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294 results

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Page 1
Novel Diagnostic Biomarkers Related to Oxidative Stress and Macrophage Ferroptosis in Atherosclerosis.
Li M, Xin S, Gu R, Zheng L, Hu J, Zhang R, Dong H. Li M, et al. Oxid Med Cell Longev. 2022 Aug 5;2022:8917947. doi: 10.1155/2022/8917947. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 36035208 Free PMC article.
High ALOX5 and NCF2 expression levels in plaque tissues were confirmed by immunohistochemistry (IHC) and western blotting. ...ALOX5 and NCF2 may be involved in the formation of the necrotic core in AS by regulating macrophage ferroptosis....
High ALOX5 and NCF2 expression levels in plaque tissues were confirmed by immunohistochemistry (IHC) and western blotting. ...ALOX5 a …
Altered NCF2, NOX2 mRNA Expression Levels in Peripheral Blood Mononuclear Cells of Pulmonary Tuberculosis Patients.
Li HM, Huang Q, Tang F, Zhang TP. Li HM, et al. Int J Gen Med. 2021 Dec 1;14:9203-9209. doi: 10.2147/IJGM.S339194. eCollection 2021. Int J Gen Med. 2021. PMID: 34880659 Free PMC article.
Quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR) was used to measure the NCF2, NOX2 mRNA levels, and receiver operating characteristic (ROC) curve analysis was performed to assess the diagnostic value of NCF2, NOX2 in PTB patients. .. …
Quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR) was used to measure the NCF2, NOX2 mRNA levels, and …
Exploring the Pathogenesis of Psoriasis Complicated With Atherosclerosis via Microarray Data Analysis.
Su W, Zhao Y, Wei Y, Zhang X, Ji J, Yang S. Su W, et al. Front Immunol. 2021 May 27;12:667690. doi: 10.3389/fimmu.2021.667690. eCollection 2021. Front Immunol. 2021. PMID: 34122426 Free PMC article.
Finally, 16 important hub genes were identified using cytoHubba, including LYN, CSF2RB, IL1RN, RAC2, CCL5, IRF8, C1QB, MMP9, PLEK, PTPRC, FYB, BCL2A1, LCP2, CD53, NCF2 and TLR2. CONCLUSIONS: Our study reveals the common pathogenesis of psoriasis and atherosclerosis. ...
Finally, 16 important hub genes were identified using cytoHubba, including LYN, CSF2RB, IL1RN, RAC2, CCL5, IRF8, C1QB, MMP9, PLEK, PTPRC, FY …
Novel NCF2 Mutation Causing Chronic Granulomatous Disease.
Roth IL, Salamon P, Freund T, Gadot YB, Baron S, Hershkovitz T, Shefler I, Hanna S, Confino-Cohen R, Bentur L, Hagin D. Roth IL, et al. J Clin Immunol. 2020 Oct;40(7):977-986. doi: 10.1007/s10875-020-00820-8. Epub 2020 Jul 14. J Clin Immunol. 2020. PMID: 32666379
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder caused by defects in the NADPH oxidase complex. Mutations in NCF2 encoding the cytosolic factor p67(phox) result in autosomal recessive CGD. ...Clinically, the homozygous patient presented with …
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder caused by defects in the NADPH oxidase complex. Mutations in …
Role of NCF2 as a potential prognostic factor and immune infiltration indicator in hepatocellular carcinoma.
Huang N, Zhang J, Kuang S, Li Z, Zhao H, Wu J, Liu M, Wang L. Huang N, et al. Cancer Med. 2023 Apr;12(7):8991-9004. doi: 10.1002/cam4.5597. Epub 2023 Jan 20. Cancer Med. 2023. PMID: 36680322 Free PMC article.
The survival analysis based on NCF2 expression assessed by immunohistochemistry also confirmed that NCF2-positive group had a shorter relapse free survival (RFS) and overall survival (OS) than NCF2-negative group. ...Besides, the expression level of NCF2
The survival analysis based on NCF2 expression assessed by immunohistochemistry also confirmed that NCF2-positive group had a …
Chronic Granulomatous Disease.
Leiding JW, Holland SM. Leiding JW, et al. 2012 Aug 9 [updated 2022 Apr 21]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2012 Aug 9 [updated 2022 Apr 21]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 22876374 Free Books & Documents. Review.
DIAGNOSIS/TESTING: The diagnosis of CGD is established in a proband with suggestive findings by identification of pathogenic variant(s) in one of six genes that encode or permit assembly of the subunits of phagocyte NADPH oxidase: biallelic pathogenic variants in CYBA, CYBC1, NCF …
DIAGNOSIS/TESTING: The diagnosis of CGD is established in a proband with suggestive findings by identification of pathogenic variant(s) in o …
A novel variant in the neutrophil cytosolic factor 2 (NCF2) gene results in severe disseminated BCG infectious disease: A clinical report and literature review.
AlKhater SA, Deswarte C, Casanova JL, Bustamante J. AlKhater SA, et al. Mol Genet Genomic Med. 2020 Jun;8(6):e1237. doi: 10.1002/mgg3.1237. Epub 2020 Apr 12. Mol Genet Genomic Med. 2020. PMID: 32281309 Free PMC article. Review.
The rarest form of the disease is considered to be caused by NCF2 gene bi-allelic variant. Here, we report the clinical and molecular characterization of a patient presenting with early-onset severe disease due to bi-allelic NCF2 variant. ...Whole-exome sequencing i …
The rarest form of the disease is considered to be caused by NCF2 gene bi-allelic variant. Here, we report the clinical and molecular …
Key Genes Associated With Non-Alcoholic Fatty Liver Disease and Polycystic Ovary Syndrome.
Chen Y, Ma L, Ge Z, Pan Y, Xie L. Chen Y, et al. Front Mol Biosci. 2022 May 25;9:888194. doi: 10.3389/fmolb.2022.888194. eCollection 2022. Front Mol Biosci. 2022. PMID: 35693550 Free PMC article.
GO and KEGG enrichment analysis indicated that DEGs are mostly enriched in immunity and inflammation related pathways. In addition, nine hub genes, including TREM1, S100A9, FPR1, NCF2, FCER1G, CCR1, S100A12, MMP9, and IL1RN were selected from the PPI network by using the c …
GO and KEGG enrichment analysis indicated that DEGs are mostly enriched in immunity and inflammation related pathways. In addition, nine hub …
Identification of NCF2/p67phox as a novel p53 target gene.
Italiano D, Lena AM, Melino G, Candi E. Italiano D, et al. Cell Cycle. 2012 Dec 15;11(24):4589-96. doi: 10.4161/cc.22853. Epub 2012 Nov 27. Cell Cycle. 2012. PMID: 23187810 Free PMC article.
Analysis of microarrays performed in p53-, TAp63alpha- and deltaNp63alpha-inducible SaOs-2 cell lines allowed the identification of NCF2 mRNA upregulation in response to p53 induction. NCF2 gene encodes for p67phox, the cytosolic subunit of the NADPH oxidase enzyme …
Analysis of microarrays performed in p53-, TAp63alpha- and deltaNp63alpha-inducible SaOs-2 cell lines allowed the identification of NCF2
294 results