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Proteomics Study on the Cerebrospinal Fluid of Patients with Encephalitis.
Xiong LL, Xue LL, Chen YJ, Du RL, Wang Q, Wen S, Zhou L, Liu T, Wang TH, Yu CY. Xiong LL, et al. ACS Omega. 2021 Jun 17;6(25):16288-16296. doi: 10.1021/acsomega.1c00367. eCollection 2021 Jun 29. ACS Omega. 2021. PMID: 34235299 Free PMC article.
Furthermore, four downregulated encephalitis-related neurological synapse proteins were identified after screening for differentially expressed proteins, including NRXN3, NFASC, LRRC4B, and NLGN2. The result of ELISA further verified that the expression of NLGN2 and LRR …
Furthermore, four downregulated encephalitis-related neurological synapse proteins were identified after screening for differentially expres …
NGL-3-induced presynaptic differentiation of hippocampal neurons in an afadin-dependent, nectin-1-independent manner.
Maruo T, Mandai K, Miyata M, Sakakibara S, Wang S, Sai K, Itoh Y, Kaito A, Fujiwara T, Mizoguchi A, Takai Y. Maruo T, et al. Genes Cells. 2017 Aug;22(8):742-755. doi: 10.1111/gtc.12510. Epub 2017 Jul 11. Genes Cells. 2017. PMID: 28695613 Free article.
We investigated here using a co-culture system with cultured hippocampal neurons and non-neuronal COS-7 cells expressing synaptogenic cell adhesion molecules (CAMs) whether afadin is involved in the presynaptic differentiation of hippocampal synapses. Postsynaptic CAMs NGL-3 (ali …
We investigated here using a co-culture system with cultured hippocampal neurons and non-neuronal COS-7 cells expressing synaptogenic cell a …
Systematic identification of novel cancer genes through analysis of deep shRNA perturbation screens.
Montazeri H, Coto-Llerena M, Bianco G, Zangene E, Taha-Mehlitz S, Paradiso V, Srivatsa S, de Weck A, Roma G, Lanzafame M, Bolli M, Beerenwinkel N, von Flüe M, Terracciano LM, Piscuoglio S, Ng CKY. Montazeri H, et al. Nucleic Acids Res. 2021 Sep 7;49(15):8488-8504. doi: 10.1093/nar/gkab627. Nucleic Acids Res. 2021. PMID: 34313788 Free PMC article.
Additionally, APSiC discovered tumor-promoting and tumor-suppressive effectors, respectively, for individual cancer types, including genes involved in cell cycle control, Wnt/beta-catenin and hippo signalling pathways. We functionally demonstrated that LRRC4B, a putative n …
Additionally, APSiC discovered tumor-promoting and tumor-suppressive effectors, respectively, for individual cancer types, including genes i …
The plasma peptides of breast versus ovarian cancer.
Dufresne J, Bowden P, Thavarajah T, Florentinus-Mefailoski A, Chen ZZ, Tucholska M, Norzin T, Ho MT, Phan M, Mohamed N, Ravandi A, Stanton E, Slutsky AS, Dos Santos CC, Romaschin A, Marshall JC, Addison C, Malone S, Heyland D, Scheltens P, Killestein J, Teunissen C, Diamandis EP, Siu KWM, Marshall JG. Dufresne J, et al. Clin Proteomics. 2019 Dec 23;16:43. doi: 10.1186/s12014-019-9262-0. eCollection 2019. Clin Proteomics. 2019. PMID: 31889940 Free PMC article.

Many cellular proteins also showed large changes in frequency by Chi Square (chi(2) > 100, p < 0.0001) in the breast cancer samples such as CPEB1, LTBP4, HIF-1A, IGHE, RAB44, NEFM, C19orf82, SLC35B1, 1D12A, C8orf34, HIF1A, OCLN, EYA1, HLA-DRB1, LARS, PTPDC1, WWC1, ZNF562, P

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Many cellular proteins also showed large changes in frequency by Chi Square (chi(2) > 100, p < 0.0001) in the breast cancer samples su

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An unbiased expression screen for synaptogenic proteins identifies the LRRTM protein family as synaptic organizers.
Linhoff MW, Laurén J, Cassidy RM, Dobie FA, Takahashi H, Nygaard HB, Airaksinen MS, Strittmatter SM, Craig AM. Linhoff MW, et al. Neuron. 2009 Mar 12;61(5):734-49. doi: 10.1016/j.neuron.2009.01.017. Neuron. 2009. PMID: 19285470 Free PMC article.
Here, we performed an unbiased expression screen for synaptogenic proteins in the coculture assay using custom-made cDNA libraries. Reisolation of NGL-3/LRRC4B and neuroligin-2 accounts for a minority of positive clones, indicating that current understanding of mammalian s …
Here, we performed an unbiased expression screen for synaptogenic proteins in the coculture assay using custom-made cDNA libraries. Reisolat …