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Year Number of Results
2009 1
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2011 2
2012 7
2013 1
2014 4
2015 1
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2018 2
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2022 5
2023 6
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36 results

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Page 1
MARVELD3 inhibits the epithelial-mesenchymal transition and cell migration by suppressing the Wnt/beta-catenin signaling pathway in non-small cell lung cancer cells.
Li S, Qi S, Li Y, Zhang C, Sun L, Liu C, Wang H. Li S, et al. Thorac Cancer. 2023 Apr;14(12):1045-1058. doi: 10.1111/1759-7714.14844. Epub 2023 Mar 15. Thorac Cancer. 2023. PMID: 36924014 Free PMC article.
There is limited information available about the mechanism of MARVELD3 in NSCLC. In this trial, the inhibition effect of MARVELD3 on human NSCLC cells will be discussed. ...NSCLC cells with MARVELD3-knockdown and overexpressed were established to analyze the …
There is limited information available about the mechanism of MARVELD3 in NSCLC. In this trial, the inhibition effect of MARVELD3
Claudins and other tight junction proteins.
Günzel D, Fromm M. Günzel D, et al. Compr Physiol. 2012 Jul;2(3):1819-52. doi: 10.1002/cphy.c110045. Compr Physiol. 2012. PMID: 23723025 Review.
Two TJ protein families can be distinguished, claudins, comprising 27 members in mammals, and TJ-associated MARVEL proteins (TAMP), comprising occludin, tricellulin, and MarvelD3. They are linked to a multitude of TJ-associated regulatory and scaffolding proteins. ...
Two TJ protein families can be distinguished, claudins, comprising 27 members in mammals, and TJ-associated MARVEL proteins (TAMP), comprisi …
MarvelD3 Is Upregulated in Ulcerative Colitis and Has Attenuating Effects during Colitis Indirectly Stabilizing the Intestinal Barrier.
Weiß F, Czichos C, Knobe L, Voges L, Bojarski C, Michel G, Fromm M, Krug SM. Weiß F, et al. Cells. 2022 May 4;11(9):1541. doi: 10.3390/cells11091541. Cells. 2022. PMID: 35563847 Free PMC article.
The functional role of the tight junction-associated MARVEL protein MARVELD3 (MD3) in IBD is yet unknown. (i) In colon biopsies from IBD patients we analyzed MD3 expression and (ii) in human colon HT-29/B6 cells we studied the signaling pathways of different IBD-relevant c …
The functional role of the tight junction-associated MARVEL protein MARVELD3 (MD3) in IBD is yet unknown. (i) In colon biopsies from …
MarvelD3 regulates the c-Jun N-terminal kinase pathway during eye development in Xenopus.
Vacca B, Sanchez-Heras E, Steed E, Balda MS, Ohnuma SI, Sasai N, Mayor R, Matter K. Vacca B, et al. Biol Open. 2016 Nov 15;5(11):1631-1641. doi: 10.1242/bio.018945. Biol Open. 2016. PMID: 27870636 Free PMC article.
However, despite a well-known mechanism, the dialogue between those signals and factors remains to be unveiled. Here, we identify a requirement for MarvelD3, a tight junction transmembrane protein, in eye morphogenesis in Xenopus MarvelD3 depletion led to an abnorma …
However, despite a well-known mechanism, the dialogue between those signals and factors remains to be unveiled. Here, we identify a requirem …
High expression of MARVELD3 as a potential prognostic biomarker for oral squamous cell carcinoma.
Huang K, Meng Y, Lu J, Xu L, Wang S, Wang H, Xu Z. Huang K, et al. Front Genet. 2022 Oct 24;13:1050402. doi: 10.3389/fgene.2022.1050402. eCollection 2022. Front Genet. 2022. PMID: 36353110 Free PMC article.
Univariate and multivariate Cox regression analyses showed that MARVELD3 could serve as an independent contributing factor to poor OSCC prognosis. ...Conclusion: The high expression of MARVELD3 is associated with poor prognosis in OSCC, and MARVELD3 could be …
Univariate and multivariate Cox regression analyses showed that MARVELD3 could serve as an independent contributing factor to poor OS …
MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival.
Steed E, Elbediwy A, Vacca B, Dupasquier S, Hemkemeyer SA, Suddason T, Costa AC, Beaudry JB, Zihni C, Gallagher E, Pierreux CE, Balda MS, Matter K. Steed E, et al. J Cell Biol. 2014 Mar 3;204(5):821-38. doi: 10.1083/jcb.201304115. Epub 2014 Feb 24. J Cell Biol. 2014. PMID: 24567356 Free PMC article.
Expression levels of MarvelD3 inversely correlated with JNK activity, as MarvelD3 recruited MEKK1 to junctions, leading to down-regulation of JNK phosphorylation and inhibition of JNK-regulated transcriptional mechanisms. Interplay between MarvelD3 internaliz …
Expression levels of MarvelD3 inversely correlated with JNK activity, as MarvelD3 recruited MEKK1 to junctions, leading to dow …
Role of tight junction-associated MARVEL protein marvelD3 in migration and epithelial-mesenchymal transition of hepatocellular carcinoma.
Li Y, Li T, Zhou D, Wei J, Li Z, Li X, Jia S, Ouyang Q, Qi S, Chen Z, Zhang B, Yu J, Jia J, Xu A, Huang J. Li Y, et al. Cell Adh Migr. 2021 Dec;15(1):249-260. doi: 10.1080/19336918.2021.1958441. Cell Adh Migr. 2021. PMID: 34338154 Free PMC article.
MarvelD3, a recently identified tight junction membrane protein, could be associated with hepatocellular carcinoma (HCC). ...Finally, we analyzed expression of marvelD3 protein was significantly associated with EMT and the NF-kappaB signaling pathway. ...
MarvelD3, a recently identified tight junction membrane protein, could be associated with hepatocellular carcinoma (HCC). ...Finally,
Spatio-temporal expression pattern and role of the tight junction protein MarvelD3 in pancreas development and function.
Heymans C, Delcorte O, Spourquet C, Villacorte-Tabelin M, Dupasquier S, Achouri Y, Mahibullah S, Lemoine P, Balda MS, Matter K, Pierreux CE. Heymans C, et al. Sci Rep. 2021 Jul 15;11(1):14519. doi: 10.1038/s41598-021-93654-2. Sci Rep. 2021. PMID: 34267243 Free PMC article.
In Xenopus laevis, MarvelD3 morphants present differentiation defects of several ectodermal derivatives. ...Surprisingly, inactivation of MarvelD3 in mice did not alter development and differentiation of the pancreatic tissue. ...
In Xenopus laevis, MarvelD3 morphants present differentiation defects of several ectodermal derivatives. ...Surprisingly, inactivatio …
Control of neural crest induction by MarvelD3-mediated attenuation of JNK signalling.
Vacca B, Sanchez-Heras E, Steed E, Busson SL, Balda MS, Ohnuma SI, Sasai N, Mayor R, Matter K. Vacca B, et al. Sci Rep. 2018 Jan 19;8(1):1204. doi: 10.1038/s41598-018-19579-5. Sci Rep. 2018. PMID: 29352236 Free PMC article.
Using embryos and explant cultures combined with a small molecule inhibitor or mutant mRNAs, we show that MarvelD3 is required to attenuate JNK signalling during neural crest induction and that inhibition of JNK pathway activation is sufficient to rescue the phenotype indu …
Using embryos and explant cultures combined with a small molecule inhibitor or mutant mRNAs, we show that MarvelD3 is required to att …
Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family.
Steed E, Rodrigues NT, Balda MS, Matter K. Steed E, et al. BMC Cell Biol. 2009 Dec 22;10:95. doi: 10.1186/1471-2121-10-95. BMC Cell Biol. 2009. PMID: 20028514 Free PMC article.
MarvelD3 co-localises with occludin at tight junctions in intestinal and corneal epithelial cells. ...However, MarvelD3 functions as a determinant of epithelial paracellular permeability properties....
MarvelD3 co-localises with occludin at tight junctions in intestinal and corneal epithelial cells. ...However, MarvelD3 functi
36 results