Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 2
2001 1
2004 1
2006 5
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

9 results

Results by year

Filters applied: . Clear all
Page 1
Potent 4-amino-5-azaindole factor VIIa inhibitors.
Hu H, Kolesnikov A, Riggs JR, Wesson KE, Stephens R, Leahy EM, Shrader WD, Sprengeler PA, Green MJ, Sanford E, Nguyen M, Gjerstad E, Cabuslay R, Young WB. Hu H, et al. Among authors: leahy em. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4567-70. doi: 10.1016/j.bmcl.2006.06.016. Epub 2006 Jun 21. Bioorg Med Chem Lett. 2006. PMID: 16793264
Novel 5-azaindole factor VIIa inhibitors.
Riggs JR, Hu H, Kolesnikov A, Leahy EM, Wesson KE, Shrader WD, Vijaykumar D, Wahl TA, Tong Z, Sprengeler PA, Green MJ, Yu C, Katz BA, Sanford E, Nguyen M, Cabuslay R, Young WB. Riggs JR, et al. Among authors: leahy em. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3197-200. doi: 10.1016/j.bmcl.2006.03.049. Epub 2006 Apr 18. Bioorg Med Chem Lett. 2006. PMID: 16621549
Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases.
Somoza JR, Skene RJ, Katz BA, Mol C, Ho JD, Jennings AJ, Luong C, Arvai A, Buggy JJ, Chi E, Tang J, Sang BC, Verner E, Wynands R, Leahy EM, Dougan DR, Snell G, Navre M, Knuth MW, Swanson RV, McRee DE, Tari LW. Somoza JR, et al. Among authors: leahy em. Structure. 2004 Jul;12(7):1325-34. doi: 10.1016/j.str.2004.04.012. Structure. 2004. PMID: 15242608 Free article.
Factor VIIa inhibitors: improved pharmacokinetic parameters.
Kolesnikov A, Rai R, Young WB, Mordenti J, Liu L, Torkelson S, Shrader WD, Leahy EM, Hu H, Gjerstad E, Janc J, Katz BA, Sprengeler PA. Kolesnikov A, et al. Among authors: leahy em. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2243-6. doi: 10.1016/j.bmcl.2006.01.037. Epub 2006 Feb 7. Bioorg Med Chem Lett. 2006. PMID: 16455251
Optimization of a screening lead for factor VIIa/TF.
Young WB, Kolesnikov A, Rai R, Sprengeler PA, Leahy EM, Shrader WD, Sangalang J, Burgess-Henry J, Spencer J, Elrod K, Cregar L. Young WB, et al. Among authors: leahy em. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2253-6. doi: 10.1016/s0960-894x(01)00420-6. Bioorg Med Chem Lett. 2001. PMID: 11527709
Efforts toward oral bioavailability in factor VIIa inhibitors.
Vijaykumar D, Rai R, Shaghafi M, Ton T, Torkelson S, Leahy EM, Riggs JR, Hu H, Sprengeler PA, Shrader WD, O'Bryan C, Cabuslay R, Sanford E, Gjerstadt E, Liu L, Sukbuntherng J, Young WB. Vijaykumar D, et al. Among authors: leahy em. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3829-32. doi: 10.1016/j.bmcl.2006.04.018. Epub 2006 May 2. Bioorg Med Chem Lett. 2006. PMID: 16650987
Factor VIIa inhibitors: chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in an arterial baboon thrombosis model.
Young WB, Mordenti J, Torkelson S, Shrader WD, Kolesnikov A, Rai R, Liu L, Hu H, Leahy EM, Green MJ, Sprengeler PA, Katz BA, Yu C, Janc JW, Elrod KC, Marzec UM, Hanson SR. Young WB, et al. Among authors: leahy em. Bioorg Med Chem Lett. 2006 Apr 1;16(7):2037-41. doi: 10.1016/j.bmcl.2005.12.059. Epub 2006 Jan 18. Bioorg Med Chem Lett. 2006. PMID: 16412633