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1993 1
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218 results

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Page 1
CYCS gene variants associated with thrombocytopenia.
Ledgerwood EC, Dunstan-Harrison C, Ong L, Morison IM. Ledgerwood EC, et al. Platelets. 2019;30(5):672-674. doi: 10.1080/09537104.2018.1543866. Epub 2018 Nov 19. Platelets. 2019. PMID: 30452302 No abstract available.
The role of STAT3 in autophagy.
You L, Wang Z, Li H, Shou J, Jing Z, Xie J, Sui X, Pan H, Han W. You L, et al. Autophagy. 2015;11(5):729-39. doi: 10.1080/15548627.2015.1017192. Autophagy. 2015. PMID: 25951043 Free PMC article. Review.
The multifaceted regulation of mitophagy by endogenous metabolites.
Zhang T, Liu Q, Gao W, Sehgal SA, Wu H. Zhang T, et al. Autophagy. 2022 Jun;18(6):1216-1239. doi: 10.1080/15548627.2021.1975914. Epub 2021 Sep 29. Autophagy. 2022. PMID: 34583624 Free PMC article.
We also highlight the key regulations of mammalian mitophagy by endogenous metabolites, shed new light on the bidirectional interplay between mitophagy and cellular metabolisms, with attempting to provide a perspective insight into the nutritional intervention of metabolic disord …
We also highlight the key regulations of mammalian mitophagy by endogenous metabolites, shed new light on the bidirectional interplay betwee …
[Role of CYCS in the cytogenesis and apoptosis of male germ cells and its clinical application].
Liang YD, Zhao K, Chen Y, Zhang SQ. Liang YD, et al. Zhonghua Nan Ke Xue. 2020 Mar;26(3):265-270. Zhonghua Nan Ke Xue. 2020. PMID: 33346968 Review. Chinese.
As a key factor of cell apoptosis in the mitochondrial pathway, cytochrome c, somatic (CYCS) plays an important role in the process of male spermatogenesis. Based on more than 40 recent studies on CYCS by Chinese and foreign scholars, this review focuses on the invo …
As a key factor of cell apoptosis in the mitochondrial pathway, cytochrome c, somatic (CYCS) plays an important role in the process o …
Copper metabolism in cell death and autophagy.
Xue Q, Kang R, Klionsky DJ, Tang D, Liu J, Chen X. Xue Q, et al. Autophagy. 2023 Aug;19(8):2175-2195. doi: 10.1080/15548627.2023.2200554. Epub 2023 Apr 16. Autophagy. 2023. PMID: 37055935 Free PMC article. Review.
This knowledge may help in the design of future clinical tools to improve cancer diagnosis and treatment.Abbreviations: ACSL4, acyl-CoA synthetase long chain family member 4; AIFM1/AIF, apoptosis inducing factor mitochondria associated 1; AIFM2, apoptosis inducing factor mitochon …
This knowledge may help in the design of future clinical tools to improve cancer diagnosis and treatment.Abbreviations: ACSL4, acyl-CoA synt …
Mitophagy regulates mitochondrial network signaling, oxidative stress, and apoptosis during myoblast differentiation.
Baechler BL, Bloemberg D, Quadrilatero J. Baechler BL, et al. Autophagy. 2019 Sep;15(9):1606-1619. doi: 10.1080/15548627.2019.1591672. Epub 2019 Apr 7. Autophagy. 2019. PMID: 30859901 Free PMC article.
., PPARGC1A, DNM1L, OPA1) and protein content (e.g., SLC25A4, VDAC1, CYCS). Moreover, shAtg7 myoblasts displayed CYCS and AIFM1 release from mitochondria, and CASP9 activation. ...Abbreviations: 3MA: 3-methyladenine; 4-HNE: 4-hydroxynonenal; ACT: actin; AIFM1/AIF: a …
., PPARGC1A, DNM1L, OPA1) and protein content (e.g., SLC25A4, VDAC1, CYCS). Moreover, shAtg7 myoblasts displayed CYCS and AIFM …
The role of mitophagy in the regulation of mitochondrial energetic status in neurons.
Han S, Zhang M, Jeong YY, Margolis DJ, Cai Q. Han S, et al. Autophagy. 2021 Dec;17(12):4182-4201. doi: 10.1080/15548627.2021.1907167. Epub 2021 Apr 5. Autophagy. 2021. PMID: 33757395 Free PMC article.
Taken together, we propose a new mechanism by which mitophagy controls bioenergetic status in neurons, furthering our understanding of the direct impact of mitophagy defects on AD-linked metabolic deficits and shedding light on the development of novel therapeutic strategies to t …
Taken together, we propose a new mechanism by which mitophagy controls bioenergetic status in neurons, furthering our understanding of the d …
WIPI2 positively regulates mitophagy by promoting mitochondrial recruitment of VCP.
Lu G, Tan HWS, Schmauck-Medina T, Wang L, Chen J, Cho YL, Chen K, Zhang JZ, He W, Wu Y, Xia D, Zhou J, Fang EF, Fang L, Liu W, Shen HM. Lu G, et al. Autophagy. 2022 Dec;18(12):2865-2879. doi: 10.1080/15548627.2022.2052461. Epub 2022 Apr 7. Autophagy. 2022. PMID: 35389758 Free PMC article.
In summary, our study reveals a critical regulatory role of WIPI2 in mitochondrial recruitment of VCP to promote OMM protein degradation and eventual mitophagy.Abbreviations: ATG, autophagy related; CALCOCO2/NDP52, calcium binding and coiled-coil domain 2; CCCP, carbonyl cyanide …
In summary, our study reveals a critical regulatory role of WIPI2 in mitochondrial recruitment of VCP to promote OMM protein degradation and …
SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence.
Salazar G, Cullen A, Huang J, Zhao Y, Serino A, Hilenski L, Patrushev N, Forouzandeh F, Hwang HS. Salazar G, et al. Autophagy. 2020 Jun;16(6):1092-1110. doi: 10.1080/15548627.2019.1659612. Epub 2019 Aug 28. Autophagy. 2020. PMID: 31441382 Free PMC article.
ABBREVIATIONS: 3-MA: 3 methyladenine; ACTA2/SM-actin: actin, alpha 2, smooth muscle, aorta; ACTB/beta-actin: actin beta; AGT II: angiotensin II; ATG5: autophagy related 5; BECN1: beclin 1; CAT: catalase; CDKN1A: cyclin-dependent kinase inhibitor 1A (P21); Chl: chloroquine; CTSD: …
ABBREVIATIONS: 3-MA: 3 methyladenine; ACTA2/SM-actin: actin, alpha 2, smooth muscle, aorta; ACTB/beta-actin: actin beta; AGT II: angiotensin …
Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations.
Li H, Ham A, Ma TC, Kuo SH, Kanter E, Kim D, Ko HS, Quan Y, Sardi SP, Li A, Arancio O, Kang UJ, Sulzer D, Tang G. Li H, et al. Autophagy. 2019 Jan;15(1):113-130. doi: 10.1080/15548627.2018.1509818. Epub 2018 Oct 12. Autophagy. 2019. PMID: 30160596 Free PMC article.
Abbreviations: AMBRA1: autophagy/beclin 1 regulator 1; BECN1: beclin 1, autophagy related; BNIP3L/Nix: BCL2/adenovirus E1B interacting protein 3-like; CCCP: carbonyl cyanide 3-chloroyphenylhydrazone; CYCS: cytochrome c, somatic; DNM1L/DRP1: dynamin 1-like; ER: endoplasmic …
Abbreviations: AMBRA1: autophagy/beclin 1 regulator 1; BECN1: beclin 1, autophagy related; BNIP3L/Nix: BCL2/adenovirus E1B interacting prote …
218 results