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Effect of Torsemide vs Furosemide After Discharge on All-Cause Mortality in Patients Hospitalized With Heart Failure: The TRANSFORM-HF Randomized Clinical Trial.
Mentz RJ, Anstrom KJ, Eisenstein EL, Sapp S, Greene SJ, Morgan S, Testani JM, Harrington AH, Sachdev V, Ketema F, Kim DY, Desvigne-Nickens P, Pitt B, Velazquez EJ; TRANSFORM-HF Investigators. Mentz RJ, et al. JAMA. 2023 Jan 17;329(3):214-223. doi: 10.1001/jama.2022.23924. JAMA. 2023. PMID: 36648467 Free PMC article. Clinical Trial.
IMPORTANCE: Although furosemide is the most commonly used loop diuretic in patients with heart failure, some studies suggest a potential benefit for torsemide. OBJECTIVE: To determine whether torsemide results in decreased mortality compared wit …
IMPORTANCE: Although furosemide is the most commonly used loop diuretic in patients with heart failure, s …
Effect of Torsemide Versus Furosemide on Symptoms and Quality of Life Among Patients Hospitalized for Heart Failure: The TRANSFORM-HF Randomized Clinical Trial.
Greene SJ, Velazquez EJ, Anstrom KJ, Clare RM, DeWald TA, Psotka MA, Ambrosy AP, Stevens GR, Rommel JJ, Alexy T, Ketema F, Kim DY, Desvigne-Nickens P, Pitt B, Eisenstein EL, Mentz RJ; TRANSFORM-HF Investigators. Greene SJ, et al. Circulation. 2023 Jul 11;148(2):124-134. doi: 10.1161/CIRCULATIONAHA.123.064842. Epub 2023 May 22. Circulation. 2023. PMID: 37212600 Clinical Trial.
As prespecified secondary end points, the TRANSFORM-HF trial (Torsemide Comparison With Furosemide for Management of Heart Failure) compared the effect of torsemide versus furosemide on patient-reported outcomes among patients with HF. ...The ef …
As prespecified secondary end points, the TRANSFORM-HF trial (Torsemide Comparison With Furosemide for Management of Heart Failure …
Loop Diuretic Use is Associated With Adverse Clinical Outcomes in Acute Myocardial Infarction Patients With Low Volume Status.
Kawai T, Nakatani D, Watanabe T, Yamada T, Morita T, Sakata Y, Hikoso S, Mizuno H, Suna S, Kitamura T, Okada K, Dohi T, Sotomi Y, Sunaga A, Kida H, Oeun B, Sato T, Sato H, Hori M, Komuro I, Fukunami M, Sakata Y; Osaka Acute Coronary Insufficiency Study (OACIS) Investigators. Kawai T, et al. Curr Probl Cardiol. 2022 Nov;47(11):101326. doi: 10.1016/j.cpcardiol.2022.101326. Epub 2022 Jul 20. Curr Probl Cardiol. 2022. PMID: 35870545 Review.
There was no heterogeneity in the increased risk of the primary endpoints between various patient characteristics and loop diuretic use in the matched cohorts. In conclusion, prescription of loop diuretics at discharge was associated with …
There was no heterogeneity in the increased risk of the primary endpoints between various patient characteristics and loop …
Association of loop diuretics use and dose with outcomes in outpatients with heart failure: a systematic review and meta-analysis of observational studies involving 96,959 patients.
Kapelios CJ, Bonou Μ, Malliaras K, Athanasiadi E, Vakrou S, Skouloudi M, Masoura C, Barbetseas J. Kapelios CJ, et al. Heart Fail Rev. 2022 Jan;27(1):147-161. doi: 10.1007/s10741-020-09995-z. Heart Fail Rev. 2022. PMID: 32564330 Review.
There is ongoing controversy regarding the association between loop diuretics (LD), especially in high doses, and adverse clinical outcomes in outpatients with heart failure (HF). ...Again, this association remained significant aft …
There is ongoing controversy regarding the association between loop diuretics (LD), especially in high doses, and adverse …
Torsemide Versus Furosemide After Discharge in Patients Hospitalized With Heart Failure Across the Spectrum of Ejection Fraction: Findings From TRANSFORM-HF.
Kapelios CJ, Greene SJ, Mentz RJ, Ikeaba U, Wojdyla D, Anstrom KJ, Eisenstein EL, Pitt B, Velazquez EJ, Fang JC; TRANSFORM-HF Investigators. Kapelios CJ, et al. Circ Heart Fail. 2024 Mar;17(3):e011246. doi: 10.1161/CIRCHEARTFAILURE.123.011246. Epub 2024 Mar 4. Circ Heart Fail. 2024. PMID: 38436075 Clinical Trial.
BACKGROUND: The TRANSFORM-HF trial (Torsemide Comparison With Furosemide for Management of Heart Failure) found no significant difference in all-cause mortality or hospitalization among patients randomized to a strategy of torsemide versus furosemide f …
BACKGROUND: The TRANSFORM-HF trial (Torsemide Comparison With Furosemide for Management of Heart Failure) found no significant …
Loop diuretic use at discharge is associated with adverse outcomes in hospitalized patients with heart failure: a report from the Japanese cardiac registry of heart failure in cardiology (JCARE-CARD).
Hamaguchi S, Kinugawa S, Tsuchihashi-Makaya M, Goto D, Yamada S, Yokoshiki H, Takeshita A, Tsutsui H; JCARE-CARD Investigators. Hamaguchi S, et al. Circ J. 2012;76(8):1920-7. doi: 10.1253/circj.cj-11-1196. Epub 2012 May 26. Circ J. 2012. PMID: 22665070 Free article.
We thus determined the effects of loop diuretic use at discharge on long-term mortality and rehospitalization among patients hospitalized with HF. ...CONCLUSIONS: Among patients hospitalized with worsening HF, loop diuret …
We thus determined the effects of loop diuretic use at discharge on long-term mortality and rehospitalization among …
Early diuretic strategies and the association with In-hospital and Post-discharge outcomes in acute heart failure.
Fudim M, Spates T, Sun JL, Kittipibul V, Testani JM, Starling RC, Tang WHW, Hernandez AF, Felker GM, O'Connor CM, Mentz RJ. Fudim M, et al. Am Heart J. 2021 Sep;239:110-119. doi: 10.1016/j.ahj.2021.05.011. Epub 2021 May 27. Am Heart J. 2021. PMID: 34052212 Clinical Trial.
BACKGROUND: Decongestion is a primary goal during hospitalizations for decompensated heart failure (HF). However, data surrounding the preferred route and strategy of diuretic administration are limited with varying results in prior studies. ...CONCLUS …
BACKGROUND: Decongestion is a primary goal during hospitalizations for decompensated heart failure (HF). However, data …
Can Torsemide and Combination of Loop Diuretics Improve Mortality in Patients with Chronic Heart Failure After Discharge?
Yao Y, Zhang J, Zhang Y, Zhang R. Yao Y, et al. Int Heart J. 2018 Jul 31;59(4):813-820. doi: 10.1536/ihj.17-522. Epub 2018 Jun 6. Int Heart J. 2018. PMID: 29877310 Free article.
The aim of this study was to investigate the effect on mortality of torsemide and a combination of loop diuretics (furosemide + torsemide) in contemporary practice in patients with chronic heart failure (HF).We investigated patients with HF in t …
The aim of this study was to investigate the effect on mortality of torsemide and a combination of loop diuretics (furosemide + torse …
Loop Diuretic Prescription and Long-Term Outcomes in Heart Failure: Association Modification by Congestion.
Faselis C, Lam PH, Patel S, Arundel C, Filippatos G, Deedwania P, Zile MR, Wopperer S, Nguyen T, Allman RM, Fonarow GC, Ahmed A. Faselis C, et al. Am J Med. 2021 Jun;134(6):797-804. doi: 10.1016/j.amjmed.2020.11.019. Epub 2021 Jan 28. Am J Med. 2021. PMID: 33359271
In hospitalized patients with heart failure, a discharge loop diuretic prescription has been shown to be associated with improved 30-day outcomes, which appears to be more pronounced in subgroups with congestion. ...I …
In hospitalized patients with heart failure, a discharge loop diuretic prescription has bee …
Outcomes Associated With a Strategy of Adjuvant Metolazone or High-Dose Loop Diuretics in Acute Decompensated Heart Failure: A Propensity Analysis.
Brisco-Bacik MA, Ter Maaten JM, Houser SR, Vedage NA, Rao V, Ahmad T, Wilson FP, Testani JM. Brisco-Bacik MA, et al. J Am Heart Assoc. 2018 Sep 18;7(18):e009149. doi: 10.1161/JAHA.118.009149. J Am Heart Assoc. 2018. PMID: 30371181 Free PMC article.
Background In acute decompensated heart failure, guidelines recommend increasing loop diuretic dose or adding a thiazide diuretic when diuresis is inadequate. ...Methods and Results Patients admitted to 3 hospitals using a common e …
Background In acute decompensated heart failure, guidelines recommend increasing loop diuretic dose or adding a …
24 results