Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 2
2008 1
2009 4
2010 2
2011 2
2012 6
2013 7
2014 2
2015 6
2016 8
2017 10
2018 9
2019 12
2020 10
2021 9
2022 10
2023 17
2024 5

Text availability

Article attribute

Article type

Publication date

Search Results

106 results

Results by year

Filters applied: . Clear all
Page 1
CXXC5: A novel regulator and coordinator of TGF-beta, BMP and Wnt signaling.
Xiong X, Tu S, Wang J, Luo S, Yan X. Xiong X, et al. J Cell Mol Med. 2019 Feb;23(2):740-749. doi: 10.1111/jcmm.14046. Epub 2018 Nov 27. J Cell Mol Med. 2019. PMID: 30479059 Free PMC article. Review.
Intriguingly, increasing evidence indicates that expression of the CXXC5 gene is controlled by multiple signaling pathways and a variety of transcription factors, positioning CXXC5 as an important signal integrator. ...This review summarizes the current understandin …
Intriguingly, increasing evidence indicates that expression of the CXXC5 gene is controlled by multiple signaling pathways and a vari …
CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD(2).
Ryu YC, Park J, Kim YR, Choi S, Kim GU, Kim E, Hwang Y, Kim H, Han G, Lee SH, Choi KY. Ryu YC, et al. Cells. 2023 Feb 9;12(4):555. doi: 10.3390/cells12040555. Cells. 2023. PMID: 36831222 Free PMC article.
The hair loss by PGD(2) was restored by Cxxc5 knock-out or treatment of protein transduction domain-Dishevelled binding motif (PTD-DBM), a peptide activating the Wnt/beta-catenin pathway via interference with the Dishevelled (Dvl) binding function of CXXC5. ...Moreo …
The hair loss by PGD(2) was restored by Cxxc5 knock-out or treatment of protein transduction domain-Dishevelled binding motif (PTD-DB …
CXXC5: A novel regulator of myelopoiesis.
Capitano ML. Capitano ML. J Leukoc Biol. 2020 Aug;108(2):451-453. doi: 10.1002/JLB.1CE0420-106R. J Leukoc Biol. 2020. PMID: 32745327
Discussion on how CXXC5 alters hematopoiesis by regulating the differentiation of hematopoietic stem and progenitor cells toward monocyte development....
Discussion on how CXXC5 alters hematopoiesis by regulating the differentiation of hematopoietic stem and progenitor cells toward mono …
Inhibition of CXXC5 function reverses obesity-related metabolic diseases.
Seo SH, Kim E, Lee SH, Lee YH, Han DH, Go H, Seong JK, Choi KY. Seo SH, et al. Clin Transl Med. 2022 Apr;12(4):e742. doi: 10.1002/ctm2.742. Clin Transl Med. 2022. PMID: 35384342 Free PMC article.
HFD-fed mice treated with KY19334, a small molecule inhibiting CXXC5-Dvl protein-protein interaction (PPI), was used to assess the role of CXXC5 in metabolic diseases. ...Meanwhile, Cxxc5(-/-) mice fed an HFD exhibited resistance to metabolic dysregulation. . …
HFD-fed mice treated with KY19334, a small molecule inhibiting CXXC5-Dvl protein-protein interaction (PPI), was used to assess the ro …
CXXC5 orchestrates Stat3/Erk/Akt signaling networks to modulate P. gingivalis-elicited autophagy in cementoblasts.
Ma L, Liu H, Wang X, Jiang C, Yao S, Guo Y, Wang H, Cao Z. Ma L, et al. Biochim Biophys Acta Mol Cell Res. 2021 Mar;1868(3):118923. doi: 10.1016/j.bbamcr.2020.118923. Epub 2020 Dec 5. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 33285176 Free article.
After coculture with P. gingivalis, cementoblasts exhibited inflammatory cytokine increase, light chain 3(LC3)-I/II conversion, autophagosome activation, and CXXC5 reduction. Cementoblasts with loss and gain of CXXC5 were developed. CXXC5 silencing suppressed …
After coculture with P. gingivalis, cementoblasts exhibited inflammatory cytokine increase, light chain 3(LC3)-I/II conversion, autophagosom …
CXXC5 mitigates P. gingivalis-inhibited cementogenesis by influencing mitochondrial biogenesis.
Ma L, Wang H, Huang X, Huang H, Peng Y, Liu H, Wang X, Cao Z. Ma L, et al. Cell Commun Signal. 2024 Jan 2;22(1):4. doi: 10.1186/s12964-023-01283-1. Cell Commun Signal. 2024. PMID: 38167023 Free PMC article.
We have previously proved transcription factor CXXC-type zinc finger protein 5 (CXXC5) participates in cementogenesis. Here, we aimed to elucidate the mechanism in which CXXC5 regulates P. gingivalis-inhibited cementogenesis from the perspective of mitochondrial bio …
We have previously proved transcription factor CXXC-type zinc finger protein 5 (CXXC5) participates in cementogenesis. Here, we aimed …
Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis.
Lee SH, Seo SH, Lee DH, Pi LQ, Lee WS, Choi KY. Lee SH, et al. J Invest Dermatol. 2017 Nov;137(11):2260-2269. doi: 10.1016/j.jid.2017.04.038. Epub 2017 Jun 6. J Invest Dermatol. 2017. PMID: 28595998 Free article. Review.
CXXC5 was upregulated in miniaturized hair follicles and arrector pili muscles in human balding scalps. ...Moreover, CXXC5(-/-) mice displayed accelerated hair regrowth, and treatment with valproic acid, a glycogen synthase kinase 3beta inhibitor that activates the …
CXXC5 was upregulated in miniaturized hair follicles and arrector pili muscles in human balding scalps. ...Moreover, CXXC5(-/- …
Inhibition of CXXC5 function rescues Alzheimer's disease phenotypes by restoring Wnt/beta-catenin signaling pathway.
Yoon M, Kim H, Shin H, Lee H, Kang MJ, Park SH, Han G, Kim Y, Choi KY. Yoon M, et al. Pharmacol Res. 2023 Aug;194:106836. doi: 10.1016/j.phrs.2023.106836. Epub 2023 Jun 22. Pharmacol Res. 2023. PMID: 37355147 Free article.
The level of CXXC5 was upregulated, upon aging of 5xFAD mice. AD characteristics including cognitive deficits, amyloid-beta (Abeta) plaques, neuronal inflammation, and age-dependent increment of AD-related markers were rescued in Cxxc5(-/-)/5xFAD mice. 5-methoxyindi …
The level of CXXC5 was upregulated, upon aging of 5xFAD mice. AD characteristics including cognitive deficits, amyloid-beta (Abeta) p …
CXXC5 Mediates P. gingivalis-suppressed Cementoblast Functions Partially via MAPK Signaling Network.
Ma L, Wang X, Liu H, Jiang C, Liao H, Xu S, Guo Y, Cao Z. Ma L, et al. Int J Biol Sci. 2019 Jun 4;15(8):1685-1695. doi: 10.7150/ijbs.35419. eCollection 2019. Int J Biol Sci. 2019. PMID: 31360111 Free PMC article.
CXXC5 overexpression facilitated differentiation, and therefore attenuated the P. gingivalis-repressed effects on OCCM-30 cells. ...Overall, our experiment demonstrated a novel function of CXXC5 in the regeneration of impaired cementum caused by P. gingivalis invasi …
CXXC5 overexpression facilitated differentiation, and therefore attenuated the P. gingivalis-repressed effects on OCCM-30 cells. ...O …
Zinc-finger protein CXXC5 promotes breast carcinogenesis by regulating the TSC1/mTOR signaling pathway.
Wang W, Zhang Z, Zhao M, Wang Y, Ge Y, Shan L. Wang W, et al. J Biol Chem. 2023 Jan;299(1):102812. doi: 10.1016/j.jbc.2022.102812. Epub 2022 Dec 17. J Biol Chem. 2023. PMID: 36539038 Free PMC article.
CXXC5, a member of the CXXC family of zinc-finger proteins, is associated with numerous pathological processes. However, the pathophysiological function of CXXC5 has not been clearly established. Herein, we found that CXXC5 interacts with the CRL4B and NuRD c …
CXXC5, a member of the CXXC family of zinc-finger proteins, is associated with numerous pathological processes. However, the pathophy …
106 results