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Distinguishing colorectal adenoma from hyperplastic polyp by WNT2 expression.
Wang B, Wang X, Tseng Y, Huang M, Luo F, Zhang J, Liu J. Wang B, et al. J Clin Lab Anal. 2021 Oct;35(10):e23961. doi: 10.1002/jcla.23961. Epub 2021 Sep 3. J Clin Lab Anal. 2021. PMID: 34477243 Free PMC article.
The top 10 up-regulated genes were DLX5, MMP10, TAC1, ACAN, TAS2R38, WNT2, PHYHIPL, DKK4, DUSP27, and ABCA12. The top 10 down-regulated genes were SFRP2, CHRDL1, KBTBD12, RERGL, DPP10, CLCA4, GREM2, TMIGD1, FEV, and OTOP3. Wnt signaling pathway and extracellular matrix (EC …
The top 10 up-regulated genes were DLX5, MMP10, TAC1, ACAN, TAS2R38, WNT2, PHYHIPL, DKK4, DUSP27, and ABCA12. The top 10 down-regulated gene …
Genetic Susceptibility to Periodontal Disease in Down Syndrome: A Case-Control Study.
Fernández M, de Coo A, Quintela I, García E, Diniz-Freitas M, Limeres J, Diz P, Blanco J, Carracedo Á, Cruz R. Fernández M, et al. Int J Mol Sci. 2021 Jun 10;22(12):6274. doi: 10.3390/ijms22126274. Int J Mol Sci. 2021. PMID: 34200970 Free PMC article.
C12orf74 (rs4315121, p = 9.85 10(-5), OR = 8.84), LOC101930064 (rs4814890, p = 9.61 10(-5), OR = 0.13), KBTBD12 (rs1549874, p = 8.27 10(-5), OR = 0.08), PIWIL1 (rs11060842, p = 7.82 10(-5), OR = 9.05) and C16orf82 (rs62030877, p = 8.92 10(-5), OR = 0.14) showed a higher pr …
C12orf74 (rs4315121, p = 9.85 10(-5), OR = 8.84), LOC101930064 (rs4814890, p = 9.61 10(-5), OR = 0.13), KBTBD12 (rs1549874, p = 8.27 …
Frailty Index associates with GRIN2B in two representative samples from the United States and the United Kingdom.
Mekli K, Stevens A, Marshall AD, Arpawong TE, Phillips DF, Tampubolon G, Lee J, Prescott CA, Nazroo JY, Pendleton N. Mekli K, et al. PLoS One. 2018 Nov 26;13(11):e0207824. doi: 10.1371/journal.pone.0207824. eCollection 2018. PLoS One. 2018. PMID: 30475886 Free PMC article.
We also report a nominal replication: the rs7134291 A allele was significantly associated with a decrease in the square-root transformed FI score (Discovery sample: beta = -0.01021, p = 1.85E-06, Replication sample: beta = -0.005013, p = 0.03433). These hits represent the KBTB …
We also report a nominal replication: the rs7134291 A allele was significantly associated with a decrease in the square-root transformed FI …