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Page 1
Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion.
Fujino T, Asaba H, Kang MJ, Ikeda Y, Sone H, Takada S, Kim DH, Ioka RX, Ono M, Tomoyori H, Okubo M, Murase T, Kamataki A, Yamamoto J, Magoori K, Takahashi S, Miyamoto Y, Oishi H, Nose M, Okazaki M, Usui S, Imaizumi K, Yanagisawa M, Sakai J, Yamamoto TT. Fujino T, et al. Among authors: ioka rx. Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):229-34. doi: 10.1073/pnas.0133792100. Epub 2002 Dec 30. Proc Natl Acad Sci U S A. 2003. PMID: 12509515 Free PMC article.
A Kruppel-like factor KLF15 contributes fasting-induced transcriptional activation of mitochondrial acetyl-CoA synthetase gene AceCS2.
Yamamoto J, Ikeda Y, Iguchi H, Fujino T, Tanaka T, Asaba H, Iwasaki S, Ioka RX, Kaneko IW, Magoori K, Takahashi S, Mori T, Sakaue H, Kodama T, Yanagisawa M, Yamamoto TT, Ito S, Sakai J. Yamamoto J, et al. Among authors: ioka rx. J Biol Chem. 2004 Apr 23;279(17):16954-62. doi: 10.1074/jbc.M312079200. Epub 2004 Feb 10. J Biol Chem. 2004. PMID: 14960588 Free article.
A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice.
Takayasu S, Sakurai T, Iwasaki S, Teranishi H, Yamanaka A, Williams SC, Iguchi H, Kawasawa YI, Ikeda Y, Sakakibara I, Ohno K, Ioka RX, Murakami S, Dohmae N, Xie J, Suda T, Motoike T, Ohuchi T, Yanagisawa M, Sakai J. Takayasu S, et al. Among authors: ioka rx. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7438-43. doi: 10.1073/pnas.0602371103. Epub 2006 Apr 28. Proc Natl Acad Sci U S A. 2006. PMID: 16648250 Free PMC article.
Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome.
Tanaka T, Yamamoto J, Iwasaki S, Asaba H, Hamura H, Ikeda Y, Watanabe M, Magoori K, Ioka RX, Tachibana K, Watanabe Y, Uchiyama Y, Sumi K, Iguchi H, Ito S, Doi T, Hamakubo T, Naito M, Auwerx J, Yanagisawa M, Kodama T, Sakai J. Tanaka T, et al. Among authors: ioka rx. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15924-9. doi: 10.1073/pnas.0306981100. Epub 2003 Dec 15. Proc Natl Acad Sci U S A. 2003. PMID: 14676330 Free PMC article.
SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice.
Iguchi H, Ikeda Y, Okamura M, Tanaka T, Urashima Y, Ohguchi H, Takayasu S, Kojima N, Iwasaki S, Ohashi R, Jiang S, Hasegawa G, Ioka RX, Magoori K, Sumi K, Maejima T, Uchida A, Naito M, Osborne TF, Yanagisawa M, Yamamoto TT, Kodama T, Sakai J. Iguchi H, et al. Among authors: ioka rx. J Biol Chem. 2005 Nov 11;280(45):37669-80. doi: 10.1074/jbc.M505392200. Epub 2005 Sep 7. J Biol Chem. 2005. PMID: 16148004 Free article.
Severe hypercholesterolemia, impaired fat tolerance, and advanced atherosclerosis in mice lacking both low density lipoprotein receptor-related protein 5 and apolipoprotein E.
Magoori K, Kang MJ, Ito MR, Kakuuchi H, Ioka RX, Kamataki A, Kim DH, Asaba H, Iwasaki S, Takei YA, Sasaki M, Usui S, Okazaki M, Takahashi S, Ono M, Nose M, Sakai J, Fujino T, Yamamoto TT. Magoori K, et al. Among authors: ioka rx. J Biol Chem. 2003 Mar 28;278(13):11331-6. doi: 10.1074/jbc.M211987200. Epub 2002 Dec 31. J Biol Chem. 2003. PMID: 12509421 Free article.