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Year Number of Results
1999 1
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2023 4
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33 results

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[Functional Hypermethylation of ALDH1L1, PLCL2, and PPP2R3A in Colon Cancer].
Dmitriev AA, Beniaminov AD, Melnikova NV, Pushkova EN, Gerashchenko GV, Kudryavtseva AV, Kashuba VI. Dmitriev AA, et al. Mol Biol (Mosk). 2020 Mar-Apr;54(2):204-211. doi: 10.1134/S002689842001005X. Mol Biol (Mosk). 2020. PMID: 32392189 Free article. Russian.
Expression and promoter methylation of these genes were analyzed using the data for paired colon samples from The Cancer Genome Atlas project. Three genes - ALDH1L1, PLCL2, and PPP2R3A - revealed a more than two-fold average decrease in expression and a negative correlatio …
Expression and promoter methylation of these genes were analyzed using the data for paired colon samples from The Cancer Genome Atlas projec …
Fine-Mapping of the PLCL2 Gene Identifies Candidate Variants Associated With Ischaemic Stroke Risk in Metabolic Syndrome Patients.
Huang X, Ye Q, Zhang Y, Chen Y, Li J, Sun J, Ye Z. Huang X, et al. Front Neurol. 2022 Jan 20;12:743169. doi: 10.3389/fneur.2021.743169. eCollection 2021. Front Neurol. 2022. PMID: 35126281 Free PMC article.
A genome-wide association study (GWAS) reported PLCL2 on chromosome 3p24. 3 (rs4618210:A>G) as a novel susceptibility locus for myocardial infarction in the Japanese population. ...A fine-mapping strategy was adopted to identify tagged single nucleotide polymorphisms (S …
A genome-wide association study (GWAS) reported PLCL2 on chromosome 3p24. 3 (rs4618210:A>G) as a novel susceptibility locus for my …
Two Novel SNPs in the PLCL2 Gene Associated with Large Artery Atherosclerotic Stroke Identified by Fine-Mapping.
Huang X, Zhu Z, Chen Y, Li J, Xia N, Chen S, Geng W, Ye Z. Huang X, et al. J Mol Neurosci. 2020 Apr;70(4):496-503. doi: 10.1007/s12031-019-01436-3. Epub 2020 Jan 22. J Mol Neurosci. 2020. PMID: 31970634
A genome-wide association study (GWAS) reported that the single nucleotide polymorphism (SNP) rs4618210 in the PLCL2 gene is related to myocardial infarction (MI) in the Japanese population, but no study has examined the correlation of PLCL2 with ischemic stroke (IS …
A genome-wide association study (GWAS) reported that the single nucleotide polymorphism (SNP) rs4618210 in the PLCL2 gene is related …
Progesterone receptor isoform B regulates the Oxtr-Plcl2-Trpc3 pathway to suppress uterine contractility.
Peavey MC, Wu SP, Li R, Liu J, Emery OM, Wang T, Zhou L, Wetendorf M, Yallampalli C, Gibbons WE, Lydon JP, DeMayo FJ. Peavey MC, et al. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2011643118. doi: 10.1073/pnas.2011643118. Proc Natl Acad Sci U S A. 2021. PMID: 33707208 Free PMC article.
Elevated PGR-B abundance reduces Oxtr and Trpc3 and increases Plcl2 expression, which manifests a genetic profile of compromised oxytocin signaling. Functionally, both endogenous PLCL2 and its paralog PLCL1 can attenuate uterine muscle cell contraction in a CRISPRa- …
Elevated PGR-B abundance reduces Oxtr and Trpc3 and increases Plcl2 expression, which manifests a genetic profile of compromised oxyt …
Association of rs4618210A>G variant in PLCL2 gene with myocardial infarction: A case-control study in Iran.
Ramezanpour N, Nasiri M, Akbarpour OR. Ramezanpour N, et al. J Cardiovasc Thorac Res. 2020;12(4):303-306. doi: 10.34172/jcvtr.2020.49. Epub 2020 Nov 28. J Cardiovasc Thorac Res. 2020. PMID: 33510879 Free PMC article.
The present study was undertaken to investigate whether rs4618210A>G polymorphism in PLCL2 gene contribute to MI etiology. Methods: A hospital-based case-control study with 600 subjects, including 300 MI patients and 300controls, was conducted. Genotyping of PLCL2 …
The present study was undertaken to investigate whether rs4618210A>G polymorphism in PLCL2 gene contribute to MI etiology. Methods …
Genome-wide identification of RNA modification-related single nucleotide polymorphisms associated with rheumatoid arthritis.
Wang M, Wu J, Lei S, Mo X. Wang M, et al. BMC Genomics. 2023 Mar 27;24(1):153. doi: 10.1186/s12864-023-09227-2. BMC Genomics. 2023. PMID: 36973646 Free PMC article.
RNAm-SNPs in important RA susceptibility genes, such as PADI2, SPRED2, PLCL2, HLA-A, HLA-B, HLA-DRB1, HLA-DPB1, TRAF1 and TXNDC11, were identified. ...
RNAm-SNPs in important RA susceptibility genes, such as PADI2, SPRED2, PLCL2, HLA-A, HLA-B, HLA-DRB1, HLA-DPB1, TRAF1 and TXNDC11, we …
Identification of NF-kappaB and PLCL2 as new susceptibility genes and highlights on a potential role of IRF8 through interferon signature modulation in systemic sclerosis.
Arismendi M, Giraud M, Ruzehaji N, Dieudé P, Koumakis E, Ruiz B, Airo P, Cusi D, Matucci-Cerinic M, Salvi E, Cuomo G, Hachulla E, Diot E, Caramaschi P, Riccieri V, Avouac J, Kayser C, Allanore Y. Arismendi M, et al. Arthritis Res Ther. 2015 Mar 21;17(1):71. doi: 10.1186/s13075-015-0572-y. Arthritis Res Ther. 2015. PMID: 25880423 Free PMC article.
METHODS: Sixteen PBC susceptibility SNPs were genotyped in a total of 1,616 patients with SSc and 3,621 healthy controls from two European populations (France and Italy). RESULTS: We observed an association between PLCL2 rs1372072 (odds ratio (OR) = 1.22, 95% confidence in …
METHODS: Sixteen PBC susceptibility SNPs were genotyped in a total of 1,616 patients with SSc and 3,621 healthy controls from two European p …
A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
Hirokawa M, Morita H, Tajima T, Takahashi A, Ashikawa K, Miya F, Shigemizu D, Ozaki K, Sakata Y, Nakatani D, Suna S, Imai Y, Tanaka T, Tsunoda T, Matsuda K, Kadowaki T, Nakamura Y, Nagai R, Komuro I, Kubo M. Hirokawa M, et al. Eur J Hum Genet. 2015 Mar;23(3):374-80. doi: 10.1038/ejhg.2014.110. Epub 2014 Jun 11. Eur J Hum Genet. 2015. PMID: 24916648 Free PMC article.
We performed replication studies using a total of 11,412 cases and 28,397 controls in the Japanese population. Our study identified two novel susceptibility loci for MI: PLCL2 on chromosome 3p24.3 (rs4618210:A>G, P = 2.60 10(-9), odds ratio (OR) = 0.91) and AP3D1-DOT1L- …
We performed replication studies using a total of 11,412 cases and 28,397 controls in the Japanese population. Our study identified two nove …
A novel fatty-acid metabolism-based classification for triple negative breast cancer.
Yang X, Tang W, He Y, An H, Wang J. Yang X, et al. Aging (Albany NY). 2023 Feb 25;15(4):1177-1198. doi: 10.18632/aging.204552. Epub 2023 Feb 25. Aging (Albany NY). 2023. PMID: 36880837 Free PMC article.
Further analyses in our cohort found that the differential expression of CXCL13, FBP1 and PLCL2 were significantly associated with clinical outcomes of TNBC samples. ...
Further analyses in our cohort found that the differential expression of CXCL13, FBP1 and PLCL2 were significantly associated with cl …
Variants in 3p24.3 predicts the risk of early neurological deterioration in large artery atherosclerotic stroke.
Huang X, Ye Q, Zhu Z, Chen Y, Xia N, Chen R, Geng W, Ye Z. Huang X, et al. Brain Res. 2024 Mar 16;1833:148867. doi: 10.1016/j.brainres.2024.148867. Online ahead of print. Brain Res. 2024. PMID: 38499234
The objective of this research is to examine the efficacy that PLCL2 may have on the risk of END in large artery atherosclerotic (LAA) stroke. ...The SNP-SNP interactions of PLCL2 for END was assessed by generalized multifactor dimensionality reduction (GMDR). ...
The objective of this research is to examine the efficacy that PLCL2 may have on the risk of END in large artery atherosclerotic (LAA …
33 results