Luciferin derivatives for enhanced in vitro and in vivo bioluminescence assays.
Biochemistry. 2006.
PMID: 16964971
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Luciferin derivatives for enhanced in vitro and in vivo bioluminescence assays.
Shinde R, Perkins J, Contag CH.
Shinde R, et al.
Biochemistry. 2006 Sep 19;45(37):11103-12. doi: 10.1021/bi060475o.
Biochemistry. 2006.
PMID: 16964971
In vivo bioluminescence imaging has become a cornerstone technology for preclinical molecular imaging. ...Glycine-d-aminoluciferin had a longer in vivo circulation time than the other two substrates. The ability to assay luciferase in …
In vivo bioluminescence imaging has become a cornerstone technology for preclinical molecular imaging. ...Glycine-d-ami …
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In vitro and in vivo bioluminescence reporter gene imaging of human embryonic stem cells.
Wilson K, Yu J, Lee A, Wu JC.
Wilson K, et al.
J Vis Exp. 2008 May 2;(14):740. doi: 10.3791/740.
J Vis Exp. 2008.
PMID: 19066577
Free PMC article.
A major advance in molecular imaging has been the extension of noninvasive reporter gene assays from molecular and cellular biology into in vivo multi-modality imaging platforms. ...Transcription and translation of reporter genes into bioactive proteins is th …
A major advance in molecular imaging has been the extension of noninvasive reporter gene assays from molecular and cellular biology i …
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Identification of inhibitors of ABCG2 by a bioluminescence imaging-based high-throughput assay.
Zhang Y, Byun Y, Ren YR, Liu JO, Laterra J, Pomper MG.
Zhang Y, et al.
Cancer Res. 2009 Jul 15;69(14):5867-75. doi: 10.1158/0008-5472.CAN-08-4866. Epub 2009 Jun 30.
Cancer Res. 2009.
PMID: 19567678
Free PMC article.
This assay exploits our finding that d-luciferin, the substrate of firefly luciferase (fLuc), is a specific substrate of ABCG2, and ABCG2 inhibitors block the export of d-luciferin and enhance bioluminescence signal by increasing intracellular d …
This assay exploits our finding that d-luciferin, the substrate of firefly luciferase (fLuc), is a specific substrate of ABCG2 …
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Coix Seed Extract Enhances the Anti-Pancreatic Cancer Efficacy of Gemcitabine through Regulating ABCB1- and ABCG2-Mediated Drug Efflux: A Bioluminescent Pharmacokinetic and Pharmacodynamic Study.
Qian Y, Xiong Y, Feng D, Wu Y, Zhang X, Chen L, Gu M.
Qian Y, et al.
Int J Mol Sci. 2019 Oct 23;20(21):5250. doi: 10.3390/ijms20215250.
Int J Mol Sci. 2019.
PMID: 31652737
Free PMC article.
We also investigated the potential association between the intracellular bioluminescent pharmacokinetic profiles and the anti-tumor efficacy of the coix seed extract and gemcitabine against pancreatic cancer cells in vitro and in vivo. ...The Pe …
We also investigated the potential association between the intracellular bioluminescent pharmacokinetic profiles and the anti-tumor e …
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