MicroRNAs: a new class of regulatory genes affecting metabolism.
Cell Metab. 2006.
PMID: 16814728
Review.
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MicroRNAs: a new class of regulatory genes affecting metabolism.
Cell Metab. 2006 Jul;4(1):9-12. doi: 10.1016/j.cmet.2006.05.009.
Cell Metab. 2006.
PMID: 16814728
Free article.
Review.
Although hundreds of miRNAs have been identified, much less is known about their biological function. Several studies have provided evidence that miRNAs affect pathways that are fundamental for metabolic control in higher organisms such as adipocyte and skeletal mus …
Although hundreds of miRNAs have been identified, much less is known about their biological function. Several studies have provided evidence …
MicroRNA regulation of phenotypic transformations in vascular smooth muscle: relevance to vascular remodeling.
Cell Mol Life Sci. 2023 May 10;80(6):144. doi: 10.1007/s00018-023-04793-w.
Cell Mol Life Sci. 2023.
PMID: 37165163
Review.
Alterations in the vascular smooth muscle cells (VSMC) phenotype play a critical role in the pathogenesis of several cardiovascular diseases, including hypertension, atherosclerosis, and restenosis after angioplasty. MicroRNAs (miRNAs) are a class of endogenous nonc …
Alterations in the vascular smooth muscle cells (VSMC) phenotype play a critical role in the pathogenesis of several cardiovascular diseases …
Emerging role of miRNA in attention deficit hyperactivity disorder: a systematic review.
Atten Defic Hyperact Disord. 2018 Mar;10(1):49-63. doi: 10.1007/s12402-017-0232-y. Epub 2017 May 10.
Atten Defic Hyperact Disord. 2018.
PMID: 28493018
Review.
Nevertheless, evidence supports a high genetic contribution that interacts with environmental factors, also known to modulate epigenetic processes. These epigenetic modulators are a class of non-coding RNAs, microRNAs (miRNAs), known as post-transcriptional regulato …
Nevertheless, evidence supports a high genetic contribution that interacts with environmental factors, also known to modulate epigenetic pro …
Aberrant regulation and function of microRNAs in cancer.
Curr Biol. 2014 Aug 18;24(16):R762-76. doi: 10.1016/j.cub.2014.06.043.
Curr Biol. 2014.
PMID: 25137592
Free PMC article.
Review.
Much of this work has concentrated on post-translational modifications and abnormalities at the DNA level, including point mutations, amplifications/deletions, and chromosomal translocations, and how these aberrant events affect the expression and function of protein-codin …
Much of this work has concentrated on post-translational modifications and abnormalities at the DNA level, including point mutations, amplif …
MicroRNA: The Potential Regulator of Endometrial Carcinogenesis.
Microrna. 2015;4(1):18-25. doi: 10.2174/2211536604666150710094418.
Microrna. 2015.
PMID: 26088599
Review.
This class of small posttranscriptional regulatory RNAs originates from the random formation of hairpin precursors in "non-coding" DNA regions; their main function is the control of gene expression status. ...The scientific significance of this new class …
This class of small posttranscriptional regulatory RNAs originates from the random formation of hairpin precursors in "non-cod …
[MicroRNA and metabolism regulation].
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2013 Mar;38(3):318-22. doi: 10.3969/j.issn.1672-7347.2013.03.017.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2013.
PMID: 23545829
Review.
Chinese.
MicroRNAs have been identified as a new class of regulatory molecules that affect many biological functions by interferring the target gene expressions. ...For lipid matebolism, microRNAs can regulate the target genes related to li …
MicroRNAs have been identified as a new class of regulatory molecules that affect many biological functio …
MicroRNA binding site variation is enriched in psychiatric disorders.
Hum Mutat. 2022 Dec;43(12):2153-2169. doi: 10.1002/humu.24481. Epub 2022 Oct 23.
Hum Mutat. 2022.
PMID: 36217923
Free PMC article.
Most associated loci impact noncoding regions of the genome, suggesting that the majority of disease heritability originates from the disruption of regulatory sequences. While most research has focused on variants that modify regulatory DNA elements, those affect …
Most associated loci impact noncoding regions of the genome, suggesting that the majority of disease heritability originates from the disrup …
Plant miR167e-5p promotes 3T3-L1 adipocyte adipogenesis by targeting β-catenin.
In Vitro Cell Dev Biol Anim. 2022 Jun;58(6):471-479. doi: 10.1007/s11626-022-00702-w. Epub 2022 Jul 12.
In Vitro Cell Dev Biol Anim. 2022.
PMID: 35829897
Free PMC article.
Adipogenesis is important in the development of fat deposition. Evidence showed that plant microRNAs (miRNAs) could be absorbed by the digestive tract and exert regulatory effects on animals' physiological processes. ...This research demonstrates that plant miR167e- …
Adipogenesis is important in the development of fat deposition. Evidence showed that plant microRNAs (miRNAs) could be absorbed by th …
HSF-1 is a regulator of miRNA expression in Caenorhabditis elegans.
PLoS One. 2017 Aug 24;12(8):e0183445. doi: 10.1371/journal.pone.0183445. eCollection 2017.
PLoS One. 2017.
PMID: 28837599
Free PMC article.
However, the indirect role of HSF-1 in coordinating stress-dependent and -independent processes through post-transcriptional regulation is largely unknown. MicroRNAs (miRNAs) have emerged as a class of post-transcriptional regulators that control gene expression thr …
However, the indirect role of HSF-1 in coordinating stress-dependent and -independent processes through post-transcriptional regulation is l …
A Novel MicroRNA and the Target Gene TAB2 Can Regulate the Process of Sucking Blood in and the Spawn Rate of Hyalomma asiaticum (Acari: Ixodidae) Ticks.
Front Immunol. 2022 Jul 5;13:930532. doi: 10.3389/fimmu.2022.930532. eCollection 2022.
Front Immunol. 2022.
PMID: 35865515
Free PMC article.
Ticks are blood-sucking parasites that are harmful to humans and animals. MicroRNAs are a class of conserved small noncoding RNAs that play regulatory roles in the expression of many genes at the posttranscriptional level. ...The overexpression of nov- …
Ticks are blood-sucking parasites that are harmful to humans and animals. MicroRNAs are a class of conserved small noncoding R …
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