MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival.
Steed E, Elbediwy A, Vacca B, Dupasquier S, Hemkemeyer SA, Suddason T, Costa AC, Beaudry JB, Zihni C, Gallagher E, Pierreux CE, Balda MS, Matter K.
Steed E, et al.
J Cell Biol. 2014 Mar 3;204(5):821-38. doi: 10.1083/jcb.201304115. Epub 2014 Feb 24.
J Cell Biol. 2014.
PMID: 24567356
Free PMC article.
Expression levels of MarvelD3 inversely correlated with JNK activity, as MarvelD3 recruited MEKK1 to junctions, leading to down-regulation of JNK phosphorylation and inhibition of JNK-regulated transcriptional mechanisms. Interplay between MarvelD3 internaliz …
Expression levels of MarvelD3 inversely correlated with JNK activity, as MarvelD3 recruited MEKK1 to junctions, leading to dow …