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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
2000 1
2001 2
2004 1
2006 1
2008 2
2009 2
2010 2
2011 1
2012 1
2013 1
2018 2
2019 1
2020 1
2021 4
2022 1
2023 1
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22 results

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Tumor suppressor PNRC1 blocks rRNA maturation by recruiting the decapping complex to the nucleolus.
Gaviraghi M, Vivori C, Pareja Sanchez Y, Invernizzi F, Cattaneo A, Santoliquido BM, Frenquelli M, Segalla S, Bachi A, Doglioni C, Pelechano V, Cittaro D, Tonon G. Gaviraghi M, et al. EMBO J. 2018 Dec 3;37(23):e99179. doi: 10.15252/embj.201899179. Epub 2018 Oct 29. EMBO J. 2018. PMID: 30373810 Free PMC article.
Amid the genes belonging to this signature, we have identified PNRC1, a nuclear receptor coactivator. We found that PNRC1 interacts with the cytoplasmic DCP1alpha/DCP2 decapping machinery and hauls it inside the nucleolus. PNRC1-dependent nucleolar translocat …
Amid the genes belonging to this signature, we have identified PNRC1, a nuclear receptor coactivator. We found that PNRC1 inte …
Identification of 3 key genes as novel diagnostic and therapeutic targets for OA and COVID-19.
Zhang Y, Duan Z, Guan Y, Xu T, Fu Y, Li G. Zhang Y, et al. Front Immunol. 2023 May 22;14:1167639. doi: 10.3389/fimmu.2023.1167639. eCollection 2023. Front Immunol. 2023. PMID: 37283761 Free PMC article.
RESULTS: Firstly, WGCNA identified a total of 26 genes common between OA and COVID-19, and functional analysis of the common genes revealed the common pathological processes and molecular changes between OA and COVID-19 are mainly related to immune dysfunction. In addition, we sc …
RESULTS: Firstly, WGCNA identified a total of 26 genes common between OA and COVID-19, and functional analysis of the common genes revealed …
A novel SNP of the PNRC1 gene and its association with reproductive traits in Tsaiya ducks.
Chang MT, Cheng YS, Huang MC. Chang MT, et al. Theriogenology. 2012 Jul 1;78(1):140-6. doi: 10.1016/j.theriogenology.2012.01.029. Epub 2012 Apr 10. Theriogenology. 2012. PMID: 22494678
Proline-rich nuclear receptor coactivator (PNRC)1 is a member of a new family of nuclear receptor coactivators capable of potentiating the transcriptional activity of nuclear receptors. The objective was to investigate the relationship between PNRC1 genotypes of single nuc …
Proline-rich nuclear receptor coactivator (PNRC)1 is a member of a new family of nuclear receptor coactivators capable of potentiating the t …
Decapping enzymes STOP "cancer" ribosomes in their tracks.
Mugridge JS, Gross JD. Mugridge JS, et al. EMBO J. 2018 Dec 3;37(23):e100801. doi: 10.15252/embj.2018100801. Epub 2018 Nov 19. EMBO J. 2018. PMID: 30455174 Free PMC article.
A new study by Gaviraghi et al (2018) shows that mRNA decapping coactivator PNRC1 acts as a tumor suppressor by regulating ribosome biogenesis. ...By slowing rRNA processing, and thus ribosome biogenesis, PNRC1 acts as a gatekeeper that restrains oncogenic potential …
A new study by Gaviraghi et al (2018) shows that mRNA decapping coactivator PNRC1 acts as a tumor suppressor by regulating ribosome b …
Genetic variants as biomarkers for progression and resistance in multiple myeloma.
Montel RA, Gregory M, Chu T, Cottrell J, Bitasktsis C, Chang SL. Montel RA, et al. Cancer Genet. 2021 Apr;252-253:1-5. doi: 10.1016/j.cancergen.2020.12.001. Epub 2020 Dec 6. Cancer Genet. 2021. PMID: 33338886 Free PMC article.
The initial significant protein-coding mutations were found in NRAS, KRAS and TP53 and later reported in FAM46C, DIS3, CCND1, PNRC1, ALOX12B, HLA-A and MAGED1. Here, we report gene network associations of MM using Qiagen's Ingenuity Pathway Analysis (IPA) software and comp …
The initial significant protein-coding mutations were found in NRAS, KRAS and TP53 and later reported in FAM46C, DIS3, CCND1, PNRC1, …
Transcription factor RFX7 governs a tumor suppressor network in response to p53 and stress.
Coronel L, Riege K, Schwab K, Förste S, Häckes D, Semerau L, Bernhart SH, Siebert R, Hoffmann S, Fischer M. Coronel L, et al. Nucleic Acids Res. 2021 Jul 21;49(13):7437-7456. doi: 10.1093/nar/gkab575. Nucleic Acids Res. 2021. PMID: 34197623 Free PMC article.
Integrative analysis of the RFX7 DNA binding landscape and the RFX7-regulated transcriptome in three distinct cell systems reveals that RFX7 directly controls multiple established tumor suppressors, including PDCD4, PIK3IP1, MXD4, and PNRC1, across cell types and is the mi …
Integrative analysis of the RFX7 DNA binding landscape and the RFX7-regulated transcriptome in three distinct cell systems reveals that RFX7 …
Patterns of Crystallin Gene Expression in Differentiation State Specific Regions of the Embryonic Chicken Lens.
Ma Z, Chauss D, Disatham J, Jiao X, Brennan LA, Menko AS, Kantorow M, Hejtmancik JF. Ma Z, et al. Invest Ophthalmol Vis Sci. 2022 Apr 1;63(4):8. doi: 10.1167/iovs.63.4.8. Invest Ophthalmol Vis Sci. 2022. PMID: 35412582 Free PMC article.
Highly expressed crystallin genes fell into three coordinately expressed groups with R2 0.93: CRYAA, CRYBB2, CRYAB, and CRYBA2; CRYBB1, CRYBA4, CRYGN, ASL1, and ASL; and CRYBB3 and CRYBA1. The highly expressed transcription factors YBX1, YBX3, PNRC1, and BASP1 were coordin …
Highly expressed crystallin genes fell into three coordinately expressed groups with R2 0.93: CRYAA, CRYBB2, CRYAB, and CRYBA2; CRYBB1, CRYB …
Comprehensive analysis of differentially expressed microRNAs and mRNAs in MDBK cells expressing bovine papillomavirus E5 oncogene.
Pang F, Chen Z, Wang C, Zhang M, Zhang Z, Yang X, Zheng Y, Liu A, Cheng Y, Chen J, Li B, Du L, Wang F. Pang F, et al. PeerJ. 2019 Nov 22;7:e8098. doi: 10.7717/peerj.8098. eCollection 2019. PeerJ. 2019. PMID: 31772843 Free PMC article.
Of these, downregulation of six miRNAs, bta-miR-34c, bta-miR-122, bta-miR-195, bta-miR-449b, bta-miR-2425-5p, and bta-miR-2428-3p were confirmed; In addition, upregulation of 16 genes, ACSS2, DDIT4, INHBE, INSIG1, PNRC1, PSAT1, PSPH, PYCR1, SC4MOL, SLC34A2, SCD, SPARC, IDI …
Of these, downregulation of six miRNAs, bta-miR-34c, bta-miR-122, bta-miR-195, bta-miR-449b, bta-miR-2425-5p, and bta-miR-2428-3p were confi …
The Identification of a Tumor Infiltration CD8+ T-Cell Gene Signature That Can Potentially Improve the Prognosis and Prediction of Immunization Responses in Papillary Renal Cell Carcinoma.
Wang J, Huang M, Huang P, Zhao J, Tan J, Huang F, Ma R, Xiao Y, Deng G, Wei L, Wei Q, Wang Z, He S, Shen J, Sooranna S, Meng L, Song J. Wang J, et al. Front Oncol. 2021 Nov 10;11:757641. doi: 10.3389/fonc.2021.757641. eCollection 2021. Front Oncol. 2021. PMID: 34858833 Free PMC article.
RESULTS: Six hundred twenty-one cell death-inhibiting RNA genes were screened using single-cell RNA sequencing. A gene signature consisting of seven genes (LYAR, YBX1, PNRC1, TCF25, MYL12B, MINOS1, and LINC01420) was then identified, and this collective was considered to b …
RESULTS: Six hundred twenty-one cell death-inhibiting RNA genes were screened using single-cell RNA sequencing. A gene signature consisting …
22 results