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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1984 4
1990 3
1991 1
1994 5
1995 2
1996 2
1997 2
1998 2
1999 4
2000 12
2001 10
2002 14
2003 10
2004 8
2005 15
2006 13
2007 6
2008 12
2009 13
2010 13
2011 10
2012 13
2013 10
2014 9
2015 8
2016 10
2017 8
2018 6
2019 8
2020 4
2021 5
2022 10
2023 4
2024 1

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242 results

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Page 1
Malaria: Biology and Disease.
Cowman AF, Healer J, Marapana D, Marsh K. Cowman AF, et al. Cell. 2016 Oct 20;167(3):610-624. doi: 10.1016/j.cell.2016.07.055. Cell. 2016. PMID: 27768886 Free article. Review.
Malaria has been a major global health problem of humans through history and is a leading cause of death and disease across many tropical and subtropical countries. Over the last fifteen years renewed efforts at control have reduced the prevalence of malaria by over …
Malaria has been a major global health problem of humans through history and is a leading cause of death and disease across many trop …
Vaccines to Accelerate Malaria Elimination and Eventual Eradication.
Healer J, Cowman AF, Kaslow DC, Birkett AJ. Healer J, et al. Among authors: cowman af. Cold Spring Harb Perspect Med. 2017 Sep 1;7(9):a025627. doi: 10.1101/cshperspect.a025627. Cold Spring Harb Perspect Med. 2017. PMID: 28490535 Free PMC article. Review.
Remarkable progress has been made in coordinated malaria control efforts with substantial reductions in malaria-associated deaths and morbidity achieved through mass administration of drugs and vector control measures including distribution of long-lasting insectici …
Remarkable progress has been made in coordinated malaria control efforts with substantial reductions in malaria-associated dea …
Plasmepsin X activates the PCRCR complex of Plasmodium falciparum by processing PfRh5 for erythrocyte invasion.
Triglia T, Scally SW, Seager BA, Pasternak M, Dagley LF, Cowman AF. Triglia T, et al. Among authors: cowman af. Nat Commun. 2023 Apr 19;14(1):2219. doi: 10.1038/s41467-023-37890-2. Nat Commun. 2023. PMID: 37072430 Free PMC article.
Plasmodium falciparum causes the most severe form of malaria in humans. The protozoan parasite develops within erythrocytes to mature schizonts, that contain more than 16 merozoites, which egress and invade fresh erythrocytes. ...
Plasmodium falciparum causes the most severe form of malaria in humans. The protozoan parasite develops within erythrocytes to mature …
Chemotherapy and drug resistance in malaria.
Cowman AF, Foote SJ. Cowman AF, et al. Int J Parasitol. 1990 Jul;20(4):503-13. doi: 10.1016/0020-7519(90)90198-v. Int J Parasitol. 1990. PMID: 2210944 Review.
Over recent years many antimalarial drugs have been rendered useless by the development of resistance by the malaria parasite. New antimalarials are rapidly suffering the same fate as the traditional therapies and yet a biological understanding of the mechanisms of resista …
Over recent years many antimalarial drugs have been rendered useless by the development of resistance by the malaria parasite. New an …
Chemo-proteomics in antimalarial target identification and engagement.
Bailey BL, Nguyen W, Cowman AF, Sleebs BE. Bailey BL, et al. Among authors: cowman af. Med Res Rev. 2023 Nov;43(6):2303-2351. doi: 10.1002/med.21975. Epub 2023 May 26. Med Res Rev. 2023. PMID: 37232495 Free PMC article. Review.
Humans have lived in tenuous battle with malaria over millennia. Today, while much of the world is free of the disease, areas of South America, Asia, and Africa still wage this war with substantial impacts on their social and economic development. ...
Humans have lived in tenuous battle with malaria over millennia. Today, while much of the world is free of the disease, areas of Sout …
Molecular profiling reveals features of clinical immunity and immunosuppression in asymptomatic P. falciparum malaria.
Studniberg SI, Ioannidis LJ, Utami RAS, Trianty L, Liao Y, Abeysekera W, Li-Wai-Suen CSN, Pietrzak HM, Healer J, Puspitasari AM, Apriyanti D, Coutrier F, Poespoprodjo JR, Kenangalem E, Andries B, Prayoga P, Sariyanti N, Smyth GK, Cowman AF, Price RN, Noviyanti R, Shi W, Garnham AL, Hansen DS. Studniberg SI, et al. Among authors: cowman af. Mol Syst Biol. 2022 Apr;18(4):e10824. doi: 10.15252/msb.202110824. Mol Syst Biol. 2022. PMID: 35475529 Free PMC article.
Clinical immunity to P. falciparum malaria is non-sterilizing, with adults often experiencing asymptomatic infection. Historically, asymptomatic malaria has been viewed as beneficial and required to help maintain clinical immunity. ...
Clinical immunity to P. falciparum malaria is non-sterilizing, with adults often experiencing asymptomatic infection. Historically, a …
Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine.
Webster R, Sekuloski S, Odedra A, Woolley S, Jennings H, Amante F, Trenholme KR, Healer J, Cowman AF, Eriksson EM, Sathe P, Penington J, Blanch AJ, Dixon MWA, Tilley L, Duffy MF, Craig A, Storm J, Chan JA, Evans K, Papenfuss AT, Schofield L, Griffin P, Barber BE, Andrew D, Boyle MJ, de Labastida Rivera F, Engwerda C, McCarthy JS. Webster R, et al. Among authors: cowman af. BMC Med. 2021 Nov 22;19(1):293. doi: 10.1186/s12916-021-02150-x. BMC Med. 2021. PMID: 34802442 Free PMC article. Clinical Trial.
BACKGROUND: There is a clear need for novel approaches to malaria vaccine development. We aimed to develop a genetically attenuated blood-stage vaccine and test its safety, infectivity, and immunogenicity in healthy volunteers. ...CONCLUSIONS: This study represents the fir …
BACKGROUND: There is a clear need for novel approaches to malaria vaccine development. We aimed to develop a genetically attenuated b …
PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum.
Scally SW, Triglia T, Evelyn C, Seager BA, Pasternak M, Lim PS, Healer J, Geoghegan ND, Adair A, Tham WH, Dagley LF, Rogers KL, Cowman AF. Scally SW, et al. Among authors: cowman af. Nat Microbiol. 2022 Dec;7(12):2039-2053. doi: 10.1038/s41564-022-01261-2. Epub 2022 Nov 17. Nat Microbiol. 2022. PMID: 36396942 Free PMC article.
The most severe form of malaria is caused by Plasmodium falciparum. These parasites invade human erythrocytes, and an essential step in this process involves the ligand PfRh5, which forms a complex with cysteine-rich protective antigen (CyRPA) and PfRh5-interacting protein …
The most severe form of malaria is caused by Plasmodium falciparum. These parasites invade human erythrocytes, and an essential step …
The cellular and molecular basis for malaria parasite invasion of the human red blood cell.
Cowman AF, Berry D, Baum J. Cowman AF, et al. J Cell Biol. 2012 Sep 17;198(6):961-71. doi: 10.1083/jcb.201206112. J Cell Biol. 2012. PMID: 22986493 Free PMC article. Review.
Malaria is a major disease of humans caused by protozoan parasites from the genus Plasmodium. ...
Malaria is a major disease of humans caused by protozoan parasites from the genus Plasmodium. ...
Identification and prioritization of merozoite antigens as targets of protective human immunity to Plasmodium falciparum malaria for vaccine and biomarker development.
Richards JS, Arumugam TU, Reiling L, Healer J, Hodder AN, Fowkes FJ, Cross N, Langer C, Takeo S, Uboldi AD, Thompson JK, Gilson PR, Coppel RL, Siba PM, King CL, Torii M, Chitnis CE, Narum DL, Mueller I, Crabb BS, Cowman AF, Tsuboi T, Beeson JG. Richards JS, et al. Among authors: cowman af. J Immunol. 2013 Jul 15;191(2):795-809. doi: 10.4049/jimmunol.1300778. Epub 2013 Jun 17. J Immunol. 2013. PMID: 23776179 Free PMC article.
The development of effective malaria vaccines and immune biomarkers of malaria is a high priority for malaria control and elimination. ...This study identifies Ags that are likely to be key targets of protective human immunity and facilitates the prioritizati …
The development of effective malaria vaccines and immune biomarkers of malaria is a high priority for malaria control a …
242 results