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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 5
1990 2
1991 1
1992 5
1993 4
1994 4
1995 3
1996 4
1997 4
1998 8
1999 1
2000 3
2001 2
2002 5
2003 3
2004 1
2005 2
2006 4
2007 3
2008 2
2009 7
2010 3
2011 6
2012 7
2013 7
2014 5
2015 4
2016 4
2017 3
2018 4
2019 2
2020 2
2021 3
2022 2
2023 1
2024 0

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120 results

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Page 1
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.
Souers AJ, Leverson JD, Boghaert ER, Ackler SL, Catron ND, Chen J, Dayton BD, Ding H, Enschede SH, Fairbrother WJ, Huang DC, Hymowitz SG, Jin S, Khaw SL, Kovar PJ, Lam LT, Lee J, Maecker HL, Marsh KC, Mason KD, Mitten MJ, Nimmer PM, Oleksijew A, Park CH, Park CM, Phillips DC, Roberts AW, Sampath D, Seymour JF, Smith ML, Sullivan GM, Tahir SK, Tse C, Wendt MD, Xiao Y, Xue JC, Zhang H, Humerickhouse RA, Rosenberg SH, Elmore SW. Souers AJ, et al. Among authors: fairbrother wj. Nat Med. 2013 Feb;19(2):202-8. doi: 10.1038/nm.3048. Epub 2013 Jan 6. Nat Med. 2013. PMID: 23291630
Targeted degradation via direct 26S proteasome recruitment.
Bashore C, Prakash S, Johnson MC, Conrad RJ, Kekessie IA, Scales SJ, Ishisoko N, Kleinheinz T, Liu PS, Popovych N, Wecksler AT, Zhou L, Tam C, Zilberleyb I, Srinivasan R, Blake RA, Song A, Staben ST, Zhang Y, Arnott D, Fairbrother WJ, Foster SA, Wertz IE, Ciferri C, Dueber EC. Bashore C, et al. Among authors: fairbrother wj. Nat Chem Biol. 2023 Jan;19(1):55-63. doi: 10.1038/s41589-022-01218-w. Epub 2022 Dec 28. Nat Chem Biol. 2023. PMID: 36577875 Free PMC article.
Small-molecule pan-IAP antagonists: a patent review.
Flygare JA, Fairbrother WJ. Flygare JA, et al. Among authors: fairbrother wj. Expert Opin Ther Pat. 2010 Feb;20(2):251-67. doi: 10.1517/13543770903567077. Expert Opin Ther Pat. 2010. PMID: 20100005 Review.
Cyclodextrin Reduces Intravenous Toxicity of a Model Compound.
Mantik P, Xie M, Wong H, La H, Steigerwalt RW, Devanaboyina U, Ganem G, Shih D, Flygare JA, Fairbrother WJ, Chakravarty P, Russell D, Fernandez GE, Narang AS. Mantik P, et al. Among authors: fairbrother wj. J Pharm Sci. 2019 Jun;108(6):1934-1943. doi: 10.1016/j.xphs.2019.01.004. Epub 2019 Jan 11. J Pharm Sci. 2019. PMID: 30639736
Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling.
Goncharov T, Hedayati S, Mulvihill MM, Izrael-Tomasevic A, Zobel K, Jeet S, Fedorova AV, Eidenschenk C, deVoss J, Yu K, Shaw AS, Kirkpatrick DS, Fairbrother WJ, Deshayes K, Vucic D. Goncharov T, et al. Among authors: fairbrother wj. Mol Cell. 2018 Feb 15;69(4):551-565.e7. doi: 10.1016/j.molcel.2018.01.016. Mol Cell. 2018. PMID: 29452636 Free article.
Designer proteins to trigger cell death.
Fairbrother WJ, Ashkenazi A. Fairbrother WJ, et al. Cell. 2014 Jun 19;157(7):1506-8. doi: 10.1016/j.cell.2014.06.010. Cell. 2014. PMID: 24949963 Free article.
120 results