Abstract
We investigated the prevalence of xenotropic murine leukemia virus-related virus (XMRV) among 293 participants seen at academic hospitals in Boston, Massachusetts. Participants were recruited from the following 5 groups of patients: chronic fatigue syndrome (n = 32), human immunodeficiency virus infection (n = 43), rheumatoid arthritis (n = 97), hematopoietic stem-cell or solid organ transplant (n = 26), or a general cohort of patients presenting for medical care (n = 95). XMRV DNA was not detected in any participant samples. We found no association between XMRV and patients with chronic fatigue syndrome or chronic immunomodulatory conditions.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Arthritis, Rheumatoid / immunology
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Arthritis, Rheumatoid / virology
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Cohort Studies
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Cross-Sectional Studies
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DNA, Viral / genetics
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Fatigue Syndrome, Chronic / epidemiology
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Fatigue Syndrome, Chronic / virology*
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Female
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HIV Infections / immunology
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HIV Infections / virology
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Hematopoietic Stem Cell Transplantation
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Humans
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Immunocompromised Host*
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Leukemia Virus, Murine / genetics
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Leukemia Virus, Murine / isolation & purification*
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Male
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Massachusetts / epidemiology
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Middle Aged
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Organ Transplantation
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Polymerase Chain Reaction
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Retroviridae Infections / epidemiology*
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Transplantation Immunology
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Tumor Virus Infections / epidemiology*