Dreyer MK[Author] - Search Results

Year	Number of Results
1993	1
1996	2
2000	1
2001	3
2002	1
2004	1
2008	1
2010	2
2013	1
2017	1
2018	3
2019	1
2021	1
2022	1
2024	0

1

The signalling conformation of the insulin receptor ectodomain.

Weis F, Menting JG, Margetts MB, Chan SJ, Xu Y, Tennagels N, Wohlfart P, Langer T, Müller CW, Dreyer MK, Lawrence MC. Weis F, et al. Among authors: dreyer mk. Nat Commun. 2018 Oct 24;9(1):4420. doi: 10.1038/s41467-018-06826-6. Nat Commun. 2018. PMID: 30356040 Free PMC article.

2

The crystal structure of the BMP-2:BMPR-IA complex and the generation of BMP-2 antagonists.

Nickel J, Dreyer MK, Kirsch T, Sebald W. Nickel J, et al. Among authors: dreyer mk. J Bone Joint Surg Am. 2001;83-A Suppl 1(Pt 1):S7-14. J Bone Joint Surg Am. 2001. PMID: 11263668 Review.

3

Estimation of Protein-Ligand Unbinding Kinetics Using Non-Equilibrium Targeted Molecular Dynamics Simulations.

Wolf S, Amaral M, Lowinski M, Vallée F, Musil D, Güldenhaupt J, Dreyer MK, Bomke J, Frech M, Schlitter J, Gerwert K. Wolf S, et al. Among authors: dreyer mk. J Chem Inf Model. 2019 Dec 23;59(12):5135-5147. doi: 10.1021/acs.jcim.9b00592. Epub 2019 Nov 22. J Chem Inf Model. 2019. PMID: 31697501

4

Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis.

Halland N, Schmidt F, Weiss T, Li Z, Czech J, Saas J, Ding-Pfennigdorff D, Dreyer MK, Strübing C, Nazare M. Halland N, et al. Among authors: dreyer mk. J Med Chem. 2022 Jan 27;65(2):1567-1584. doi: 10.1021/acs.jmedchem.1c01601. Epub 2021 Dec 21. J Med Chem. 2022. PMID: 34931844

5

Estimation of Drug-Target Residence Times by τ-Random Acceleration Molecular Dynamics Simulations.

Kokh DB, Amaral M, Bomke J, Grädler U, Musil D, Buchstaller HP, Dreyer MK, Frech M, Lowinski M, Vallee F, Bianciotto M, Rak A, Wade RC. Kokh DB, et al. Among authors: dreyer mk. J Chem Theory Comput. 2018 Jul 10;14(7):3859-3869. doi: 10.1021/acs.jctc.8b00230. Epub 2018 Jun 4. J Chem Theory Comput. 2018. PMID: 29768913 Free article.

6

Crystal structure of the BMP-2-BRIA ectodomain complex.

Kirsch T, Sebald W, Dreyer MK. Kirsch T, et al. Among authors: dreyer mk. Nat Struct Biol. 2000 Jun;7(6):492-6. doi: 10.1038/75903. Nat Struct Biol. 2000. PMID: 10881198

7

Accounting for conformational variability in protein-ligand docking with NMR-guided rescoring.

Skjærven L, Codutti L, Angelini A, Grimaldi M, Latek D, Monecke P, Dreyer MK, Carlomagno T. Skjærven L, et al. Among authors: dreyer mk. J Am Chem Soc. 2013 Apr 17;135(15):5819-27. doi: 10.1021/ja4007468. Epub 2013 Apr 8. J Am Chem Soc. 2013. PMID: 23565800

8

Kinetics of human cannabinoid 1 (CB1) receptor antagonists: Structure-kinetics relationships (SKR) and implications for insurmountable antagonism.

Xia L, de Vries H, Yang X, Lenselink EB, Kyrizaki A, Barth F, Louvel J, Dreyer MK, van der Es D, IJzerman AP, Heitman LH. Xia L, et al. Among authors: dreyer mk. Biochem Pharmacol. 2018 May;151:166-179. doi: 10.1016/j.bcp.2017.10.014. Epub 2017 Nov 2. Biochem Pharmacol. 2018. PMID: 29102677 Free article.

9

Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors.

Anderka O, Loenze P, Klabunde T, Dreyer MK, Defossa E, Wendt KU, Schmoll D. Anderka O, et al. Among authors: dreyer mk. Biochemistry. 2008 Apr 22;47(16):4683-91. doi: 10.1021/bi702397d. Epub 2008 Mar 29. Biochemistry. 2008. PMID: 18373353

10

Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2.

Lesuisse D, Dutruc-Rosset G, Tiraboschi G, Dreyer MK, Maignan S, Chevalier A, Halley F, Bertrand P, Burgevin MC, Quarteronet D, Rooney T. Lesuisse D, et al. Among authors: dreyer mk. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1985-9. doi: 10.1016/j.bmcl.2010.01.114. Epub 2010 Jan 25. Bioorg Med Chem Lett. 2010. PMID: 20167481

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