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Genome-Wide Analysis of MAMSTR Transcription Factor-Binding Sites via ChIP-Seq in Porcine Skeletal Muscle Fibroblasts.
Li C, Zhang Z, Wei Y, Qi K, Dou Y, Song C, Liu Y, Li X, Li X, Wang K, Qiao R, Yang F, Han X. Li C, et al. Animals (Basel). 2023 May 23;13(11):1731. doi: 10.3390/ani13111731. Animals (Basel). 2023. PMID: 37889674 Free PMC article.
Myocyte enhancer factor-2-activating motif and SAP domain-containing transcriptional regulator (MAMSTR) regulates its downstream through binding in its promoter regions. ...The results showed that MAMSTR was associated with 1506 peaks, which were annotated as 962 di …
Myocyte enhancer factor-2-activating motif and SAP domain-containing transcriptional regulator (MAMSTR) regulates its downstream thro …
Causal associations and shared genetics between hypertension and COVID-19.
Baranova A, Cao H, Zhang F. Baranova A, et al. J Med Virol. 2023 Apr;95(4):e28698. doi: 10.1002/jmv.28698. J Med Virol. 2023. PMID: 36951353
Hypertension and hospitalized COVID-19 have three overlapping loci and share eight protein-coding risk genes, including ABO, CSF2, FUT2, IZUMO1, MAMSTR, NPNT, RASIP1, and WNT3. Molecular pathway analysis suggests that hypertension may promote the development of COVID-19 th …
Hypertension and hospitalized COVID-19 have three overlapping loci and share eight protein-coding risk genes, including ABO, CSF2, FUT2, IZU …
Pax7, Pax3 and Mamstr genes are involved in skeletal muscle impaired regeneration of dy2J/dy2J mouse model of Lama2-CMD.
Yanay N, Elbaz M, Konikov-Rozenman J, Elgavish S, Nevo Y, Fellig Y, Rabie M, Mitrani-Rosenbaum S, Nevo Y. Yanay N, et al. Hum Mol Genet. 2019 Oct 15;28(20):3369-3390. doi: 10.1093/hmg/ddz180. Hum Mol Genet. 2019. PMID: 31348492
Interestingly, significant downregulation of Pax7 was detected in dy2J/dy2J compared to upregulation of this key regeneration gene in mdx mice. Pax3 and Mamstr genes were also downregulated in dy2J/dy2J compared to WT mice. ...
Interestingly, significant downregulation of Pax7 was detected in dy2J/dy2J compared to upregulation of this key regeneration gene in mdx mi …
Emerging roles of the myocardin family of proteins in lipid and glucose metabolism.
Swärd K, Stenkula KG, Rippe C, Alajbegovic A, Gomez MF, Albinsson S. Swärd K, et al. J Physiol. 2016 Sep 1;594(17):4741-52. doi: 10.1113/JP271913. Epub 2016 May 10. J Physiol. 2016. PMID: 27060572 Free PMC article. Review.
This coactivator family includes the protein myocardin (MYOCD), the myocardin-related transcription factors A and B (MRTF-A/MKL1 and MRTF-B/MKL2) and MASTR (MAMSTR). Here we discuss growing evidence that SRF-driven transcription is controlled by extracellular glucose throu …
This coactivator family includes the protein myocardin (MYOCD), the myocardin-related transcription factors A and B (MRTF-A/MKL1 and MRTF-B/ …
Genome-Wide Association Study Identifies New Risk Loci for Progression of Schistosomiasis Among the Chinese Population.
Zhou M, Xue C, Wu Z, Wu X, Li M. Zhou M, et al. Front Cell Infect Microbiol. 2022 Apr 12;12:871545. doi: 10.3389/fcimb.2022.871545. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35493725 Free PMC article.
These were significantly associated with serum levels of hyaluronic acid (HA). In addition, RASIP1 and MAMSTR at 19q13.33 (index rs62132778, P = 1.72 10(-7)) were significantly associated with serum levels of aspartate aminotransferase (AST), and TPM1 at 15q22.2 (index rs1 …
These were significantly associated with serum levels of hyaluronic acid (HA). In addition, RASIP1 and MAMSTR at 19q13.33 (index rs62 …
Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer's disease.
Zhang L, Silva TC, Young JI, Gomez L, Schmidt MA, Hamilton-Nelson KL, Kunkle BW, Chen X, Martin ER, Wang L. Zhang L, et al. Nat Commun. 2020 Nov 30;11(1):6114. doi: 10.1038/s41467-020-19791-w. Nat Commun. 2020. PMID: 33257653 Free PMC article.
Our analysis identified differentially methylated genes such as MAMSTR, AGAP2, and AZU1. The most significant DMR identified is located on the MAMSTR gene, which encodes a cofactor that stimulates MEF2C. ...
Our analysis identified differentially methylated genes such as MAMSTR, AGAP2, and AZU1. The most significant DMR identified is locat …
Integration of RNA-seq and ATAC-seq identifies muscle-regulated hub genes in cattle.
Wang J, Li B, Yang X, Liang C, Raza SHA, Pan Y, Zhang K, Zan L. Wang J, et al. Front Vet Sci. 2022 Aug 11;9:925590. doi: 10.3389/fvets.2022.925590. eCollection 2022. Front Vet Sci. 2022. PMID: 36032309 Free PMC article.
Including CAPN3, ACTN2, MB, MYOM3, SRL, CKM, ALPK3, MAP3K20, UBE2G1, NEURL2, CAND2, DOT1L, HRC, MAMSTR, FSD2, LRRC2, LSMEM1, SLC29A2, FHL3, KLHL41, ATXN7L2, and PDRG1. ...
Including CAPN3, ACTN2, MB, MYOM3, SRL, CKM, ALPK3, MAP3K20, UBE2G1, NEURL2, CAND2, DOT1L, HRC, MAMSTR, FSD2, LRRC2, LSMEM1, SLC29A2, …
FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses.
Ahluwalia TS, Eliasen AU, Sevelsted A, Pedersen CT, Stokholm J, Chawes B, Bork-Jensen J, Grarup N, Pedersen O, Hansen T, Linneberg A, Sharma A, Weiss ST, Evans MD, Jackson DJ, Morin A, Krogfelt KA, Schjørring S, Mortensen PB, Hougaard DM, Bybjerg-Grauholm J, Bækvad-Hansen M, Mors O, Nordentoft M, Børglum AD, Werge T, Agerbo E, Gern JE, Lemanske RF Jr, Ober C, Pedersen AG, Bisgaard H, Bønnelykke K. Ahluwalia TS, et al. Nat Commun. 2020 Dec 16;11(1):6398. doi: 10.1038/s41467-020-19814-6. Nat Commun. 2020. PMID: 33328473 Free PMC article.
The discovery analysis comprises 2866 children experiencing severe asthma exacerbation between ages 2 and 6 years, and 65,415 non-asthmatic controls, and we replicate findings in 918 children from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC) birth cohorts. W …
The discovery analysis comprises 2866 children experiencing severe asthma exacerbation between ages 2 and 6 years, and 65,415 non-asthmatic …
An Analysis of a Transposable Element Expression Atlas during 27 Developmental Stages in Porcine Skeletal Muscle: Unveiling Molecular Insights into Pork Production Traits.
Wang C, Lei B, Liu Y. Wang C, et al. Animals (Basel). 2023 Nov 20;13(22):3581. doi: 10.3390/ani13223581. Animals (Basel). 2023. PMID: 38003198 Free PMC article.
This network highlighted several established candidate genes associated with muscle-relevant traits, including HES6, CHRNG, ACTC1, CHRND, MAMSTR, and PER2, as well as novel genes like ENSSSCG00000005518, ENSSSCG00000033601, and PIEZO2. ...
This network highlighted several established candidate genes associated with muscle-relevant traits, including HES6, CHRNG, ACTC1, CHRND, …