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TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs.
Eguchi A, Gonzalez AFGS, Torres-Bigio SI, Koleckar K, Birnbaum F, Zhang JZ, Wang VY, Wu JC, Artandi SE, Blau HM. Eguchi A, et al. Among authors: koleckar k. Proc Natl Acad Sci U S A. 2023 Feb 7;120(6):e2209967120. doi: 10.1073/pnas.2209967120. Epub 2023 Jan 31. Proc Natl Acad Sci U S A. 2023. PMID: 36719921 Free PMC article.
Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes.
Chang ACY, Pardon G, Chang ACH, Wu H, Ong SG, Eguchi A, Ancel S, Holbrook C, Ramunas J, Ribeiro AJS, LaGory EL, Wang H, Koleckar K, Giaccia A, Mack DL, Childers MK, Denning C, Day JW, Wu JC, Pruitt BL, Blau HM. Chang ACY, et al. Among authors: koleckar k. Stem Cell Reports. 2021 Sep 14;16(9):2169-2181. doi: 10.1016/j.stemcr.2021.04.018. Epub 2021 May 20. Stem Cell Reports. 2021. PMID: 34019816 Free PMC article.