Chronic myelogenous leukemia: from molecular biology to clinical aspects and novel targeted therapies.
J Nippon Med Sch. 2006.
PMID: 16936444
Review.
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Chronic myelogenous leukemia: from molecular biology to clinical aspects and novel targeted therapies.
Inokuchi K.
Inokuchi K.
J Nippon Med Sch. 2006 Aug;73(4):178-92. doi: 10.1272/jnms.73.178.
J Nippon Med Sch. 2006.
PMID: 16936444
Free article.
Review.
The critical causative event in chronic myelogenous leukemia (CML) is the fusion of the head of the bcr gene with the body of the abl gene, named bcr/abl gene. ...This article reviews the history of BCR/ABL molecular biol …
The critical causative event in chronic myelogenous leukemia (CML) is the fusion of the head of the bcr gene with the b …
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Advances in understanding and management of polycythemia vera.
Vannucchi AM, Guglielmelli P.
Vannucchi AM, et al.
Curr Opin Oncol. 2010 Nov;22(6):636-41. doi: 10.1097/CCO.0b013e32833ed81c.
Curr Opin Oncol. 2010.
PMID: 20805747
Review.
However, the expectation that these drugs could selectively target mutant cells and cause a molecular remission, similar to the experience with imatinib in chronic myelogenous leukemia, has been largely unmet. ...SUMMARY: The last couple of year …
However, the expectation that these drugs could selectively target mutant cells and cause a molecular remission, similar to th …
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Targeting tumor micro-environment for design and development of novel anti-angiogenic agents arresting tumor growth.
Gacche RN, Meshram RJ.
Gacche RN, et al.
Prog Biophys Mol Biol. 2013 Nov;113(2):333-54. doi: 10.1016/j.pbiomolbio.2013.10.001. Epub 2013 Oct 15.
Prog Biophys Mol Biol. 2013.
PMID: 24139944
Review.
Couple of decade's research in molecular aspects of tumor biology has unraveled numerous structural and functional mysteries of these angiogenic peptides. ...We also discuss major therapeutic agents that are currently used in angiogenesis associated therap …
Couple of decade's research in molecular aspects of tumor biology has unraveled numerous structural and functional myst …
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