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Mannose receptor induces T-cell tolerance via inhibition of CD45 and up-regulation of CTLA-4.
Schuette V, Embgenbroich M, Ulas T, Welz M, Schulte-Schrepping J, Draffehn AM, Quast T, Koch K, Nehring M, König J, Zweynert A, Harms FL, Steiner N, Limmer A, Förster I, Berberich-Siebelt F, Knolle PA, Wohlleber D, Kolanus W, Beyer M, Schultze JL, Burgdorf S. Schuette V, et al. Among authors: draffehn am. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):10649-54. doi: 10.1073/pnas.1605885113. Epub 2016 Sep 6. Proc Natl Acad Sci U S A. 2016. PMID: 27601670 Free PMC article.
The Connexin40A96S mutation from a patient with atrial fibrillation causes decreased atrial conduction velocities and sustained episodes of induced atrial fibrillation in mice.
Lübkemeier I, Andrié R, Lickfett L, Bosen F, Stöckigt F, Dobrowolski R, Draffehn AM, Fregeac J, Schultze JL, Bukauskas FF, Schrickel JW, Willecke K. Lübkemeier I, et al. Among authors: draffehn am. J Mol Cell Cardiol. 2013 Dec;65:19-32. doi: 10.1016/j.yjmcc.2013.09.008. Epub 2013 Sep 21. J Mol Cell Cardiol. 2013. PMID: 24060583