Histomorphological transformation of the auricular cartilage after carbon dioxide laser-assisted Mustardé otoplasty. An experimental study

Lasers Med Sci. 2009 May;24(3):433-7. doi: 10.1007/s10103-008-0594-7. Epub 2008 Aug 7.

Abstract

In an experiment on ten rabbits, 8 W carbon dioxide (CO(2)) laser evaporation of the perichondrium, together with one-third to one-half of the thickness of the auricle cartilage, was performed. Subsequently, the auricle was bent in the middle of the vaporized area, the corresponding surfaces of which were then apposed and fixed to each other with mattress sutures. Three months later the auricle specimen was harvested for histopathological evaluation. This revealed that the partially laser-ablated cartilage had grown together in the form of a solid cartilaginous column. The regeneration process, originating from chondroblasts as well as from perichondrium cells, was strongly stimulated by the laser energy delivered.

Publication types

  • Evaluation Study

MeSH terms

  • Animals
  • Chondrogenesis
  • Collagen / biosynthesis
  • Ear Cartilage / anatomy & histology
  • Ear Cartilage / physiology
  • Ear Cartilage / surgery*
  • Ear, External / abnormalities
  • Ear, External / surgery
  • Elastic Tissue / anatomy & histology
  • Humans
  • Laser Therapy / methods*
  • Lasers, Gas / therapeutic use*
  • Models, Animal
  • Rabbits
  • Regeneration
  • Time Factors
  • Wound Healing

Substances

  • Collagen