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Clin Infect Dis. 2013 Jun;56(12):1774-7. doi: 10.1093/cid/cit124. Epub 2013 Feb 28.

Effectiveness of influenza vaccine for preventing laboratory-confirmed influenza hospitalizations in adults, 2011-2012 influenza season.

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  • 1Vanderbilt University Medical Center, Nashville, TN 37232, USA.


During the 2011-2012 influenza season, we enrolled hospitalized adults with acute respiratory illness and tested each for influenza using reverse transcription polymerase chain reaction. Influenza vaccination was verified in 35% (6/17) of adults with influenza-associated hospitalizations compared to 64% (97/152) of test-negative controls; adjusted vaccine effectiveness was 71.4% (95% confidence interval, 17.1%-94.9%).


effectiveness; influenza vaccine; older adults

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