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Cisplatin resistance involves a metabolic reprogramming through ROS and PGC-1α in NSCLC which can be overcome by OXPHOS inhibition.
Cruz-Bermúdez A, Laza-Briviesca R, Vicente-Blanco RJ, García-Grande A, Coronado MJ, Laine-Menéndez S, Palacios-Zambrano S, Moreno-Villa MR, Ruiz-Valdepeñas AM, Lendinez C, Romero A, Franco F, Calvo V, Alfaro C, Acosta PM, Salas C, Garcia JM, Provencio M. Cruz-Bermúdez A, et al. Among authors: ruiz valdepenas am. Free Radic Biol Med. 2019 May 1;135:167-181. doi: 10.1016/j.freeradbiomed.2019.03.009. Epub 2019 Mar 14. Free Radic Biol Med. 2019. PMID: 30880247 Free article.
Concordance between circulating tumor cells and clinical status during follow-up in anaplastic lymphoma kinase (ALK) non-small-cell lung cancer patients.
Provencio M, Pérez-Callejo D, Torrente M, Martin P, Calvo V, Gutiérrez L, Franco F, Coronado MJ, Cruz-Bermúdez JL, Ruiz-Valdepeñas AM, Cruz-Bermúdez A, Sánchez-Beato M, Romero A, García-Grande A. Provencio M, et al. Among authors: ruiz valdepenas am. Oncotarget. 2017 Jul 31;8(35):59408-59416. doi: 10.18632/oncotarget.19722. eCollection 2017 Aug 29. Oncotarget. 2017. PMID: 28938646 Free PMC article.