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Page 1
Current ebola vaccines.
Hoenen T, Groseth A, Feldmann H. Hoenen T, et al. Expert Opin Biol Ther. 2012 Jul;12(7):859-72. doi: 10.1517/14712598.2012.685152. Epub 2012 May 5. Expert Opin Biol Ther. 2012. PMID: 22559078 Free PMC article. Review.
However, a number of vaccine candidates have been developed in the last decade that are highly protective in NHPs, the gold standard animal model for ebola hemorrhagic fever. AREAS COVERED: This review analyzes a number of scenarios for the use of ebolavirus vaccines
However, a number of vaccine candidates have been developed in the last decade that are highly protective in NHPs, the gold standard animal …
Ebola vaccines in clinical trial: The promising candidates.
Wang Y, Li J, Hu Y, Liang Q, Wei M, Zhu F. Wang Y, et al. Hum Vaccin Immunother. 2017 Jan 2;13(1):153-168. doi: 10.1080/21645515.2016.1225637. Epub 2016 Oct 20. Hum Vaccin Immunother. 2017. PMID: 27764560 Free PMC article. Review.
Ebola virus disease (EVD) has become a great threat to humans across the world in recent years. ...We retrospectively reviewed the current development of Ebola vaccines and discussed issues and challenges remaining to be investigated in the future....
Ebola virus disease (EVD) has become a great threat to humans across the world in recent years. ...We retrospectively reviewed the cu
Ebola Virus Disease: Epidemiology, Clinical Features, Management, and Prevention.
Nicastri E, Kobinger G, Vairo F, Montaldo C, Mboera LEG, Ansunama R, Zumla A, Ippolito G. Nicastri E, et al. Infect Dis Clin North Am. 2019 Dec;33(4):953-976. doi: 10.1016/j.idc.2019.08.005. Infect Dis Clin North Am. 2019. PMID: 31668200 Review.
Ebola virus disease (EVD) is a deadly zoonotic disease caused by the Ebola virus. ...The emerging diagnostic technologies, rapid viral characterization, geospatial mapping of EVD transmission, and new treatments and vaccines are discussed....
Ebola virus disease (EVD) is a deadly zoonotic disease caused by the Ebola virus. ...The emerging diagnostic technologies, rap
Ebola Virus: Pathogenesis and Countermeasure Development.
Furuyama W, Marzi A. Furuyama W, et al. Annu Rev Virol. 2019 Sep 29;6(1):435-458. doi: 10.1146/annurev-virology-092818-015708. Annu Rev Virol. 2019. PMID: 31567063 Review.
Since its discovery in 1976, Ebola virus (EBOV) has caused numerous outbreaks of fatal hemorrhagic disease in Africa. ...In the same manner, vaccines with preclinical efficacy were administered primarily to known contacts of EVD patients on clinical trial protocols …
Since its discovery in 1976, Ebola virus (EBOV) has caused numerous outbreaks of fatal hemorrhagic disease in Africa. ...In the same …
Can Ebola Virus Vaccines Have Universal Immune Correlates of protection?
Meyer M, Malherbe DC, Bukreyev A. Meyer M, et al. Trends Microbiol. 2019 Jan;27(1):8-16. doi: 10.1016/j.tim.2018.08.008. Epub 2018 Sep 7. Trends Microbiol. 2019. PMID: 30201511 Free PMC article. Review.
Testing vaccine efficacy against the highly lethal Ebola virus (EBOV) in humans is almost impossible due to obvious ethical reasons and the sporadic nature of outbreaks. ...In the hope of identifying a reliable correlate by comparing preclinical and clinical trial data on …
Testing vaccine efficacy against the highly lethal Ebola virus (EBOV) in humans is almost impossible due to obvious ethical reasons a …
Ebola virus disease: current vaccine solutions.
Tomori O, Kolawole MO. Tomori O, et al. Curr Opin Immunol. 2021 Aug;71:27-33. doi: 10.1016/j.coi.2021.03.008. Epub 2021 Apr 17. Curr Opin Immunol. 2021. PMID: 33873076 Review.
Ebola Virus Disease (EVD) is an emerging zoonotic disease with intermittent outbreaks in Central and West African countries. ...The licensing of an Ebola vaccine for use is challenging for several reasons, including the sporadic and limited nature of EVD outbreaks a
Ebola Virus Disease (EVD) is an emerging zoonotic disease with intermittent outbreaks in Central and West African countries. ...The l
Recent developments and strategies of Ebola virus vaccines.
Sharma AR, Lee YH, Nath S, Lee SS. Sharma AR, et al. Curr Opin Pharmacol. 2021 Oct;60:46-53. doi: 10.1016/j.coph.2021.06.008. Epub 2021 Jul 27. Curr Opin Pharmacol. 2021. PMID: 34329960 Review.
The Filovirus family member, Ebola virus (EBOV), is a highly infectious pathogen responsible for viral hemorrhagic fever. ...Fortunately, owing to continuous efforts and several vaccine platforms, few potential vaccine candidates are emerging, such as replicative and non-r …
The Filovirus family member, Ebola virus (EBOV), is a highly infectious pathogen responsible for viral hemorrhagic fever. ...Fortunat …
Ebola virus disease candidate vaccines under evaluation in clinical trials.
Martins KA, Jahrling PB, Bavari S, Kuhn JH. Martins KA, et al. Expert Rev Vaccines. 2016 Sep;15(9):1101-12. doi: 10.1080/14760584.2016.1187566. Epub 2016 May 27. Expert Rev Vaccines. 2016. PMID: 27160784 Free PMC article. Review.
Filoviruses are the etiological agents of two human illnesses: Ebola virus disease and Marburg virus disease. Until 2013, medical countermeasure development against these afflictions was limited to only a few research institutes worldwide as both infections were considered …
Filoviruses are the etiological agents of two human illnesses: Ebola virus disease and Marburg virus disease. Until 2013, medical cou …
Randomized Trial of Vaccines for Zaire Ebola Virus Disease.
PREVAC Study Team; Kieh M, Richert L, Beavogui AH, Grund B, Leigh B, D'Ortenzio E, Doumbia S, Lhomme E, Sow S, Vatrinet R, Roy C, Kennedy SB, Faye S, Lees S, Millimouno NP, Camara AM, Samai M, Deen GF, Doumbia M, Espérou H, Pierson J, Watson-Jones D, Diallo A, Wentworth D, McLean C, Simon J, Wiedemann A, Dighero-Kemp B, Hensley L, Lane HC, Levy Y, Piot P, Greenwood B, Chêne G, Neaton J, Yazdanpanah Y. PREVAC Study Team, et al. N Engl J Med. 2022 Dec 29;387(26):2411-2424. doi: 10.1056/NEJMoa2200072. Epub 2022 Dec 14. N Engl J Med. 2022. PMID: 36516078 Clinical Trial.
BACKGROUND: Questions remain concerning the rapidity of immune responses and the durability and safety of vaccines used to prevent Zaire Ebola virus disease. METHODS: We conducted two randomized, placebo-controlled trials - one involving adults and one involving chi …
BACKGROUND: Questions remain concerning the rapidity of immune responses and the durability and safety of vaccines used to prevent Za …
Development of vaccines for prevention of Ebola virus infection.
Ye L, Yang C. Ye L, et al. Microbes Infect. 2015 Feb;17(2):98-108. doi: 10.1016/j.micinf.2014.12.004. Epub 2014 Dec 16. Microbes Infect. 2015. PMID: 25526819 Free article. Review.
While licensed vaccines against Ebola virus infection are still not available, a number of vaccine approaches have been developed and shown to protect against lethal Ebola virus infection in animal models. ...In addition, the development of animal models for …
While licensed vaccines against Ebola virus infection are still not available, a number of vaccine approaches have been develo …
1,900 results