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Page 1
The expression of RUNDC3B is associated with promoter methylation in lymphoid malignancies.
Burmeister DW, Smith EH, Cristel RT, McKay SD, Shi H, Arthur GL, Davis JW, Taylor KH. Burmeister DW, et al. Hematol Oncol. 2017 Mar;35(1):25-33. doi: 10.1002/hon.2238. Epub 2015 May 25. Hematol Oncol. 2017. PMID: 26011749 Free PMC article.
To elucidate the potential of using DNA methylation in RUNDC3B as a biomarker in lymphoid malignancies, the methylation status of six regions spanning the CpG island in the promoter region of RUNDC3B was determined in cancer cell lines. ...The protein sequence of …
To elucidate the potential of using DNA methylation in RUNDC3B as a biomarker in lymphoid malignancies, the methylation status of six …
ABCB4 variants in adult patients with cholestatic disease are frequent and underdiagnosed.
Avena A, Puggelli S, Morris M, Cerny A, Andrade AR, Pareti E, Bihl F, Cassatella D, Moix I, Merlo E, Rougemont AL, Majno-Hurst P, Vergani D, Mieli-Vergani G, Terziroli Beretta-Piccoli B. Avena A, et al. Dig Liver Dis. 2021 Mar;53(3):329-344. doi: 10.1016/j.dld.2020.12.003. Epub 2020 Dec 31. Dig Liver Dis. 2021. PMID: 33390354
Genotype: Families A and C: c.2211G>A (p.Ala737=) combined with c.959C>T (p.Ser320Phe) in one subject; Family B: c.1130T>C (p.Ile377Thr); Family D: large deletion removing ABCB4 exons 1-4 plus ABCB1, RUNDC3B, SLC25A40, DBF4, ADAM22 exons 1-3; Family E: c.1565T> …
Genotype: Families A and C: c.2211G>A (p.Ala737=) combined with c.959C>T (p.Ser320Phe) in one subject; Family B: c.1130T>C (p.Ile37 …
Comprehensive bioinformatics analysis of acquired progesterone resistance in endometrial cancer cell line.
Li W, Wang S, Qiu C, Liu Z, Zhou Q, Kong D, Ma X, Jiang J. Li W, et al. J Transl Med. 2019 Feb 27;17(1):58. doi: 10.1186/s12967-019-1814-6. J Transl Med. 2019. PMID: 30813939 Free PMC article.
PGR coexpression analysis revealed 7 PGR coexpressed genes (ANO1, SOX17, CGNL1, DACH1, RUNDC3B, SH3YL1 and CRISPLD1) that were also dramatically changed in IshikawaPR cells. ...
PGR coexpression analysis revealed 7 PGR coexpressed genes (ANO1, SOX17, CGNL1, DACH1, RUNDC3B, SH3YL1 and CRISPLD1) that were also d …
Not only P-glycoprotein: Amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins.
Genovese I, Ilari A, Assaraf YG, Fazi F, Colotti G. Genovese I, et al. Drug Resist Updat. 2017 May;32:23-46. doi: 10.1016/j.drup.2017.10.003. Epub 2017 Oct 16. Drug Resist Updat. 2017. PMID: 29145976 Free article. Review.
Thus, the genes contained in this ABCB1 amplicon including ABCB4, SRI, DBF4, TMEM243, and RUNDC3B are overexpressed in many cancers, and especially in MDR tumors, while TP53TG1 and DMTF1 are bona fide tumor suppressors. ...
Thus, the genes contained in this ABCB1 amplicon including ABCB4, SRI, DBF4, TMEM243, and RUNDC3B are overexpressed in many cancers, …
Dual regulation of P-glycoprotein expression by trichostatin A in cancer cell lines.
Balaguer TM, Gómez-Martínez A, García-Morales P, Lacueva J, Calpena R, Reverte LR, Riquelme NL, Martinez-Lacaci I, Ferragut JA, Saceda M. Balaguer TM, et al. BMC Mol Biol. 2012 Jul 30;13:25. doi: 10.1186/1471-2199-13-25. BMC Mol Biol. 2012. PMID: 22846052 Free PMC article.
Finally, the ABCB1 gene is located in a genetic locus with the nested gene RUNDC3B in the complementary DNA strand, raising the possibility that RUNDC3B expression could interfere with ABCB1 alternative promoter regulation. ...These results suggest that iHDACs such …
Finally, the ABCB1 gene is located in a genetic locus with the nested gene RUNDC3B in the complementary DNA strand, raising the possi …
Activation of the ABCB1 Amplicon in Docetaxel- and Cabazitaxel-Resistant Prostate Cancer Cells.
Lombard AP, Lou W, Armstrong CM, D'Abronzo LS, Ning S, Evans CP, Gao AC. Lombard AP, et al. Mol Cancer Ther. 2021 Oct;20(10):2061-2070. doi: 10.1158/1535-7163.MCT-20-0983. Epub 2021 Jul 29. Mol Cancer Ther. 2021. PMID: 34326198 Free PMC article.
This locus, known as the ABCB1 amplicon, has been demonstrated to be amplified in multidrug-resistant tumor cells, but little is known regarding its role in prostate cancer. We show that two ABCB1-amplicon genes other than ABCB1, RUNDC3B and DBF4, promote cellular viabilit …
This locus, known as the ABCB1 amplicon, has been demonstrated to be amplified in multidrug-resistant tumor cells, but little is known regar …
Role of miRNA-99a-5p in Modulating the Function of Hepatocellular Carcinoma Cells: Bioinformatics Analysis and In Vitro Assay.
Zhang JN, Wei F, Zheng BB, Tang L, Chen FY. Zhang JN, et al. Curr Cancer Drug Targets. 2023;23(6):461-470. doi: 10.2174/1568009623666230202155440. Curr Cancer Drug Targets. 2023. PMID: 36733207
At the same time, the ROC analysis found that it showed great potential for prognostic prediction in HCC and we also predicted that RUNDC3B is the most likely target to which it binds. Finally, the experimental results of overexpression and knockdown confirmed that miRNA-9 …
At the same time, the ROC analysis found that it showed great potential for prognostic prediction in HCC and we also predicted that RUNDC …
Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma.
Finalet Ferreiro J, Rouhigharabaei L, Urbankova H, van der Krogt JA, Michaux L, Shetty S, Krenacs L, Tousseyn T, De Paepe P, Uyttebroeck A, Verhoef G, Taghon T, Vandenberghe P, Cools J, Wlodarska I. Finalet Ferreiro J, et al. PLoS One. 2014 Jul 24;9(7):e102977. doi: 10.1371/journal.pone.0102977. eCollection 2014. PLoS One. 2014. PMID: 25057852 Free PMC article.
Gain and amplification of 7q22.11q31.1 are associated with an increased expression of several genes postulated to be implicated in cancer, including RUNDC3B, PPP1R9A and ABCB1, a known multidrug resistance gene. RNA-sequencing did not identify any disease-defining mutation …
Gain and amplification of 7q22.11q31.1 are associated with an increased expression of several genes postulated to be implicated in cancer, i …
Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines.
Januchowski R, Sterzyńska K, Zawierucha P, Ruciński M, Świerczewska M, Partyka M, Bednarek-Rajewska K, Brązert M, Nowicki M, Zabel M, Klejewski A. Januchowski R, et al. Oncotarget. 2017 Jul 25;8(30):49944-49958. doi: 10.18632/oncotarget.18278. Oncotarget. 2017. PMID: 28611294 Free PMC article.
In the CisPt-resistant cell line, we observed downregulated expression of ABCC6, BST2, ERAP2 and MCTP1; in the Pac-resistant cell line, we observe upregulated expression of ABCB1, EPHA7 and RUNDC3B and downregulated expression of LIPG, MCTP1, NSBP1, PCDH9, PTPRK and SEMA3A …
In the CisPt-resistant cell line, we observed downregulated expression of ABCC6, BST2, ERAP2 and MCTP1; in the Pac-resistant cell line, we o …
16 results