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2010 1
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2020 4
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Page 1
Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists.
Zhang X, Belousoff MJ, Zhao P, Kooistra AJ, Truong TT, Ang SY, Underwood CR, Egebjerg T, Šenel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE, Danev R, Sexton PM, Wootten D. Zhang X, et al. Among authors: egebjerg t. Mol Cell. 2020 Nov 5;80(3):485-500.e7. doi: 10.1016/j.molcel.2020.09.020. Epub 2020 Oct 6. Mol Cell. 2020. PMID: 33027691 Free article.
A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice.
Østergaard H, Lund J, Greisen PJ, Kjellev S, Henriksen A, Lorenzen N, Johansson E, Røder G, Rasch MG, Johnsen LB, Egebjerg T, Lund S, Rahbek-Nielsen H, Gandhi PS, Lamberth K, Loftager M, Andersen LM, Bonde AC, Stavenuiter F, Madsen DE, Li X, Holm TL, Ley CD, Thygesen P, Zhu H, Zhou R, Thorn K, Yang Z, Hermit MB, Bjelke JR, Hansen BG, Hilden I. Østergaard H, et al. Among authors: egebjerg t. Blood. 2021 Oct 7;138(14):1258-1268. doi: 10.1182/blood.2020010331. Blood. 2021. PMID: 34077951 Free PMC article.
Nonspecificity fingerprints for clinical-stage antibodies in solution.
Herling TW, Invernizzi G, Ausserwöger H, Bjelke JR, Egebjerg T, Lund S, Lorenzen N, Knowles TPJ. Herling TW, et al. Among authors: egebjerg t. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2306700120. doi: 10.1073/pnas.2306700120. Epub 2023 Dec 18. Proc Natl Acad Sci U S A. 2023. PMID: 38109540
Design of Biopharmaceutical Formulations Accelerated by Machine Learning.
Narayanan H, Dingfelder F, Condado Morales I, Patel B, Heding KE, Bjelke JR, Egebjerg T, Butté A, Sokolov M, Lorenzen N, Arosio P. Narayanan H, et al. Among authors: egebjerg t. Mol Pharm. 2021 Oct 4;18(10):3843-3853. doi: 10.1021/acs.molpharmaceut.1c00469. Epub 2021 Sep 14. Mol Pharm. 2021. PMID: 34519511 Free article.
Surface patches induce nonspecific binding and phase separation of antibodies.
Ausserwöger H, Krainer G, Welsh TJ, Thorsteinson N, de Csilléry E, Sneideris T, Schneider MM, Egebjerg T, Invernizzi G, Herling TW, Lorenzen N, Knowles TPJ. Ausserwöger H, et al. Among authors: egebjerg t. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2210332120. doi: 10.1073/pnas.2210332120. Epub 2023 Apr 3. Proc Natl Acad Sci U S A. 2023. PMID: 37011217 Free PMC article.
SARS-CoV-2 Antibody Responses Are Correlated to Disease Severity in COVID-19 Convalescent Individuals.
Hansen CB, Jarlhelt I, Pérez-Alós L, Hummelshøj Landsy L, Loftager M, Rosbjerg A, Helgstrand C, Bjelke JR, Egebjerg T, Jardine JG, Sværke Jørgensen C, Iversen K, Bayarri-Olmos R, Garred P, Skjoedt MO. Hansen CB, et al. Among authors: egebjerg t. J Immunol. 2021 Jan 1;206(1):109-117. doi: 10.4049/jimmunol.2000898. Epub 2020 Nov 18. J Immunol. 2021. PMID: 33208457
Enhanced potency of recombinant factor VIIa with increased affinity to activated platelets.
Enoksson M, Martin EJ, Holmberg H, Jensen MS, Kjelgaard-Hansen M, Egebjerg T, Buchardt J, Krogh TN, Demuth H, Sanfridson A, Hilden I, Kjalke M, Brophy DF. Enoksson M, et al. Among authors: egebjerg t. J Thromb Haemost. 2020 Jan;18(1):104-113. doi: 10.1111/jth.14644. Epub 2019 Oct 14. J Thromb Haemost. 2020. PMID: 31549480 Free article.
Preclinical exploration of combined glucagon inhibition and liver-preferential insulin for treatment of diabetes using in vitro assays and rat and mouse models.
Hvid H, Brand CL, Hummelshøj T, Jensen S, Bouman SD, Bowler A, Poulsen BR, Tiainen P, Åkertröm T, Demozay D, Hoeg-Jensen T, Ingvorsen C, Pedersen TÅ, McGuire J, Egebjerg T, Cappelen KA, Eliasen IP, Hansen BF, Hennen S, Stidsen CE, Olsen GS, Roed NK. Hvid H, et al. Among authors: egebjerg t. Diabetologia. 2023 Feb;66(2):376-389. doi: 10.1007/s00125-022-05828-w. Epub 2022 Nov 21. Diabetologia. 2023. PMID: 36404376 Free PMC article.
Development and function of CD94-deficient natural killer cells.
Orr MT, Wu J, Fang M, Sigal LJ, Spee P, Egebjerg T, Dissen E, Fossum S, Phillips JH, Lanier LL. Orr MT, et al. Among authors: egebjerg t. PLoS One. 2010 Dec 3;5(12):e15184. doi: 10.1371/journal.pone.0015184. PLoS One. 2010. PMID: 21151939 Free PMC article.
12 results