Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2008 1
2015 1
2017 1
2020 1
2021 3
2022 1
2023 2
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

8 results

Results by year

Filters applied: . Clear all
Page 1
The CREG1-FBXO27-LAMP2 axis alleviates diabetic cardiomyopathy by promoting autophagy in cardiomyocytes.
Liu D, Xing R, Zhang Q, Tian X, Qi Y, Song H, Liu Y, Yu H, Zhang X, Jing Q, Yan C, Han Y. Liu D, et al. Exp Mol Med. 2023 Sep;55(9):2025-2038. doi: 10.1038/s12276-023-01081-2. Epub 2023 Sep 1. Exp Mol Med. 2023. PMID: 37658156 Free PMC article.
CREG1 inhibited LAMP2 protein degradation by inhibiting the protein expression of F-box protein 27 (FBXO27). Our findings indicate new roles of CREG1 in the development of diabetic cardiomyopathy....
CREG1 inhibited LAMP2 protein degradation by inhibiting the protein expression of F-box protein 27 (FBXO27). Our findings indicate ne …
TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ.
Chae CW, Yoon JH, Lim JR, Park JY, Cho JH, Jung YH, Choi GE, Lee HJ, Han HJ. Chae CW, et al. Autophagy. 2023 Oct;19(10):2752-2768. doi: 10.1080/15548627.2023.2229659. Epub 2023 Jul 4. Autophagy. 2023. PMID: 37357416
Abeta: amyloid beta; AD: Alzheimer disease; AMPK: 5' adenosine monophosphate-activated protein kinase; CTSB: cathepsin B; CTSD: cathepsin D; DM: diabetes mellitus; ESCRT: endosomal sorting complex required for transport; FBXO27: F-box protein 27; iPSC-NDs: induced pluripot …
Abeta: amyloid beta; AD: Alzheimer disease; AMPK: 5' adenosine monophosphate-activated protein kinase; CTSB: cathepsin B; CTSD: cathepsin D; …
Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles.
Yao RQ, Ren C, Xia ZF, Yao YM. Yao RQ, et al. Autophagy. 2021 Feb;17(2):385-401. doi: 10.1080/15548627.2020.1725377. Epub 2020 Feb 12. Autophagy. 2021. PMID: 32048886 Free PMC article. Review.
In this review, we summarized the recent findings and mechanisms covering different kinds of organelle-specific autophagy, as well as their involvement in various diseases, aiming to arouse concern about the significance of the quality control of multiple organelles in the treatm …
In this review, we summarized the recent findings and mechanisms covering different kinds of organelle-specific autophagy, as well as their …
Ubiquitination of exposed glycoproteins by SCF(FBXO27) directs damaged lysosomes for autophagy.
Yoshida Y, Yasuda S, Fujita T, Hamasaki M, Murakami A, Kawawaki J, Iwai K, Saeki Y, Yoshimori T, Matsuda N, Tanaka K. Yoshida Y, et al. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8574-8579. doi: 10.1073/pnas.1702615114. Epub 2017 Jul 25. Proc Natl Acad Sci U S A. 2017. PMID: 28743755 Free PMC article.
Ubiquitination functions as a signal to recruit autophagic machinery to damaged organelles and induce their clearance. Here, we report the characterization of FBXO27, a glycoprotein-specific F-box protein that is part of the SCF (SKP1/CUL1/F-box protein) ubiquitin ligase c …
Ubiquitination functions as a signal to recruit autophagic machinery to damaged organelles and induce their clearance. Here, we report the c …
Identification of candidate targets for the diagnosis and treatment of atherosclerosis by bioinformatics analysis.
Gu Y, Ma X, Li J, Ma Y, Zhang Y. Gu Y, et al. Am J Transl Res. 2021 May 15;13(5):4137-4151. eCollection 2021. Am J Transl Res. 2021. PMID: 34150004 Free PMC article.
Using DrugMatrix of the Enrichr database, we identified 16 most significant small-molecule compounds that interacted with hub genes. Finally, seven hub genes (NEDD4L, FBXO44, FBXO27, WSB1, FBXW8, UBE2F, and ASB1) in cluster 1 were considered key targets associated with ath …
Using DrugMatrix of the Enrichr database, we identified 16 most significant small-molecule compounds that interacted with hub genes. Finally …
Non-coding RNAs and related molecules associated with form-deprivation myopia in mice.
Liu S, Chen H, Ma W, Zhong Y, Liang Y, Gu L, Lu X, Li J. Liu S, et al. J Cell Mol Med. 2022 Jan;26(1):186-194. doi: 10.1111/jcmm.17071. Epub 2021 Nov 28. J Cell Mol Med. 2022. PMID: 34841657 Free PMC article.
Enrichment analysis revealed top eight transcription factors, including PAX6 and Smad3, related to myopia. Ten hub genes, including Rbx1, Fbxl3, Fbxo27, Fbxl7, Fbxo4, Cul3, Cul2, Klhl5, Fbxl16 and Klhl42, associated with ubiquitin conjugation were identified. qRT-PCR confi …
Enrichment analysis revealed top eight transcription factors, including PAX6 and Smad3, related to myopia. Ten hub genes, including Rbx1, Fb …
The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3.
Kumanomidou T, Nishio K, Takagi K, Nakagawa T, Suzuki A, Yamane T, Tokunaga F, Iwai K, Murakami A, Yoshida Y, Tanaka K, Mizushima T. Kumanomidou T, et al. PLoS One. 2015 Oct 13;10(10):e0140366. doi: 10.1371/journal.pone.0140366. eCollection 2015. PLoS One. 2015. PMID: 26460611 Free PMC article.
Among these, Fbs1/FBG1/FBXO2, Fbs2/FBG2/FBXO6, and Fbs3/FBG5/FBXO27 recognize the N-glycans of glycoproteins, whereas FBG3/FBXO44 has no sugar-binding activity, despite the high sequence homology and conservation of the residues necessary for oligosaccharide binding betwee …
Among these, Fbs1/FBG1/FBXO2, Fbs2/FBG2/FBXO6, and Fbs3/FBG5/FBXO27 recognize the N-glycans of glycoproteins, whereas FBG3/FBXO44 has …
Diversity in tissue expression, substrate binding, and SCF complex formation for a lectin family of ubiquitin ligases.
Glenn KA, Nelson RF, Wen HM, Mallinger AJ, Paulson HL. Glenn KA, et al. J Biol Chem. 2008 May 9;283(19):12717-29. doi: 10.1074/jbc.M709508200. Epub 2008 Jan 18. J Biol Chem. 2008. PMID: 18203720 Free PMC article.
The five proteins comprising this FBA family (FBXO2, FBXO6, FBXO17, FBXO27, and FBXO44) contain a conserved G domain that mediates substrate binding. ...
The five proteins comprising this FBA family (FBXO2, FBXO6, FBXO17, FBXO27, and FBXO44) contain a conserved G domain that mediates su …