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Year Number of Results
1974 1
1980 1
1982 2
1985 1
1988 2
1989 1
1992 1
1993 1
1994 4
1995 3
1996 3
1997 3
2000 2
2001 1
2002 1
2003 1
2004 1
2009 1
2010 1
2012 2
2013 3
2014 1
2016 2
2017 3
2018 3
2019 3
2020 3
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2023 2
2024 3

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57 results

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Page 1
Identification of Hsp90 Inhibitors with Anti-Plasmodium Activity.
Posfai D, Eubanks AL, Keim AI, Lu KY, Wang GZ, Hughes PF, Kato N, Haystead TA, Derbyshire ER. Posfai D, et al. Among authors: hughes pf. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01799-17. doi: 10.1128/AAC.01799-17. Print 2018 Apr. Antimicrob Agents Chemother. 2018. PMID: 29339390 Free PMC article.
Plasmodium PK9 Inhibitors Promote Growth of Liver-Stage Parasites.
Raphemot R, Eubanks AL, Toro-Moreno M, Geiger RA, Hughes PF, Lu KY, Haystead TAJ, Derbyshire ER. Raphemot R, et al. Among authors: hughes pf. Cell Chem Biol. 2019 Mar 21;26(3):411-419.e7. doi: 10.1016/j.chembiol.2018.11.003. Epub 2018 Dec 27. Cell Chem Biol. 2019. PMID: 30595530 Free PMC article.
Targeting Pim Kinases and DAPK3 to Control Hypertension.
Carlson DA, Singer MR, Sutherland C, Redondo C, Alexander LT, Hughes PF, Knapp S, Gurley SB, Sparks MA, MacDonald JA, Haystead TAJ. Carlson DA, et al. Among authors: hughes pf. Cell Chem Biol. 2018 Oct 18;25(10):1195-1207.e32. doi: 10.1016/j.chembiol.2018.06.006. Epub 2018 Jul 19. Cell Chem Biol. 2018. PMID: 30033129 Free PMC article.
Expression of membrane Hsp90 is a molecular signature of T cell activation.
Scarneo SA, Smith AP, Favret J, O'Connell R, Pickeral J, Yang KW, Ferrari G, Loiselle DR, Hughes PF, Kulkarni MM, Gargesha M, Scott B, Roy D, Haynes BF, Kwiek JJ, Haystead TAJ. Scarneo SA, et al. Among authors: hughes pf. Sci Rep. 2022 Oct 27;12(1):18091. doi: 10.1038/s41598-022-22788-8. Sci Rep. 2022. PMID: 36302951 Free PMC article.
TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers.
Damhofer H, Tatar T, Southgate B, Scarneo S, Agger K, Shlyueva D, Uhrbom L, Morrison GM, Hughes PF, Haystead T, Pollard SM, Helin K. Damhofer H, et al. Among authors: hughes pf. Cell Death Dis. 2024 Apr 17;15(4):273. doi: 10.1038/s41419-024-06654-1. Cell Death Dis. 2024. PMID: 38632238 Free PMC article.
Application of immobilized ATP to the study of NLRP inflammasomes.
Liao KC, Sandall CF, Carlson DA, Ulke-Lemée A, Platnich JM, Hughes PF, Muruve DA, Haystead TAJ, MacDonald JA. Liao KC, et al. Among authors: hughes pf. Arch Biochem Biophys. 2019 Jul 30;670:104-115. doi: 10.1016/j.abb.2018.12.031. Epub 2019 Jan 11. Arch Biochem Biophys. 2019. PMID: 30641048
HSP90-Specific nIR Probe Identifies Aggressive Prostate Cancers: Translation from Preclinical Models to a Human Phase I Study.
Osada T, Crosby EJ, Kaneko K, Snyder JC, Ginzel JD, Acharya CR, Yang XY, Polascik TJ, Spasojevic I, Nelson RC, Hobeika A, Hartman ZC, Neckers LM, Rogatko A, Hughes PF, Huang J, Morse MA, Haystead T, Lyerly HK. Osada T, et al. Among authors: hughes pf. Mol Cancer Ther. 2022 Jan;21(1):217-226. doi: 10.1158/1535-7163.MCT-21-0334. Epub 2021 Oct 21. Mol Cancer Ther. 2022. PMID: 34675120 Free PMC article. Clinical Trial.
Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome.
Mansfield CR, Quan B, Chirgwin ME, Eduful B, Hughes PF, Neveu G, Sylvester K, Ryan DH, Kafsack BFC, Haystead TAJ, Leahy JW, Fitzgerald MC, Derbyshire ER. Mansfield CR, et al. Among authors: hughes pf. Cell Chem Biol. 2024 Apr 18;31(4):729-742.e13. doi: 10.1016/j.chembiol.2024.02.008. Epub 2024 Mar 15. Cell Chem Biol. 2024. PMID: 38492573
57 results