
2004 133
2005 165
2006 194
2007 236
2008 273
2009 270
2010 352
2011 415
2012 471
2013 582
2014 681
2015 685
2016 672
2017 698
2018 707
2019 749
2020 920
2021 1224
2022 1478
2023 1630
2024 560

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11,971 results

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Page 1
Applications of low-flow LC-SRM for the analysis of large molecules in pharmaceutical R&D.
Lassman ME, Fernandez-Metzler C. Lassman ME, et al. Bioanalysis. 2014;6(13):1859-67. doi: 10.4155/bio.14.141. Bioanalysis. 2014. PMID: 25157490 Review.
Although ligand-binding assays are frequently employed to measure large molecules, the use of LC-SRM assays is increasingly popular due to the inherent selectivity advantage and the ability to operate without exquisitely selective antibodies. Until recently LC-SRM a …
Although ligand-binding assays are frequently employed to measure large molecules, the use of LC-SRM assays is increasingly popular d …
LC-SRM-Based Targeted Quantification of Urinary Protein Biomarkers.
Gao Y, Wang H, Nicora CD, Shi T, Smith RD, Sigdel TK, Sarwal MM, Camp DG 2nd, Qian WJ. Gao Y, et al. Methods Mol Biol. 2018;1788:145-156. doi: 10.1007/7651_2017_93. Methods Mol Biol. 2018. PMID: 29116567 Free PMC article.
Liquid chromatography (LC)-selected reaction monitoring (SRM) is a powerful protein quantification technique in terms of sensitivity, reproducibility, and multiplexing capability. ...Herein, we describe a step-by-step protocol of the application of LC-SRM to quantif …
Liquid chromatography (LC)-selected reaction monitoring (SRM) is a powerful protein quantification technique in terms of sensitivity, …
Bleaching-Resistant Super-Resolution Fluorescence Microscopy.
Kwon J, Elgawish MS, Shim SH. Kwon J, et al. Adv Sci (Weinh). 2022 Mar;9(9):e2101817. doi: 10.1002/advs.202101817. Epub 2022 Jan 27. Adv Sci (Weinh). 2022. PMID: 35088584 Free PMC article. Review.
Strategies for preventing or overcoming photobleaching in SRM are reviewed developing new probes and chemical environments. Photostabilization strategies are introduced first, which are borrowed from conventional fluorescence microscopy, that are employed in SRM. …
Strategies for preventing or overcoming photobleaching in SRM are reviewed developing new probes and chemical environments. Photostab …
The development of SRM assays is transforming proteomics research.
Manes NP, Nita-Lazar A. Manes NP, et al. Proteomics. 2017 Apr;17(7). doi: 10.1002/pmic.201600366. Epub 2016 Nov 30. Proteomics. 2017. PMID: 27718317
Bottom-up targeted proteomics using SRM is a powerful analytical technology, but it requires the development of SRM assays, which is a complex procedure. Whereas proteome-wide SRM assays have recently been developed for a small number of species, this is not …
Bottom-up targeted proteomics using SRM is a powerful analytical technology, but it requires the development of SRM assays, wh …
[p SRM, SWATH and HRM - targeted proteomics approaches on TripleTOF 5600+ mass spectrometer and their applications in oncology research].
Faktor J, Michalova E, Bouchal P. Faktor J, et al. Klin Onkol. 2014;27 Suppl 1:S110-5. doi: 10.14735/amko20141s110. Klin Onkol. 2014. PMID: 24945547 Review. Czech.
Novel quantitative targeted proteomic approaches are overviewed in this communication. A major advantage of selected reaction monitoring (SRM) and pseudo- SRM lies in the selective and sensitive quantification of selected proteins in large sample sets. ...On the oth …
Novel quantitative targeted proteomic approaches are overviewed in this communication. A major advantage of selected reaction monitoring ( …
Comparing SRM and SWATH Methods for Quantitation of Bovine Muscle Proteomes.
Wu W, Dai RT, Bendixen E. Wu W, et al. J Agric Food Chem. 2019 Feb 6;67(5):1608-1618. doi: 10.1021/acs.jafc.8b05459. Epub 2019 Jan 23. J Agric Food Chem. 2019. PMID: 30624930
The objective of this work was to develop and compare two targeted proteomic methods, namely, selected reaction monitoring (SRM) and sequential window acquisition of all theoretical spectra (SWATH), for the quantification of 11 bovine muscle proteins that may be indicators …
The objective of this work was to develop and compare two targeted proteomic methods, namely, selected reaction monitoring (SRM) and …
Fluorescence-based super-resolution-microscopy strategies for chromatin studies.
Burgers TCQ, Vlijm R. Burgers TCQ, et al. Chromosoma. 2023 Sep;132(3):191-209. doi: 10.1007/s00412-023-00792-9. Epub 2023 Mar 31. Chromosoma. 2023. PMID: 37000292 Free PMC article. Review.
Super-resolution microscopy (SRM) is a prime tool to study chromatin organisation at near biomolecular resolution in the native cellular environment. ...The aim of this review is to introduce the field of diffraction-unlimited SRM to enable an informed selection of …
Super-resolution microscopy (SRM) is a prime tool to study chromatin organisation at near biomolecular resolution in the native cellu …
Super-resolution Microscopy for Biological Imaging.
Yang Z, Samanta S, Yan W, Yu B, Qu J. Yang Z, et al. Adv Exp Med Biol. 2021;3233:23-43. doi: 10.1007/978-981-15-7627-0_2. Adv Exp Med Biol. 2021. PMID: 34053021 Review.
Therefore, this chapter briefly summarizes the basic principles of various SRM methods which have been frequently utilized in biological imaging. The chapter not only gives an overview of the technical advantages and drawbacks about using different SRM techniques fo …
Therefore, this chapter briefly summarizes the basic principles of various SRM methods which have been frequently utilized in biologi …
SRM-based measurements of proprotein convertase subtilisin/kexin type 9 and lipoprotein(a) kinetics in nonhuman primate serum.
Xie F, Emery MG, Gibbs JP, Rock DA, Rock BM. Xie F, et al. Bioanalysis. 2016 Dec;8(24):2551-2563. doi: 10.4155/bio-2016-0146. Bioanalysis. 2016. PMID: 27884075
We aimed to implement the stable isotope-labeled tracers ([(2)H(3)]-leucine) and develop a novel LC-selected reaction monitoring (SRM) mass spectrometry (MS) method to study the kinetics of PCSK9 and Lp(a). RESULTS: A sensitive method using immunoaffinity enrichment couple …
We aimed to implement the stable isotope-labeled tracers ([(2)H(3)]-leucine) and develop a novel LC-selected reaction monitoring (SRM …
Conspiracy spillovers and geoengineering.
Debnath R, Reiner DM, Sovacool BK, Müller-Hansen F, Repke T, Alvarez RM, Fitzgerald SD. Debnath R, et al. iScience. 2023 Feb 28;26(3):106166. doi: 10.1016/j.isci.2023.106166. eCollection 2023 Mar 17. iScience. 2023. PMID: 36994188 Free PMC article.
We also find that positive emotions rise on both the global and country scales following events related to SRM governance, and negative and neutral emotions increase following SRM projects and announcements of experiments. Finally, we also find that online toxicity …
We also find that positive emotions rise on both the global and country scales following events related to SRM governance, and negati …
11,971 results
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