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Results: 1 to 20 of 68

1.

Mitochondria, Energetics, Epigenetics, and Cellular Responses to Stress.

Shaughnessy DT, McAllister K, Worth L, Haugen AC, Meyer JN, Domann FE, Van Houten B, Mostoslavsky R, Bultman SJ, Baccarelli AA, Begley TJ, Sobol R, Hirschey MD, Ideker T, Santos JH, Copeland WC, Tice RR, Balshaw DM, Tyson FL.

Environ Health Perspect. 2014 Aug 15. [Epub ahead of print] Review.

PMID:
25127496
[PubMed - as supplied by publisher]
Free Article
2.

Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism.

Masri S, Rigor P, Cervantes M, Ceglia N, Sebastian C, Xiao C, Roqueta-Rivera M, Deng C, Osborne TF, Mostoslavsky R, Baldi P, Sassone-Corsi P.

Cell. 2014 Jul 31;158(3):659-72. doi: 10.1016/j.cell.2014.06.050.

PMID:
25083875
[PubMed - in process]
3.

Sirtuins, metabolism, and DNA repair.

Choi JE, Mostoslavsky R.

Curr Opin Genet Dev. 2014 Jul 5;26C:24-32. doi: 10.1016/j.gde.2014.05.005. [Epub ahead of print] Review.

PMID:
25005742
[PubMed - as supplied by publisher]
4.

Sirtuin to the rescue: SIRT2 extends life span of BubR1 mice.

Cosentino C, Mostoslavsky R.

EMBO J. 2014 Jul 1;33(13):1417-9. doi: 10.15252/embj.201488983. Epub 2014 Jun 11. No abstract available.

PMID:
24920578
[PubMed - indexed for MEDLINE]
5.

SIRT6 is required for normal retinal function.

Silberman DM, Ross K, Sande PH, Kubota S, Ramaswamy S, Apte RS, Mostoslavsky R.

PLoS One. 2014 Jun 4;9(6):e98831. doi: 10.1371/journal.pone.0098831. eCollection 2014.

PMID:
24896097
[PubMed - in process]
Free PMC Article
6.

Chromatin and beyond: the multitasking roles for SIRT6.

Kugel S, Mostoslavsky R.

Trends Biochem Sci. 2014 Feb;39(2):72-81. doi: 10.1016/j.tibs.2013.12.002. Epub 2014 Jan 14. Review.

PMID:
24438746
[PubMed - indexed for MEDLINE]
7.

SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease.

Shin J, He M, Liu Y, Paredes S, Villanova L, Brown K, Qiu X, Nabavi N, Mohrin M, Wojnoonski K, Li P, Cheng HL, Murphy AJ, Valenzuela DM, Luo H, Kapahi P, Krauss R, Mostoslavsky R, Yancopoulos GD, Alt FW, Chua KF, Chen D.

Cell Rep. 2013 Nov 14;5(3):654-65. doi: 10.1016/j.celrep.2013.10.007. Epub 2013 Nov 7. Erratum in: Cell Rep. 2013 Dec 12;5(5):1479.

PMID:
24210820
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The histone deacetylase SIRT6: at the crossroads between epigenetics, metabolism and disease.

Etchegaray JP, Zhong L, Mostoslavsky R.

Curr Top Med Chem. 2013;13(23):2991-3000. Review.

PMID:
24171769
[PubMed - indexed for MEDLINE]
9.

Assaying chromatin sirtuins.

Zhong L, Martinez-Pastor B, Silberman DM, Sebastian C, Mostoslavsky R.

Methods Mol Biol. 2013;1077:149-63. doi: 10.1007/978-1-62703-637-5_10.

PMID:
24014405
[PubMed - indexed for MEDLINE]
10.

SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling.

Toiber D, Erdel F, Bouazoune K, Silberman DM, Zhong L, Mulligan P, Sebastian C, Cosentino C, Martinez-Pastor B, Giacosa S, D'Urso A, Näär AM, Kingston R, Rippe K, Mostoslavsky R.

Mol Cell. 2013 Aug 22;51(4):454-68. doi: 10.1016/j.molcel.2013.06.018. Epub 2013 Aug 1.

PMID:
23911928
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A tale of metabolites: the cross-talk between chromatin and energy metabolism.

Martinez-Pastor B, Cosentino C, Mostoslavsky R.

Cancer Discov. 2013 May;3(5):497-501. doi: 10.1158/2159-8290.CD-13-0059.

PMID:
23658298
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine.

Jiang H, Khan S, Wang Y, Charron G, He B, Sebastian C, Du J, Kim R, Ge E, Mostoslavsky R, Hang HC, Hao Q, Lin H.

Nature. 2013 Apr 4;496(7443):110-3. doi: 10.1038/nature12038.

PMID:
23552949
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

SIRT1 activators: the evidence STACks up.

Kugel S, Mostoslavsky R.

Aging (Albany NY). 2013 Mar;5(3):142-3. No abstract available.

PMID:
23474671
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Metabolism, longevity and epigenetics.

Cosentino C, Mostoslavsky R.

Cell Mol Life Sci. 2013 May;70(9):1525-41. doi: 10.1007/s00018-013-1295-3. Epub 2013 Mar 7. Review.

PMID:
23467663
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism.

Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, Cosentino C, Greenson JK, MacDonald AI, McGlynn L, Maxwell F, Edwards J, Giacosa S, Guccione E, Weissleder R, Bernstein BE, Regev A, Shiels PG, Lombard DB, Mostoslavsky R.

Cell. 2012 Dec 7;151(6):1185-99. doi: 10.1016/j.cell.2012.10.047.

PMID:
23217706
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis.

Dominy JE Jr, Lee Y, Jedrychowski MP, Chim H, Jurczak MJ, Camporez JP, Ruan HB, Feldman J, Pierce K, Mostoslavsky R, Denu JM, Clish CB, Yang X, Shulman GI, Gygi SP, Puigserver P.

Mol Cell. 2012 Dec 28;48(6):900-13. doi: 10.1016/j.molcel.2012.09.030. Epub 2012 Nov 8.

PMID:
23142079
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

From sirtuin biology to human diseases: an update.

Sebastián C, Satterstrom FK, Haigis MC, Mostoslavsky R.

J Biol Chem. 2012 Dec 14;287(51):42444-52. doi: 10.1074/jbc.R112.402768. Epub 2012 Oct 18. Review.

PMID:
23086954
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses.

Bauer I, Grozio A, Lasigliè D, Basile G, Sturla L, Magnone M, Sociali G, Soncini D, Caffa I, Poggi A, Zoppoli G, Cea M, Feldmann G, Mostoslavsky R, Ballestrero A, Patrone F, Bruzzone S, Nencioni A.

J Biol Chem. 2012 Nov 30;287(49):40924-37. doi: 10.1074/jbc.M112.405837. Epub 2012 Oct 18.

PMID:
23086953
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun.

Sundaresan NR, Vasudevan P, Zhong L, Kim G, Samant S, Parekh V, Pillai VB, Ravindra PV, Gupta M, Jeevanandam V, Cunningham JM, Deng CX, Lombard DB, Mostoslavsky R, Gupta MP.

Nat Med. 2012 Nov;18(11):1643-50. doi: 10.1038/nm.2961. Epub 2012 Oct 21.

PMID:
23086477
[PubMed - indexed for MEDLINE]
20.

Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction.

Montecucco F, Bauer I, Braunersreuther V, Bruzzone S, Akhmedov A, Lüscher TF, Speer T, Poggi A, Mannino E, Pelli G, Galan K, Bertolotto M, Lenglet S, Garuti A, Montessuit C, Lerch R, Pellieux C, Vuilleumier N, Dallegri F, Mage J, Sebastian C, Mostoslavsky R, Gayet-Ageron A, Patrone F, Mach F, Nencioni A.

Antioxid Redox Signal. 2013 Feb 20;18(6):630-41. doi: 10.1089/ars.2011.4487. Epub 2012 May 14.

PMID:
22452634
[PubMed - indexed for MEDLINE]
Free PMC Article

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