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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
1999 1
2000 3
2002 2
2004 2
2005 2
2006 1
2007 1
2008 2
2009 2
2010 3
2011 4
2012 7
2013 7
2014 4
2015 5
2016 5
2017 4
2018 8
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2020 6
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2022 10
2023 12
2024 3

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108 results

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Page 1
The association between CTSZ methylation in peripheral blood and breast cancer in Chinese women.
Li J, Zhou X, Li L, Ji L, Li J, Qu Y, Wang Z, Zhao Y, Zhang J, Liang F, Liu J, Gu W, Yang R, Ma F, Dai L. Li J, et al. Front Oncol. 2023 May 18;13:1148635. doi: 10.3389/fonc.2023.1148635. eCollection 2023. Front Oncol. 2023. PMID: 37274256 Free PMC article.
RESULTS: Our analysis showed that five out of the seven CpG sites exhibited significant associations with hypomethylation of CTSZ and BC, compared to healthy controls. The highest OR was for Q2 of CTSZ_CpG_1 (OR: 1.62, P=0.006), particularly for early-stage breast c …
RESULTS: Our analysis showed that five out of the seven CpG sites exhibited significant associations with hypomethylation of CTSZ and …
Single-cell and spatial analyses reveal the association between gene expression of glutamine synthetase with the immunosuppressive phenotype of APOE+CTSZ+TAM in cancers.
Wei J, Yu W, Chen J, Huang G, Zhang L, Chen Z, Hu M, Gong X, Du H. Wei J, et al. Mol Oncol. 2023 Apr;17(4):611-628. doi: 10.1002/1878-0261.13373. Epub 2023 Jan 21. Mol Oncol. 2023. PMID: 36587392 Free PMC article.
The proportion of APOE+CTSZ+TAM and regulatory T cells (Treg) were positively correlated across CRC scRNA-seq samples. APOE+CTSZ+TAM potentially interacted with Treg via CXCL16-CCR6 signals, as seen by ligand-receptor interactions analysis. ...
The proportion of APOE+CTSZ+TAM and regulatory T cells (Treg) were positively correlated across CRC scRNA-seq samples. APOE+CTSZ
NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population.
Nishida N, Aiba Y, Hitomi Y, Kawashima M, Kojima K, Kawai Y, Ueno K, Nakamura H, Yamashiki N, Tanaka T, Tamura S, Mori A, Yagi S, Soejima Y, Yoshizumi T, Takatsuki M, Tanaka A, Harada K, Shimoda S, Komori A, Eguchi S, Maehara Y, Uemoto S, Kokudo N, Nagasaki M, Tokunaga K, Nakamura M. Nishida N, et al. Sci Rep. 2018 May 23;8(1):8071. doi: 10.1038/s41598-018-26369-6. Sci Rep. 2018. PMID: 29795304 Free PMC article.
High-density association mapping at the CTSZ and negative elongation factor complex member C/D (NELFCD) loci, which are located within a strong linkage disequilibrium (LD) block, revealed that an intronic SNP of CTSZ, rs163800, was significantly associated with jaun …
High-density association mapping at the CTSZ and negative elongation factor complex member C/D (NELFCD) loci, which are located withi …
The FACT complex facilitates expression of lysosomal and antioxidant genes through binding to TFEB and TFE3.
Jeong E, Martina JA, Contreras PS, Lee J, Puertollano R. Jeong E, et al. Autophagy. 2022 Oct;18(10):2333-2349. doi: 10.1080/15548627.2022.2029671. Epub 2022 Mar 1. Autophagy. 2022. PMID: 35230915 Free PMC article.
Together, our data show that chromatin remodeling at the promoter of stress-responsive genes by FACT is important for efficient expression of TFEB and TFE3 targets, thus providing a link between environmental changes, chromatin modifications and transcriptional regulation.Abbrevi …
Together, our data show that chromatin remodeling at the promoter of stress-responsive genes by FACT is important for efficient expression o …
Association of CTSZ rs34069356 and MC3R rs6127698 gene polymorphisms with pulmonary tuberculosis.
Hashemi M, Eskandari-Nasab E, Moazeni-Roodi A, Naderi M, Sharifi-Mood B, Taheri M. Hashemi M, et al. Int J Tuberc Lung Dis. 2013 Sep;17(9):1224-8. doi: 10.5588/ijtld.12.0762. Epub 2013 Jul 3. Int J Tuberc Lung Dis. 2013. PMID: 23827504
OBJECTIVE: To evaluate the possible association between cathepsin Z (CTSZ) rs34069356 C/T (Ala286Thr) and melanocortin-3 receptor (MC3R) rs6127698 G>T (-484 G/T) gene polymorphisms and pulmonary tuberculosis (PTB) in an Iranian sample population. ...CONCLUSION: Our data …
OBJECTIVE: To evaluate the possible association between cathepsin Z (CTSZ) rs34069356 C/T (Ala286Thr) and melanocortin-3 receptor (MC …
Novel Drug Targets for Atrial Fibrillation Identified Through Mendelian Randomization Analysis of the Blood Proteome.
Ning Z, Huang Y, Lu H, Zhou Y, Tu T, Ouyang F, Liu Y, Liu Q. Ning Z, et al. Cardiovasc Drugs Ther. 2023 May 22. doi: 10.1007/s10557-023-07467-8. Online ahead of print. Cardiovasc Drugs Ther. 2023. PMID: 37212950
Genetically predicted 12 proteins increased AF risk (TES, CFL2, MTHFD1, RAB1A, DUSP13, SRL, ANXA4, NEO1, FKBP7, SPON1, LPA, MANBA); 18 proteins decreased AF risk (PMVK, UBE2F, SYT11, CHMP3, PFKM, FBP1, TNFSF12, CTSZ, QSOX2, ALAD, EFEMP1, FLRT2, LRIG1, OLA1, SH3BGRL3, IL6R, …
Genetically predicted 12 proteins increased AF risk (TES, CFL2, MTHFD1, RAB1A, DUSP13, SRL, ANXA4, NEO1, FKBP7, SPON1, LPA, MANBA); 18 prote …
Characterization, expression profiling and functional characterization of cathepsin Z (CTSZ) in turbot (Scophthalmus maximus L.).
Cai X, Gao C, Song H, Yang N, Fu Q, Tan F, Li C. Cai X, et al. Fish Shellfish Immunol. 2019 Jan;84:599-608. doi: 10.1016/j.fsi.2018.10.046. Epub 2018 Oct 22. Fish Shellfish Immunol. 2019. PMID: 30359754
Cathepsin Z (CTSZ) is a lysosomal cysteine protease of the papain superfamily. ...The syntenic analysis revealed the similar neighboring genes of CTSZ across all the selected species, which suggested the synteny encompassing CTSZ region during vertebrate evol …
Cathepsin Z (CTSZ) is a lysosomal cysteine protease of the papain superfamily. ...The syntenic analysis revealed the similar neighbor …
Deguelin attenuates non-small cell lung cancer cell metastasis through inhibiting the CtsZ/FAK signaling pathway.
Li W, Yu X, Ma X, Xie L, Xia Z, Liu L, Yu X, Wang J, Zhou H, Zhou X, Yang Y, Liu H. Li W, et al. Cell Signal. 2018 Oct;50:131-141. doi: 10.1016/j.cellsig.2018.07.001. Epub 2018 Jul 7. Cell Signal. 2018. PMID: 30018008
These inhibitory effects of deguelin were mediated by suppressing of Cathepsin Z (CtsZ) expression and interrupting the interaction of CtsZ with integrin beta3. Moreover, deguelin inhibits the activation of CtsZ downstream FAK/Src/Paxillin signaling. Knockdow …
These inhibitory effects of deguelin were mediated by suppressing of Cathepsin Z (CtsZ) expression and interrupting the interaction o …
Polymorphisms in MC3R promoter and CTSZ 3'UTR are associated with tuberculosis susceptibility.
Adams LA, Möller M, Nebel A, Schreiber S, van der Merwe L, van Helden PD, Hoal EG. Adams LA, et al. Eur J Hum Genet. 2011 Jun;19(6):676-81. doi: 10.1038/ejhg.2011.1. Epub 2011 Feb 2. Eur J Hum Genet. 2011. PMID: 21368909 Free PMC article.
CTSZ has been detected in immune cells, such as macrophages and monocytes, and it is hypothesized that the protein may play a role in the immune response. ...Six SNPs in MC3R and eight in CTSZ were genotyped and haplotypes were inferred. SNP rs6127698 in the promote
CTSZ has been detected in immune cells, such as macrophages and monocytes, and it is hypothesized that the protein may play a role in
Macrophage-Specific Cathepsin as a Marker Correlated with Prognosis and Tumor Microenvironmental Characteristics of Clear Cell Renal Cell Carcinoma.
Zhang F, Liang J, Lu Y, Tang Y, Liu S, Wu K, Zhang F, Lu Y, Liu Z, Wang X. Zhang F, et al. J Inflamm Res. 2022 Nov 11;15:6275-6292. doi: 10.2147/JIR.S375250. eCollection 2022. J Inflamm Res. 2022. PMID: 36386587 Free PMC article.
Immunohistochemistry indicated that CTSZ was expressed in tumors infiltrated with lymphocytes. Double immunofluorescence demonstrated that CTSZ was co-expressed with CD68 but not CD8. ...Hypomethylation modification of cg02744249, cg02744249, and cg22145559 were neg …
Immunohistochemistry indicated that CTSZ was expressed in tumors infiltrated with lymphocytes. Double immunofluorescence demonstrated …
108 results