Histopathological study of lesions of nose and paranasal sinuses

Indian J Otolaryngol Head Neck Surg. 2012 Sep;64(3):275-9. doi: 10.1007/s12070-011-0286-7. Epub 2011 Sep 10.

Abstract

(1) To study the incidence of benign and malignant lesions of nose and paranasal sinuses (PNS). (2) To study various lesions in reference to sex differences and symptomatology. (3) To compare the findings of the study with other authors. The study was conducted over a period of 7 years both retrospectively and prospectively. The formalin fixed specimens were received with complete clinical and radiological features. Routine gross examination and required number of sections were taken and stained with hematoxylin and eosin. Periodic acid Schiffs and reticulin stains were used wherever necessary. The incidence of lesions in nasal cavity (NC) and PNS was 16.71 cases per year, non-neoplastic lesions constituted 86% of these cases and their incidence was 14.42% and neoplastic lesions constituted 12%. All the cases were carefully examined histopathologically and it was found that the region was affected by variety of lesions. Among 117 cases, 101 were non-neoplastic and 16 were neoplastic. The commonest site was NC, followed by PNS. They occur commonly in second and third decades with predominance in males. Amongst the non-inflammatory lesion, nasal polyp is the commonest lesion followed by rhinoscleroma and rhinosporidiosis. The common age group is second and third decades, with male predominance. Amongst benign neoplastic lesions capillary haemangioma was common followed by inverted papilloma. The common age group is second and third decades, with male predominance. Malignant lesions were comparatively less to that of benign lesions.

Keywords: Nose and paranasal sinuses; Rhinoscleroma; Rhinosporidiosis.