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A comparative review of use of sulphate and phosphate salts for colonoscopy preparations and their potential for nephrotoxicity.
Moulin B, Ponchon T. Moulin B, et al. Endosc Int Open. 2018 Oct;6(10):E1206-E1213. doi: 10.1055/a-0581-8723. Epub 2018 Oct 8. Endosc Int Open. 2018. PMID: 30302378 Free PMC article. Review.
This review compares two low-volume high-osmolarity bowel cleansing preparations, oral phosphate salts and oral sulphate salts, with a particular focus on risk of nephrotoxicity. ...Conclusions Oral phosphate salts are no longer re …
This review compares two low-volume high-osmolarity bowel cleansing preparations, oral phosphate salts and oral …
Phosphate salt bowel preparation regimens alter perioperative acid-base and electrolyte balance.
Ezri T, Lerner E, Muggia-Sullam M, Medalion B, Tzivian A, Cherniak A, Szmuk P, Shimonov M. Ezri T, et al. Can J Anaesth. 2006 Feb;53(2):153-8. doi: 10.1007/BF03021820. Can J Anaesth. 2006. PMID: 16434755 Clinical Trial.
BACKGROUND: Hyperphosphatemic acidosis and severe electrolyte disturbances caused by phosphate salts (PO) used for mechanical bowel preparation have been described in occasional case reports prior to bowel resection surgery. ...METHODS: F …
BACKGROUND: Hyperphosphatemic acidosis and severe electrolyte disturbances caused by phosphate salts (PO) used for mechanical …
Highly efficient one-pot labeling of new phosphonium cations with fluorine-18 as potential PET agents for myocardial perfusion imaging.
Zhao Z, Yu Q, Mou T, Liu C, Yang W, Fang W, Peng C, Lu J, Liu Y, Zhang X. Zhao Z, et al. Mol Pharm. 2014 Nov 3;11(11):3823-31. doi: 10.1021/mp500216g. Epub 2014 Jun 5. Mol Pharm. 2014. PMID: 24852080
Lipophilic cations such as phosphonium salts can accumulate in mitochondria of heart in response to the negative inner-transmembrane potentials. Two phosphonium salts [(18)F]FMBTP and [(18)F]mFMBTP were prepared and evaluated as potential myocardial perfusion …
Lipophilic cations such as phosphonium salts can accumulate in mitochondria of heart in response to the negative inner-transmembrane …
Mixed Micelles Loaded with Bile Salt: An Approach to Enhance Intestinal Transport of the BCS Class III Drug Cefotaxime in Rats.
Arafat M, Kirchhoefer C, Mikov M. Arafat M, et al. Eur J Drug Metab Pharmacokinet. 2017 Aug;42(4):635-645. doi: 10.1007/s13318-016-0375-9. Eur J Drug Metab Pharmacokinet. 2017. PMID: 27686853
The main purpose of this study was to investigate the ability of a mixed micelles made of phosphatidylcholine, sodium deoxycholate, and loaded with a cefotaxime-3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate complex to enhance the oral bioavailability of cefotaxime in rats. M …
The main purpose of this study was to investigate the ability of a mixed micelles made of phosphatidylcholine, sodium deoxycholate, and load …
Phytantriol and glyceryl monooleate cubic liquid crystalline phases as sustained-release oral drug delivery systems for poorly water soluble drugs I. Phase behaviour in physiologically-relevant media.
Nguyen TH, Hanley T, Porter CJ, Larson I, Boyd BJ. Nguyen TH, et al. J Pharm Pharmacol. 2010 Jul;62(7):844-55. doi: 10.1211/jpp.62.06.0005. J Pharm Pharmacol. 2010. PMID: 20636872
The phase behaviour of lipid-based liquid crystals formed by phytantriol and glyceryl monooleate, known to form a bicontinuous cubic phase in excess water, was therefore assessed in physiologically-relevant simulated gastrointestinal media. METHODS: Fixed composition phase …
The phase behaviour of lipid-based liquid crystals formed by phytantriol and glyceryl monooleate, known to form a bicontinuous cubic phase i …