Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1996 1
1998 1
2000 1
2001 4
2002 6
2003 5
2004 6
2005 5
2006 6
2007 5
2008 3
2009 8
2010 13
2011 9
2012 13
2013 13
2014 10
2015 12
2016 14
2017 22
2018 12
2019 17
2020 10
2021 16
2022 14
2023 18
2024 6

Text availability

Article attribute

Article type

Publication date

Search Results

230 results

Results by year

Filters applied: . Clear all
Page 1
GOPC facilitates the sorting of syndecan-1 in polarized epithelial cells.
Ford C, Burd CG. Ford C, et al. Mol Biol Cell. 2022 Sep 1;33(10):ar86. doi: 10.1091/mbc.E22-05-0165. Epub 2022 Jul 13. Mol Biol Cell. 2022. PMID: 35830596 Free PMC article.
Instead, we reveal that correct basolateral targeting of syndecan-1 requires a full-length PDZ motif in syndecan-1 and the PDZ domain golgin protein GOPC. Moreover, we reveal changes in Golgi morphology elicited by GOPC overexpression. These results suggest that the …
Instead, we reveal that correct basolateral targeting of syndecan-1 requires a full-length PDZ motif in syndecan-1 and the PDZ domain golgin …
GOPC-ROS1 mosaicism in agminated Spitz naevi: report of two cases.
Goto K, Pissaloux D, Kauer F, Huriet V, Tirode F, de la Fouchardière A. Goto K, et al. Virchows Arch. 2021 Sep;479(3):559-564. doi: 10.1007/s00428-020-02992-5. Epub 2021 Mar 17. Virchows Arch. 2021. PMID: 33733342
All these driver gene alterations are mutually exclusive. We report two cases of agminated Spitz naevi with a GOPC-ROS1 fusion. Both cases occurred on the lower limb of young adults. ...These findings suggest the presence of a GOPC-ROS1 mosaicism in melanocytes with …
All these driver gene alterations are mutually exclusive. We report two cases of agminated Spitz naevi with a GOPC-ROS1 fusion. Both …
ROS1-GOPC/FIG: a novel gene fusion in hepatic angiosarcoma.
Marks EI, Pamarthy S, Dizon D, Birnbaum A, Yakirevich E, Safran H, Carneiro BA. Marks EI, et al. Oncotarget. 2019 Jan 4;10(2):245-251. doi: 10.18632/oncotarget.26521. eCollection 2019 Jan 4. Oncotarget. 2019. PMID: 30719217 Free PMC article.
We describe the first reported case of a patient with HAS that harbored a fusion of ROS1 with GOPC/FIG. Similar to other rearrangements involving ROS1, the resulting fusion protein is believed to act as a major driver of carcinogenesis and may be subject to inhibition by d …
We describe the first reported case of a patient with HAS that harbored a fusion of ROS1 with GOPC/FIG. Similar to other rearrangemen …
Scaffolding protein GOPC regulates tight junction structure.
Lu R, Stewart L, Wilson JM. Lu R, et al. Cell Tissue Res. 2015 May;360(2):321-32. doi: 10.1007/s00441-014-2088-1. Epub 2015 Jan 24. Cell Tissue Res. 2015. PMID: 25616555 Free PMC article.
In Madin-Darby canine kidney (MDCK) cells, we find that GOPC localizes to the trans-Golgi network (TGN) but not to the cis- or trans-Golgi cisternae. Colocalization occurs with the early endosome Rab GTPase Rab5 and a TGN/endosome marker Rab14 but not with Rab11, a marker …
In Madin-Darby canine kidney (MDCK) cells, we find that GOPC localizes to the trans-Golgi network (TGN) but not to the cis- or trans- …
GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.
Sievers P, Stichel D, Sill M, Schrimpf D, Sturm D, Selt F, Ecker J, Kazdal D, Miele E, Kranendonk MEG, Tops BBJ, Kohlhof-Meinecke P, Beschorner R, Kramm CM, Hasselblatt M, Reifenberger G, Capper D, Wesseling P, Stenzinger A, Milde T, Korshunov A, Witt O, Pfister SM, Wick W, von Deimling A, Jones DTW, Sahm F. Sievers P, et al. Acta Neuropathol. 2021 Dec;142(6):1065-1069. doi: 10.1007/s00401-021-02369-1. Epub 2021 Sep 18. Acta Neuropathol. 2021. PMID: 34536122 Free PMC article. No abstract available.
Zona Pellucida sperm-binding protein 3 receptor distribution during Gopc(-/-) globozoospermic spermatogenesis.
Bizkarguenaga M, Gomez-Santos L, Madrid JF, Sáez FJ, Alonso E. Bizkarguenaga M, et al. Microsc Res Tech. 2022 Apr;85(4):1454-1464. doi: 10.1002/jemt.24009. Epub 2021 Dec 6. Microsc Res Tech. 2022. PMID: 34870349
In this study, Western blot, RT-PCR, immunohistochemistry and immunogold were done for the localization of the acrosome protein Zona Pellucida sperm-binding protein 3 receptor (ZP3R), also called sp56, in wild type and Gopc(-/-) mice testis. The ZP3R protein was located in …
In this study, Western blot, RT-PCR, immunohistochemistry and immunogold were done for the localization of the acrosome protein Zona Pelluci …
Low expression of the GOPC is a poor prognostic marker in colorectal cancer.
Ohara N, Haraguchi N, Koseki J, Nishizawa Y, Kawai K, Takahashi H, Nishimura J, Hata T, Mizushima T, Yamamoto H, Ishii H, Doki Y, Mori M. Ohara N, et al. Oncol Lett. 2017 Oct;14(4):4483-4490. doi: 10.3892/ol.2017.6817. Epub 2017 Aug 24. Oncol Lett. 2017. PMID: 29085445 Free PMC article.
The present study aimed to clarify the correlation between GOPC expression and prognosis in colorectal cancer. Total RNA was extracted from 153 clinical colorectal cancer specimens and GOPC expression was evaluated using reverse transcription-quantitative polymerase …
The present study aimed to clarify the correlation between GOPC expression and prognosis in colorectal cancer. Total RNA was extracte …
Oncogenic GOPC-ROS1 Fusion Identified in a Congenital Glioblastoma Case.
Whiteway SL, Betts AM, O'Neil ER, Green AL, Gilani A, Orr BA, Mathis DA. Whiteway SL, et al. J Pediatr Hematol Oncol. 2020 Nov;42(8):e813-e818. doi: 10.1097/MPH.0000000000001711. J Pediatr Hematol Oncol. 2020. PMID: 31929384
We report the case of a 7-day-old infant female with congenital GBM found to harbor a GOPC-ROS1 fusion. She underwent surgical resection, moderate-intensity chemotherapy without radiation, and remains disease-free 4 years from completion of therapy. ...
We report the case of a 7-day-old infant female with congenital GBM found to harbor a GOPC-ROS1 fusion. She underwent surgical resect …
The Golgi-Associated PDZ Domain Protein Gopc/PIST Is Required for Synaptic Targeting of mGluR5.
Klüssendorf M, Song I, Schau L, Morellini F, Dityatev A, Koliwer J, Kreienkamp HJ. Klüssendorf M, et al. Mol Neurobiol. 2021 Nov;58(11):5618-5634. doi: 10.1007/s12035-021-02504-9. Epub 2021 Aug 12. Mol Neurobiol. 2021. PMID: 34383253 Free PMC article.
We have analyzed the role of Gopc by knockdown in primary cultured neurons and by generating a conditional Gopc knockout (KO) mouse line. In neurons, targeting of neuroligin 1 (Nlgn1) and metabotropic glutamate receptor 5 (mGlu5) to the plasma membrane was impaired …
We have analyzed the role of Gopc by knockdown in primary cultured neurons and by generating a conditional Gopc knockout (KO) …
230 results