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2017 | 1 |
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Different FCER1A polymorphisms influence IgE levels in asthmatics and non-asthmatics.
Pediatr Allergy Immunol. 2013 Aug;24(5):441-9. doi: 10.1111/pai.12083. Epub 2013 Jun 3.
Pediatr Allergy Immunol. 2013.
PMID: 23725541
BACKGROUND: Recently, three genome-wide association studies (GWAS) demonstrated FCER1A, the gene encoding a ligand-binding subunit of the high-affinity IgE receptor, to be a major susceptibility locus for serum IgE levels. ...METHODS: Nineteen polymorphisms were stu …
BACKGROUND: Recently, three genome-wide association studies (GWAS) demonstrated FCER1A, the gene encoding a ligand-binding sub …
Association of C-Type Lectin Mincle with FcεRIβγ Subunits Leads to Functional Activation of RBL-2H3 Cells through Syk.
Honjoh C, Chihara K, Yoshiki H, Yamauchi S, Takeuchi K, Kato Y, Hida Y, Ishizuka T, Sada K.
Honjoh C, et al.
Sci Rep. 2017 Apr 10;7:46064. doi: 10.1038/srep46064.
Sci Rep. 2017.
PMID: 28393919
Free PMC article.
Macrophage-inducible C-type lectin (Mincle) interacts with the gamma-subunit of high-affinity IgE receptor (FcepsilonRIgamma) and activates Syk by recognizing its specific ligand, trehalose-6,6'-dimycolate, a glycolipid produced by Mycobacterium tuberculosis. ...
Macrophage-inducible C-type lectin (Mincle) interacts with the gamma-subunit of high-affinity IgE receptor (FcepsilonRIgamma) and activates …
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