Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2006 1
2007 3
2008 2
2009 2
2010 1
2011 1
2012 2
2013 3
2014 1
2015 2
2016 1
2017 8
2018 4
2019 2
2020 2
2021 1
2022 1
2023 1
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

33 results

Results by year

Filters applied: . Clear all
Page 1
Overexpression of kin of IRRE-Like protein 1 (KIRREL) as a prognostic biomarker for breast cancer.
Chen K, Zhao R, Yao G, Liu Z, Shi R, Geng J. Chen K, et al. Pathol Res Pract. 2020 Jul;216(7):153000. doi: 10.1016/j.prp.2020.153000. Epub 2020 May 13. Pathol Res Pract. 2020. PMID: 32534710 Review.
Immunohistochemical results showed that the high expression rate of KIRREL staining in breast cancer was 43.7% (132/302). Moreover, Expression of KIRREL was significantly correlated with Her2 status and survival outcomes of patients. ...CONCLUSIONS: KIRREL wa …
Immunohistochemical results showed that the high expression rate of KIRREL staining in breast cancer was 43.7% (132/302). Moreover, E …
KIRREL promotes the proliferation of gastric cancer cells and angiogenesis through the PI3K/AKT/mTOR pathway.
Wang T, Chen S, Wang Z, Li S, Fei X, Wang T, Zhang M. Wang T, et al. J Cell Mol Med. 2024 Jan;28(1):e18020. doi: 10.1111/jcmm.18020. Epub 2023 Nov 1. J Cell Mol Med. 2024. PMID: 37909722 Free PMC article.
A bioinformatics analysis was conducted to screen for the function and pathway enrichment of KIRREL in gastric cancer. Lentivirus-induced KIRREL silencing in SNU-5 cells and lentivirus-induced KIRREL overexpression in AGS cells were used to study the effect o …
A bioinformatics analysis was conducted to screen for the function and pathway enrichment of KIRREL in gastric cancer. Lentivirus-ind …
Integrated screens uncover a cell surface tumor suppressor gene KIRREL involved in Hippo pathway.
Wang C, Feng X, Su D, Chen Z, Wang S, Tang M, Huang M, Nie L, Zhang H, Li S, Yin L, Johnson RL, Hart T, Chen J. Wang C, et al. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2121779119. doi: 10.1073/pnas.2121779119. Epub 2022 Jun 15. Proc Natl Acad Sci U S A. 2022. PMID: 35704761 Free PMC article.
We found that Kirrel1 loss markedly promoted tumor growth in vivo. Moreover, KIRREL was significantly enriched in a separate CRISPR screen based on a specific Hippo pathway reporter. Further studies revealed that KIRREL binds directly to SAV1 to activate the Hippo t …
We found that Kirrel1 loss markedly promoted tumor growth in vivo. Moreover, KIRREL was significantly enriched in a separate CRISPR s …
Discovery of KIRREL as a biomarker for prognostic stratification of patients with thin melanoma.
Lundgren S, Fagerström-Vahman H, Zhang C, Ben-Dror L, Mardinoglu A, Uhlen M, Nodin B, Jirström K. Lundgren S, et al. Biomark Res. 2019 Jan 14;7:1. doi: 10.1186/s40364-018-0153-8. eCollection 2019. Biomark Res. 2019. PMID: 30675360 Free PMC article.
KIRREL mRNA expression was examined in 103 melanoma cases in The Cancer Genome Atlas (TCGA). ...High expression of KIRREL was significantly associated with several unfavourable clinicopathological factors. ...
KIRREL mRNA expression was examined in 103 melanoma cases in The Cancer Genome Atlas (TCGA). ...High expression of KIRREL was
KIRREL is differentially expressed in adipose tissue from 'fertil+' and 'fertil-' cows: in vitro role in ovary?
Coyral-Castel S, Ramé C, Cognié J, Lecardonnel J, Marthey S, Esquerré D, Hennequet-Antier C, Elis S, Fritz S, Boussaha M, Jaffrézic F, Dupont J. Coyral-Castel S, et al. Reproduction. 2018 Feb;155(2):183-198. doi: 10.1530/REP-17-0649. Epub 2017 Nov 23. Reproduction. 2018. PMID: 29170164
By quantitative PCR and immunoblot we confirmed that adipose tissue KIRREL mRNA and protein were significantly greater expressed in 'fertil+' than in 'fertil-'. KIRREL mRNA is abundant in bovine kidney, adipose tissue, pituitary, and ovary and detectable in hypothal …
By quantitative PCR and immunoblot we confirmed that adipose tissue KIRREL mRNA and protein were significantly greater expressed in ' …
Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors.
Wang J, Vaddadi N, Pak JS, Park Y, Quilez S, Roman CA, Dumontier E, Thornton JW, Cloutier JF, Özkan E. Wang J, et al. Cell Rep. 2021 Nov 2;37(5):109940. doi: 10.1016/j.celrep.2021.109940. Cell Rep. 2021. PMID: 34731636 Free PMC article.
Projections from sensory neurons of olfactory systems coalesce into glomeruli in the brain. The Kirrel receptors are believed to homodimerize via their ectodomains and help separate sensory neuron axons into Kirrel2- or Kirrel3-expressing glomeruli. Here, we present the cr …
Projections from sensory neurons of olfactory systems coalesce into glomeruli in the brain. The Kirrel receptors are believed to homo …
Identification and characterization of novel Kirrel isoform during myogenesis.
Durcan PJ, Al-Shanti N, Stewart CE. Durcan PJ, et al. Physiol Rep. 2013 Aug;1(3):e00044. doi: 10.1002/phy2.44. Epub 2013 Aug 22. Physiol Rep. 2013. PMID: 24303129 Free PMC article.
Our results demonstrate the presence of a novel murine Kirrel isoform containing a truncated cytoplasmic domain which we term Kirrel B. ...Furthermore, chemical inhibition of cell fusion confirmed the inverse expression pattern of Kirrel B protein levels in r …
Our results demonstrate the presence of a novel murine Kirrel isoform containing a truncated cytoplasmic domain which we term Kirr
Overexpression of Kin of IRRE-Like Protein 1 (KIRREL) in Gastric Cancer and Its Clinical Prognostic Significance.
Zhang MJ, Hong YY, Li N. Zhang MJ, et al. Med Sci Monit. 2018 May 2;24:2711-2719. doi: 10.12659/MSM.910386. Med Sci Monit. 2018. PMID: 29717104 Free PMC article.
Immunohistochemical results showed that the high positive rate of KIRREL staining in GC was 61.97% (44/71). Moreover, GC patients with KIRREL mRNA or protein high levels had significantly shorter overall survival times than those with KIRREL mRNA or low prote …
Immunohistochemical results showed that the high positive rate of KIRREL staining in GC was 61.97% (44/71). Moreover, GC patients wit …
A conserved molecular pathway mediates myoblast fusion in insects and vertebrates.
Srinivas BP, Woo J, Leong WY, Roy S. Srinivas BP, et al. Nat Genet. 2007 Jun;39(6):781-6. doi: 10.1038/ng2055. Epub 2007 May 27. Nat Genet. 2007. PMID: 17529975
In vertebrates, mechanisms controlling this essential step in myogenesis remain poorly understood. Here we provide evidence that Kirrel, a homolog of receptor proteins that organize myoblast fusion in Drosophila melanogaster, is necessary for muscle precursor fusion in zeb …
In vertebrates, mechanisms controlling this essential step in myogenesis remain poorly understood. Here we provide evidence that Kirrel
33 results