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The MHC class I peptide repertoire is molded by the transcriptome.
Fortier MH, Caron E, Hardy MP, Voisin G, Lemieux S, Perreault C, Thibault P. Fortier MH, et al. J Exp Med. 2008 Mar 17;205(3):595-610. doi: 10.1084/jem.20071985. Epub 2008 Feb 25. J Exp Med. 2008. PMID: 18299400 Free PMC article.
Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules.
de Verteuil D, Muratore-Schroeder TL, Granados DP, Fortier MH, Hardy MP, Bramoullé A, Caron E, Vincent K, Mader S, Lemieux S, Thibault P, Perreault C. de Verteuil D, et al. Among authors: fortier mh. Mol Cell Proteomics. 2010 Sep;9(9):2034-47. doi: 10.1074/mcp.M900566-MCP200. Epub 2010 May 19. Mol Cell Proteomics. 2010. PMID: 20484733 Free PMC article.