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The following term was not found in PubMed: MSK-1-mediated
Page 1
DNA damage-triggered activation of cGAS-STING pathway induces apoptosis in human keratinocyte HaCaT cells.
Li C, Liu W, Wang F, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Ikejima T. Li C, et al. Mol Immunol. 2021 Mar;131:180-190. doi: 10.1016/j.molimm.2020.12.037. Epub 2021 Jan 8. Mol Immunol. 2021. PMID: 33423764
NF-kappaB, one of the major downstream components of STING pathway, which usually regulates the classical STING apoptotic pathway, was translocated to nucleus in the HaCaT cells irradiated with UVB. ...Treatment with MRT67307, an inhibitor of TB …
NF-kappaB, one of the major downstream components of STING pathway, which usually regulates the classical STING apoptot …
Conditioned Medium from Human Adipose-Derived Mesenchymal Stem Cell Culture Prevents UVB-Induced Skin Aging in Human Keratinocytes and Dermal Fibroblasts.
Li L, Ngo HTT, Hwang E, Wei X, Liu Y, Liu J, Yi TH. Li L, et al. Int J Mol Sci. 2019 Dec 19;21(1):49. doi: 10.3390/ijms21010049. Int J Mol Sci. 2019. PMID: 31861704 Free PMC article.
Human adipose-derived mesenchymal stem cells-conditioned medium (ADSC-CM) contains cytokines and growth factors that can facilitate the regeneration and repair of various tissues and organs. In the present study, the protective activity of ADSC-CM treatment was investigate …
Human adipose-derived mesenchymal stem cells-conditioned medium (ADSC-CM) contains cytokines and growth factors that can facilitate the rege …
Regulation of MSK1-Mediated NF-kappaB Activation Upon UVB Irradiation.
Carpenter OL, Wu S. Carpenter OL, et al. Photochem Photobiol. 2014 Jan;90(1):155-61. doi: 10.1111/php.12163. Epub 2013 Sep 30. Photochem Photobiol. 2014. PMID: 24033137 Free PMC article.
In this study, we provided evidence that mitogen- and stress-activated protein kinase (MSK1) is responsible for a noncanonical late-phase activation of NF-kappaB upon UVB irradiation. ...Supershift EMSA implicate that the p65, but not p50 …
In this study, we provided evidence that mitogen- and stress-activated protein kinase (MSK1) is responsible for a noncanonical late-p …
Ginsenoside Rk1 Prevents UVB Irradiation-Mediated Oxidative Stress, Inflammatory Response, and Collagen Degradation via the PI3K/AKT/NF-kappaB Pathway In Vitro and In Vivo.
Liu Y, Qu L, Wan S, Li Y, Fan D. Liu Y, et al. J Agric Food Chem. 2022 Dec 21;70(50):15804-15817. doi: 10.1021/acs.jafc.2c06377. Epub 2022 Dec 6. J Agric Food Chem. 2022. PMID: 36472249
Further studies revealed that Rk1 could suppress the PI3K/AKT/NF-kappaB signaling pathways in vitro and in vivo. Molecular docking results indicated that Rk1 might effectively bind to the active pockets of PI3K, AKT, and NF-kappaB. The PI3K a …
Further studies revealed that Rk1 could suppress the PI3K/AKT/NF-kappaB signaling pathways in vitro and in vivo. Molecular doc …
Frog Skin Derived Peptides With Potential Protective Effects on Ultraviolet B-Induced Cutaneous Photodamage.
Liu H, Guo X, Yi T, Zhu Y, Ren X, Guo R, Dai Y, Liang S. Liu H, et al. Front Immunol. 2021 Jun 2;12:613365. doi: 10.3389/fimmu.2021.613365. eCollection 2021. Front Immunol. 2021. PMID: 34149681 Free PMC article.
They may achieve this function by modulating the UV-induced stress signaling pathways such as Mitogen-activated protein kinases (MAPK) and Nuclear Factor Kappa B (NF-kappaB). ...Moreover, this study might expand our knowledge on skin defensive mechanism of tr …
They may achieve this function by modulating the UV-induced stress signaling pathways such as Mitogen-activated protein kinases (MAPK …
NB-UVB irradiation attenuates inflammatory response in psoriasis.
Ye J, Huang H, Luo G, Yin L, Li B, Chen S, Li H, Yang Y, Yang X. Ye J, et al. Dermatol Ther. 2020 Jul;33(4):e13626. doi: 10.1111/dth.13626. Epub 2020 Jul 11. Dermatol Ther. 2020. PMID: 32431049 Free PMC article.
Many triggering factors for psoriasis initiate inflammation via the activation of NF-kappaB. Narrow-band ultraviolet B (NB-UVB) irradiation can be used as a general treatment for psoriasis, although the molecular mechanism has not yet been deter …
Many triggering factors for psoriasis initiate inflammation via the activation of NF-kappaB. Narrow-band ultraviolet B …
The Mechanism of CIRP in Regulation of STAT3 Phosphorylation and Bag-1/S Expression Upon UVB Radiation.
Sun W, Liao Y, Yi Q, Wu S, Tang L, Tong L. Sun W, et al. Photochem Photobiol. 2018 Nov;94(6):1234-1239. doi: 10.1111/php.12981. Epub 2018 Aug 8. Photochem Photobiol. 2018. PMID: 29981150 Free PMC article.
However, the mechanism(s) of CIRP in regulating p-STAT3 activation and Bag-1/S expression have not been fully elucidated. ...These results lead us to propose that CIRP mediates the activation of STAT3-Bag-1/S signaling cascade via activating the JAKs a …
However, the mechanism(s) of CIRP in regulating p-STAT3 activation and Bag-1/S expression have not been fully elucidated. ...T …
miR-1246-overexpressing exosomes suppress UVB-induced photoaging via regulation of TGF-beta/Smad and attenuation of MAPK/AP-1 pathway.
Gao W, Yuan LM, Zhang Y, Huang FZ, Gao F, Li J, Xu F, Wang H, Wang YS. Gao W, et al. Photochem Photobiol Sci. 2023 Jan;22(1):135-146. doi: 10.1007/s43630-022-00304-1. Epub 2022 Sep 16. Photochem Photobiol Sci. 2023. PMID: 36114328
We then determined the anti-photoaging effects of miR-1246-overexpressing exosomes (OE-EX) on both UVB-irradiated human skin fibroblasts (HSFs) and Kunming mice. The results showed that OE-EX could significantly decrease MMP-1 by inhibiting the MAPK/AP-1 signaling p …
We then determined the anti-photoaging effects of miR-1246-overexpressing exosomes (OE-EX) on both UVB-irradiated human skin f …
Rosa davurica inhibits skin photoaging via regulating MAPK/AP-1, NF-kappaB, and Nrf2/HO-1 signaling in UVB-irradiated HaCaTs.
Fang M, Lee HM, Oh S, Zheng S, Bellere AD, Kim M, Choi J, Kim M, Yu D, Yi TH. Fang M, et al. Photochem Photobiol Sci. 2022 Dec;21(12):2217-2230. doi: 10.1007/s43630-022-00290-4. Epub 2022 Sep 14. Photochem Photobiol Sci. 2022. PMID: 36103110
The expression of aging-related markers including mitogen-activated protein kinases/activator protein 1 (MAPK/AP-1), nuclear factor-kappaB (NF-kappaB), and nuclear factor E2-related factor 2/heme oxygenase-1 (Nrf2/HO-1) was evaluated using Weste …
The expression of aging-related markers including mitogen-activated protein kinases/activator protein 1 (MAPK/AP-1), nuclear f …
Interruption of p38MAPK-MSK1-CREB-MITF-M pathway to prevent hyperpigmentation in the skin.
Kim SH, Lee J, Jung J, Kim GH, Yun CY, Jung SH, Hwang BY, Hong JT, Han SB, Jung JK, Kim Y. Kim SH, et al. Int J Biol Sci. 2024 Feb 17;20(5):1688-1704. doi: 10.7150/ijbs.93120. eCollection 2024. Int J Biol Sci. 2024. PMID: 38481807 Free PMC article.
Toll-like receptor 4 (TLR4), a receptor of endotoxin lipopolysaccharide (LPS), is distributed in immune and other cell types including melanocytes where LPS/TLR4 activate transcriptional activity of nuclear factor (NF)-kappaB to express cytokines in in …
Toll-like receptor 4 (TLR4), a receptor of endotoxin lipopolysaccharide (LPS), is distributed in immune and other cell types including melan …
128 results